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List of works by Mark Hedglin

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

scientific article published on 22 October 2016

Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors

scientific article published on 25 February 2007

Eukaryotic Translesion DNA Synthesis on the Leading and Lagging Strands: Unique Detours around the Same Obstacle

scientific article

Hopping enables a DNA repair glycosylase to search both strands and bypass a bound protein.

scientific article

Isolating contributions from intersegmental transfer to DNA searching by alkyladenine DNA glycosylase.

scientific article published on 09 July 2013

Monitoring the Retention of Human Proliferating Cell Nuclear Antigen at Primer/Template Junctions by Proteins That Bind Single-Stranded DNA.

scientific article

PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments

scientific article published on 27 November 2020

PCNA monoubiquitination is regulated by diffusion of Rad6/Rad18 complexes along RPA filaments

scientific article published on 12 August 2020

Probing the DNA structural requirements for facilitated diffusion.

scientific article

Rad6/Rad18 Competes with DNA Polymerases η and δ for PCNA Encircling DNA

scientific article published on 10 January 2020

Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance.

scientific article published on June 2015

Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA.

scientific article

Replication clamps and clamp loaders.

scientific article published on April 2013

Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen

scientific article published on 30 January 2019

Stability of the human polymerase δ holoenzyme and its implications in lagging strand DNA synthesis.

scientific article published on 14 March 2016

Stepwise assembly of the human replicative polymerase holoenzyme.

scientific article published on 2 April 2013

Structure of the human clamp loader reveals an autoinhibited conformation of a substrate-bound AAA+ switch

scientific article published on 09 September 2020