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List of works by Saleela M Ruwanpura

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

scientific article published on 01 April 2019

Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma.

scientific article

Deoxyribonuclease 1 reduces pathogenic effects of cigarette smoke exposure in the lung

scientific article published on 21 September 2017

Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice

scientific article published on 20 January 2012

Developmentally distinct in vivo effects of FSH on proliferation and apoptosis during testis maturation

scientific journal article

Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis.

scientific article published on 14 April 2014

Follicle-stimulating hormone affects spermatogonial survival by regulating the intrinsic apoptotic pathway in adult rats.

scientific article

Gonadotrophins regulate germ cell survival, not proliferation, in normal adult men.

scientific article

Hormonal regulation of male germ cell development.

scientific article published on 09 February 2010

IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice.

scientific article published on 10 February 2014

IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis.

scientific article published on 7 January 2016

Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL-18 mediated inflammation-independent mechanism.

scientific article

Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.

scientific article published on 4 February 2011

Lung Diseases

scientific article published on 01 January 2018

Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice

scientific article

Pathways involved in testicular germ cell apoptosis in immature rats after FSH suppression.

scientific article

Pirfenidone: Molecular Mechanisms and Potential Clinical Applications in Lung Disease

scientific article published on 01 April 2020

The effect of testosterone, dihydrotestosterone and oestradiol on the re-initiation of spermatogenesis in the adult photoinhibited Djungarian hamster

scientific article

Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.

scientific article published on 2 July 2016

Tissue Processing for Stereological Analyses of Lung Structure in Chronic Obstructive Pulmonary Disease.

scientific article published in January 2018

Transcriptional regulation of inflammasome-associated pattern recognition receptors, and the relevance to disease pathogenesis.

scientific article

Tumor Cell Response to Synchrotron Microbeam Radiation Therapy Differs Markedly From Cells in Normal Tissues

article