List of works - Ryan E Looper

( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible ⬇️

scientific article published on 07 February 2013

A Cancer-Selective Zinc Ionophore Inspired by the Natural Product Naamidine A

scientific article published on 08 January 2019

A Direct C11 Alkylation Strategy on the Saxitoxin Core: A Synthesis of (+)-11-Saxitoxinethanoic Acid

scientific article published on 25 September 2019

A stereocontrolled synthesis of (+)-saxitoxin.

scientific article published on 23 November 2011

Access to the pactamycin core via an epoxide opening cascade

scientific article published on 03 July 2012

Addition-hydroamination reactions of propargyl cyanamides: rapid access to highly substituted 2-aminoimidazoles.

scientific article

Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor

scientific article

Chemical genetic screen reveals a role for desmosomal adhesion in mammary branching morphogenesis.

scientific article published on 3 December 2012

Chlorotrimethylsilane Activation of Acylcyanamides for the Synthesis of Mono-N-acylguanidines ⬇️

scientific article published on July 19, 2011

Development of a screen to identify selective small molecules active against patient-derived metastatic and chemoresistant breast cancer cells

scientific article

Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity.

scholarly article

Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate.

scientific article

Macrocycloadditions leading to conformationally restricted small molecules

scientific article published on 01 May 2006

Preparation of Mono-Cbz Protected Guanidines.

scientific article published on January 2015

Preparation of a 1,2-isoxazolidine synthon for the synthesis of zetekitoxin AB.

scientific article published on November 2015

Regioselective Base-Mediated Cyclizations of Mono-N-acylpropargylguanidines

scientific article published on 30 May 2017

Regioselective rhodium(II)-catalyzed hydroaminations of propargylguanidines.

scientific article

Small Molecular Weapons against Multi-Drug Resistance

scientific article published in 2021

Synthesis of 2-thio- and 2-oxoimidazoles via cascade addition-cycloisomerization reactions of propargylcyanamides.

scientific article published in January 2010

Synthesis of Naamidine A and Selective Access to N(2)-Acyl-2-aminoimidazole Analogues

scientific article published on 11 September 2015

Synthesis of aromatic bisabolene natural products via palladium-catalyzed cross-couplings of organozinc reagents.

scientific article published in April 2004

Synthesis of bicyclic guanidines via cascade hydroamination/Michael additions of mono-N-acryloylpropargylguanidines.

scientific article published on 13 November 2014

Synthesis of cytimidine through a one-pot copper-mediated amidation cascade

scientific article published in 2011

Synthesis of the Reported Structures for Kealiinines B and C ⬇️

scientific article published on September 11, 2012

Synthesis of the putative structure of 7-deoxycylindrospermopsin: C7 oxygenation is not required for the inhibition of protein synthesis.

scientific article published in June 2005

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

scientific article

Unifying the aminohexopyranose- and peptidyl-nucleoside antibiotcs; implications for antibiotic design

scientific article published on 27 April 2020

List of works by Ryan E Looper

( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible ⬇️

A Cancer-Selective Zinc Ionophore Inspired by the Natural Product Naamidine A

A Direct C11 Alkylation Strategy on the Saxitoxin Core: A Synthesis of (+)-11-Saxitoxinethanoic Acid

A stereocontrolled synthesis of (+)-saxitoxin.

Access to the pactamycin core via an epoxide opening cascade

Addition-hydroamination reactions of propargyl cyanamides: rapid access to highly substituted 2-aminoimidazoles.

Bis-aryloxadiazoles as effective activators of the aryl hydrocarbon receptor

Chemical genetic screen reveals a role for desmosomal adhesion in mammary branching morphogenesis.

Chlorotrimethylsilane Activation of Acylcyanamides for the Synthesis of Mono-N-acylguanidines ⬇️

Development of a screen to identify selective small molecules active against patient-derived metastatic and chemoresistant breast cancer cells

Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity.

Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate.

Macrocycloadditions leading to conformationally restricted small molecules

Preparation of Mono-Cbz Protected Guanidines.

Preparation of a 1,2-isoxazolidine synthon for the synthesis of zetekitoxin AB.

Regioselective Base-Mediated Cyclizations of Mono-N-acylpropargylguanidines

Regioselective rhodium(II)-catalyzed hydroaminations of propargylguanidines.

Small Molecular Weapons against Multi-Drug Resistance

Synthesis of 2-thio- and 2-oxoimidazoles via cascade addition-cycloisomerization reactions of propargylcyanamides.

Synthesis of Naamidine A and Selective Access to N(2)-Acyl-2-aminoimidazole Analogues

Synthesis of aromatic bisabolene natural products via palladium-catalyzed cross-couplings of organozinc reagents.

Synthesis of bicyclic guanidines via cascade hydroamination/Michael additions of mono-N-acryloylpropargylguanidines.

Synthesis of cytimidine through a one-pot copper-mediated amidation cascade

Synthesis of the Reported Structures for Kealiinines B and C ⬇️

Synthesis of the putative structure of 7-deoxycylindrospermopsin: C7 oxygenation is not required for the inhibition of protein synthesis.

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

Unifying the aminohexopyranose- and peptidyl-nucleoside antibiotcs; implications for antibiotic design