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List of works by Xue Gao

A general theoretical framework to design base editors with reduced bystander effects

scientific article published on 11 November 2021

Assembly of asperlicin peptidyl alkaloids from anthranilate and tryptophan: a two-enzyme pathway generates heptacyclic scaffold complexity in asperlicin E

scientific article published on 9 October 2012

Complexity generation during natural product biosynthesis using redox enzymes ⬇️

scientific article published on May 6, 2012

Complexity generation in fungal peptidyl alkaloid biosynthesis: a two-enzyme pathway to the hexacyclic MDR export pump inhibitor ardeemin

scientific article

Complexity generation in fungal peptidyl alkaloid biosynthesis: oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from Aspergillus fumigatus. ⬇️

scientific article

Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain

scientific article

Directed Evolution and Structural Characterization of a Simvastatin Synthase

scientific article

Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.

scientific article published on 29 February 2016

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.

scientific article published on 28 February 2018

Fungal Indole Alkaloid Biosynthesis: Genetic and Biochemical Investigation of the Tryptoquialanine Pathway in Penicillium aethiopicum ⬇️

scientific article published on February 7, 2011

Genetic characterization of enzymes involved in the priming steps of oxytetracycline biosynthesis in Streptomyces rimosus

scientific article published on 26 May 2011

Heterologous expression and manipulation of three tetracycline biosynthetic pathways.

scientific article published on 28 September 2012

Integrative investigation of lipidome and signal pathways in human endothelial cells under oxidative stress ⬇️

scientific article published on May 23, 2011

Multiplex base- and prime-editing with drive-and-process CRISPR arrays

scientific article published on 19 May 2022

Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity.

scientific article

Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects

scientific article published on 15 July 2020

Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins ⬇️

scientific article published on 06 July 2021

Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.

scientific article published on 20 December 2017

Unraveling terminal C-domain-mediated condensation in fungal biosynthesis of imidazoindolone metabolites.

scientific article

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