Search filters

List of works by Ewa Malc

A Case Study of Genomic Instability in an Industrial Strain of

scientific article published on 06 November 2018

APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication

scientific article

APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast.

scientific article published on 21 March 2017

Break-induced replication is a source of mutation clusters underlying kataegis

scientific article

Cavitation Enhancing Nanodroplets Mediate Efficient DNA Fragmentation in a Bench Top Ultrasonic Water Bath.

scientific article

Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.

scientific article

Congenital Midline Cervical Cleft: First Report and Genetic Analysis of Two Related Patients

scientific article published on 06 February 2020

Gene copy-number variation in haploid and diploid strains of the yeast Saccharomyces cerevisiae

scientific article published on 10 January 2013

Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity.

scientific article published on 14 September 2017

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.

scientific article

High-resolution genome-wide analysis of irradiated (UV and γ-rays) diploid yeast cells reveals a high frequency of genomic loss of heterozygosity (LOH) events

scientific article published on 20 January 2012

Inactivation of the 20S proteasome maturase, Ump1p, leads to the instability of mtDNA in Saccharomyces cerevisiae

scientific article published on 23 May 2009

Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages

scientific article published on 09 March 2020

Msh1p counteracts oxidative lesion-induced instability of mtDNA and stimulates mitochondrial recombination in Saccharomyces cerevisiae

scientific article

Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements

scientific article published on 01 October 2019

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

scientific article published on 30 September 2019

Repair of oxidative damage in mitochondrial DNA of Saccharomyces cerevisiae: involvement of the MSH1-dependent pathway.

scientific article published on April 2004

The generation of oxidative stress-induced rearrangements in Saccharomyces cerevisiae mtDNA is dependent on the Nuc1 (EndoG/ExoG) nuclease and is enhanced by inactivation of the MRX complex

scientific article published on 28 December 2012

The impact of environmental and endogenous damage on somatic mutation load in human skin fibroblasts

journal article published in 2016

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.

scientific article

Variant calling in low-coverage whole genome sequencing of a Native American population sample

scientific article published on 30 January 2014