List of works - Alexei S Soares

Quantitative assessment of peptide sequence diversity in M13 combinatorial peptide phage display libraries

scientific article

Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2: BINDING STUDIES AND CRYSTAL STRUCTURE

scientific article

Acoustic methods for high-throughput protein crystal mounting at next-generation macromolecular crystallographic beamlines

scientific article

Structural basis for NADH/NAD+ redox sensing by a Rex family repressor

scientific article

Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.

scientific article

Crystal Structure of a Complex between the Phosphorelay Protein YPD1 and the Response Regulator Domain of SLN1 Bound to a Phosphoryl Analog

scientific article

Acoustically mounted microcrystals yield high-resolution X-ray structures.

scientific article

Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin

scientific article

Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin

scientific article published on 05 May 2006

Determinants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with Mesotrypsin

scientific article

Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes

scientific article

The P 2 ′ residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity

scientific article

Estimating the diversity of peptide populations from limited sequence data

scientific article

Integrated software for macromolecular crystallography synchrotron beamlines II: revision, robots and a database

scientific article published on 18 October 2006

Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes

scientific article

Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation

scientific article

Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates

scientific article

Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin

scientific article

Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors

scientific article

High throughput screening using acoustic droplet ejection to combine protein crystals and chemical libraries on crystallization plates at high density

scientific article

Mail-in crystallography program at Brookhaven National Laboratory's National Synchrotron Light Source

scientific article published on 18 October 2006

Structural insights of non-canonical U*U pair and Hoogsteen interaction probed with Se atom

scientific article

Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site

scientific article

Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone

scientific article

Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening

scientific article

A linear relationship between crystal size and fragment binding time observed crystallographically: implications for fragment library screening using acoustic droplet ejection

scientific article

Three-beam interference is a sensitive measure of the efficacy of macromolecular refinement techniques

scientific article published on September 19, 2003

Solvent minimization induces preferential orientation and crystal clustering in serial micro-crystallography on micro-meshes, in situ plates and on a movable crystal conveyor belt

scientific article

An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis

scientific article

A simple technique to reduce evaporation of crystallization droplets by using plate lids with apertures for adding liquids

scientific article

Macromolecular crystallography beamline X25 at the NSLS.

scientific article

The structures of penicillin binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into β-lactam resistance

scientific article published in Journal of Biological Chemistry

High-speed raster-scanning synchrotron serial microcrystallography with a high-precision piezo-scanner

scientific article published on 23 August 2018

Acoustic Methods to Monitor Protein Crystallization and to Detect Protein Crystals in Suspensions of Agarose and Lipidic Cubic Phase

scientific article

Optics Concept for a Pair of Undulator Beamlines for MX.

scientific article

Synthesis, structure and imaging of oligodeoxyribonucleotides with tellurium-nucleobase derivatization

scientific article

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

scientific article

Expression, purification and preliminary diffraction studies of PhnP

scientific article published on 24 May 2008

Crystallographic characterization of the nitric oxide derivative of R-state human hemoglobin

scientific article

Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II

scientific article published on 30 January 2019

Small molecule inhibitors of mesotrypsin from a structure-based docking screen

scientific article

Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking

scientific article published on 24 November 2020

Best practices for high data-rate macromolecular crystallography (HDRMX)

scientific article published on 09 January 2020

Using sound pulses to solve the crystal-harvesting bottleneck

scientific article

Expression, purification and preliminary diffraction studies of CmlS

scientific article published on 26 February 2009

Structure of the catalytic chain ofMethanococcus jannaschiiaspartate transcarbamoylase in a hexagonal crystal form: insights into the path of carbamoyl phosphate to the active site of the enzyme

scientific article

Maintaining Microclimates during Nanoliter Chemical Dispensations Using Custom-Designed Source Plate Lids

scientific article published on 12 November 2015

A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs

scientific article published on 14 December 2020

The use of haptic interfaces and web services in crystallography: an application for a 'screen to beam' interface.

scientific article published on 11 November 2016

Serial Crystallography with Multi-stage Merging of 1000's of Images

scholarly article published 24 May 2017

List of works by Alexei S Soares

Quantitative assessment of peptide sequence diversity in M13 combinatorial peptide phage display libraries

Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2: BINDING STUDIES AND CRYSTAL STRUCTURE

Acoustic methods for high-throughput protein crystal mounting at next-generation macromolecular crystallographic beamlines

Structural basis for NADH/NAD+ redox sensing by a Rex family repressor

Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.

Crystal Structure of a Complex between the Phosphorelay Protein YPD1 and the Response Regulator Domain of SLN1 Bound to a Phosphoryl Analog

Acoustically mounted microcrystals yield high-resolution X-ray structures.

Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin

Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin

Determinants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with Mesotrypsin

Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes

The P 2 ′ residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity

Estimating the diversity of peptide populations from limited sequence data

Integrated software for macromolecular crystallography synchrotron beamlines II: revision, robots and a database

Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes

Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation

Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates

Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin

Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors

High throughput screening using acoustic droplet ejection to combine protein crystals and chemical libraries on crystallization plates at high density

Mail-in crystallography program at Brookhaven National Laboratory's National Synchrotron Light Source

Structural insights of non-canonical U*U pair and Hoogsteen interaction probed with Se atom

Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site

Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone

Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening

A linear relationship between crystal size and fragment binding time observed crystallographically: implications for fragment library screening using acoustic droplet ejection

Three-beam interference is a sensitive measure of the efficacy of macromolecular refinement techniques

Solvent minimization induces preferential orientation and crystal clustering in serial micro-crystallography on micro-meshes, in situ plates and on a movable crystal conveyor belt

An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis

A simple technique to reduce evaporation of crystallization droplets by using plate lids with apertures for adding liquids

Macromolecular crystallography beamline X25 at the NSLS.

The structures of penicillin binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into β-lactam resistance

High-speed raster-scanning synchrotron serial microcrystallography with a high-precision piezo-scanner

Acoustic Methods to Monitor Protein Crystallization and to Detect Protein Crystals in Suspensions of Agarose and Lipidic Cubic Phase

Optics Concept for a Pair of Undulator Beamlines for MX.

Synthesis, structure and imaging of oligodeoxyribonucleotides with tellurium-nucleobase derivatization

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

Expression, purification and preliminary diffraction studies of PhnP

Crystallographic characterization of the nitric oxide derivative of R-state human hemoglobin

Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II

Small molecule inhibitors of mesotrypsin from a structure-based docking screen

Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking

Best practices for high data-rate macromolecular crystallography (HDRMX)

Using sound pulses to solve the crystal-harvesting bottleneck

Expression, purification and preliminary diffraction studies of CmlS

Structure of the catalytic chain ofMethanococcus jannaschiiaspartate transcarbamoylase in a hexagonal crystal form: insights into the path of carbamoyl phosphate to the active site of the enzyme

Maintaining Microclimates during Nanoliter Chemical Dispensations Using Custom-Designed Source Plate Lids

A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs

The use of haptic interfaces and web services in crystallography: an application for a 'screen to beam' interface.

Serial Crystallography with Multi-stage Merging of 1000's of Images