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List of works by Sean G Brown

A Ba2+-resistant, acid-sensitive K+ conductance in Na+-absorbing H441 human airway epithelial cells.

scientific article published on 2 February 2007

A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels

scientific article published on 18 December 2015

Cation currents in human airway epithelial cells induced by infection with influenza A virus.

scientific article published on 29 April 2009

Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity.

scientific article published on 14 August 2014

Complex CatSper-dependent and independent [Ca2+]i signalling in human spermatozoa induced by follicular fluid

scientific article published in October 2017

Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF.

scientific article published on 6 April 2016

Differential phosphoinositide binding to components of the G protein-gated K+ channel

scientific article published on 01 May 2006

Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem.

scientific article

Homozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacity

scientific article published on 01 October 2018

Novel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function

scientific article published on 11 December 2019

PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells.

scientific article

Single-cell analysis of [Ca2+]i signalling in sub-fertile men: characteristics and relation to fertilization outcome

scientific article published on 25 April 2018

Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa.

scientific article

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