List of works by Frederikus A Klok

A simple non-invasive diagnostic algorithm for ruling out chronic thromboembolic pulmonary hypertension in patients after acute pulmonary embolism.

scientific article published on 30 March 2011

Abnormal vaginal bleeding in women of reproductive age treated with edoxaban or warfarin for venous thromboembolism: a post hoc analysis of the Hokusai-VTE study

scientific article published on 20 July 2018

Accuracy and reproducibility of CT right-to-left ventricular diameter measurement in patients with acute pulmonary embolism.

scientific article

Accurate diagnosis of iliac vein thrombosis in pregnancy with magnetic resonance direct thrombus imaging (MRDTI)

scientific article published on 13 December 2016

Advances in the diagnosis and management of acute pulmonary embolism

scientific article published on May 2014

Alternative diagnosis other than pulmonary embolism as a subjective variable in the Wells clinical decision rule: not so bad after all

scientific article published on 01 May 2007

Anticoagulation in splanchnic and cerebral vein thrombosis: Still groping in the dark

scientific article published on 14 September 2020

Antithrombotic therapy after mitral valve repair: VKA or aspirin?

scientific article published on 01 November 2018

Association between micro particle-tissue factor activity, factor VIII activity and recurrent VTE in patients with acute pulmonary embolism

scientific article

Brain-type natriuretic peptide levels in the prediction of adverse outcome in patients with pulmonary embolism: a systematic review and meta-analysis.

scientific article published on 12 June 2008

COVID‐19 associated coagulopathy and thromboembolic disease: Commentary on an interim expert guidance

scientific article published on 21 April 2020

Chronic pulmonary embolism and pulmonary hypertension.

scientific article published on April 2012

Chronic thromboembolic pulmonary hypertension from the perspective of patients with pulmonary embolism

scientific article published on 08 May 2018

Clinical effects of antiplatelet drugs and statins on D-dimer levels

scientific article published on 13 May 2018

Cohort Study on the Management of Cancer-Associated Venous Thromboembolism Aimed at the Safety of Stopping Anticoagulant Therapy in Patients Cured of Cancer

scientific article published on 13 January 2016

Combination of Pulmonary Embolism Rule-out Criteria and YEARS Algorithm in a European Cohort of Patients with Suspected Pulmonary Embolism.

scientific article published in February 2018

Comparison of CT assessed right ventricular size and cardiac biomarkers for predicting short-term clinical outcome in normotensive patients suspected of having acute pulmonary embolism.

scientific article published on 24 January 2010

Comparison of risk profile and clinical outcome of patients after acute pulmonary embolism in university and non-university hospitals.

scientific article published on 13 November 2009

Comparison of the clinical usefulness of two quantitative D-Dimer tests in patients with a low clinical probability of pulmonary embolism

scientific article published on 24 September 2008

Comparison of the revised Geneva score with the Wells rule for assessing clinical probability of pulmonary embolism

scientific article published on 29 October 2007

Computed tomography pulmonary angiography ventilation-perfusion lung scanning for diagnosing pulmonary embolism during pregnancy: a systematic review and meta-analysis

scientific article published on 16 August 2018

Continuation of low-molecular-weight heparin treatment for cancer-related venous thromboembolism: a prospective cohort study in daily clinical practice.

scientific article published on 5 November 2016

Controversies in venous thromboembolism--2015.

scientific article published on 17 July 2015

Coronary or thoracic artery calcium score in provoked and unprovoked pulmonary embolism: a case-control study.

scientific article published on 10 February 2016

Correction to: Antithrombotic therapy after mitral valve repair: VKA or aspirin?

scientific article published on 01 November 2018

Current and future perspectives in imaging of venous thromboembolism

scientific article published on 11 July 2016

Current challenges in diagnostic imaging of venous thromboembolism

scientific article

Current challenges in diagnostic imaging of venous thromboembolism

scientific article published on 01 January 2015

Current standings in diagnostic management of acute venous thromboembolism: Still rough around the edges

scientific article published on 16 July 2015

D-dimer Interval Likelihood Ratios for Pulmonary Embolism.

scientific article

D-dimer testing in patients with suspected pulmonary embolism and impaired renal function.

scientific article published on 19 August 2009

Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study.

scientific article published on 6 December 2017

Derivation of a clinical prediction score for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism

scientific article published on 28 October 2015

Determinants of diagnostic delay in Chronic Thromboembolic Pulmonary Hypertension: results from the European CTEPH registry

scientific article published on 06 December 2018

Determining the minimal clinically important difference for the PEmbQoL questionnaire, a measure of pulmonary embolism-specific quality of life

scientific article published on 02 November 2018

Development and implementation of common data elements for venous thromboembolism research: on behalf of SSC Subcommittee on official Communication from the SSC of the ISTH

scientific article published on 01 January 2021

Diagnosing upper extremity deep vein thrombosis with non-contrast-enhanced Magnetic Resonance Direct Thrombus Imaging: A pilot study

scientific article published on 10 January 2018

Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism

scientific article published on 17 March 2020

Diagnosis of pulmonary embolism: Advances and pitfalls.

scientific article published on 31 July 2012

Diagnosis of recurrent venous thromboembolism.

scientific article published on 26 May 2017

Diagnostic accuracy of magnetic resonance imaging in patients with suspected pulmonary embolism: A bivariate meta-analysis.

scientific article

Diagnostic management of clinically suspected acute pulmonary embolism.

scientific article published on July 2009

Diagnostic outcome management study in patients with clinically suspected recurrent acute pulmonary embolism with a structured algorithm.

scientific article published on 2 April 2014

Differential impact of syncope on the prognosis of patients with acute pulmonary embolism: a systematic review and meta-analysis

scientific article published on 01 December 2018

Diplopia as the presenting symptom of type 1 diabetes

scientific article published on 01 January 2014

Direct Oral Anticoagulants for the Treatment of Acute Venous Thromboembolism Associated with Cancer: A Systematic Review and Meta-Analysis

scientific article published on 04 May 2020

Direct oral anticoagulant use and subsequent start of proton pump inhibitors as proxy for gastric complaints

scientific article published on 15 November 2018

Disease prevalence dependent failure rate in diagnostic management studies on suspected deep vein thrombosis: communication from the SSC of the ISTH.

scientific article published on 20 August 2017

ERS Statement on Chronic Thromboembolic Pulmonary Hypertension

scientific article published on 17 December 2020

Effectiveness and Safety of Apixaban for Treatment of Venous Thromboembolism in Daily Practice

scientific article published on 01 April 2020

Effectiveness and safety of novel oral anticoagulants as compared with vitamin K antagonists in the treatment of acute symptomatic venous thromboembolism: a systematic review and meta-analysis

scientific article

Efficacy and Safety of Outpatient Treatment Based on the Hestia Clinical Decision Rule with or without N-Terminal Pro-Brain Natriuretic Peptide Testing in Patients with Acute Pulmonary Embolism. A Randomized Clinical Trial

scientific article published on 01 October 2016

Efficacy and safety of vitamin K-antagonists (VKA) for atrial fibrillation in non-dialysis dependent chronic kidney disease.

scientific article

Efficacy and safety outcomes of recanalisation procedures in patients with acute symptomatic pulmonary embolism: systematic review and network meta-analysis.

scientific article published on 13 November 2017

Elevated D-dimer levels predict recurrence in patients with idiopathic venous thromboembolism: a meta-analysis.

scientific article published on 19 January 2009

Embolic burden of incidental pulmonary embolism diagnosed on routinely performed contrast-enhanced computed tomography imaging in cancer patients.

scientific article published in August 2013

Epidemiology and management of chronic thromboembolic pulmonary hypertension.

scientific article published on September 2010

Essential aspects of the follow-up after acute pulmonary embolism: An illustrated review

scientific article published on 02 August 2020

Establishing diagnostic criteria and treatment of subsegmental pulmonary embolism: A Delphi analysis of experts

scientific article published on 01 October 2020

Evaluation of VTE-BLEED for predicting intracranial or fatal bleeding in stable anticoagulated patients with venous thromboembolism

scientific article published on 19 April 2018

Evaluation of the new simple and objective clinical decision rule "I-DVT" in patients with clinically suspected acute deep vein thrombosis

scientific article published on 15 March 2016

Evaluation of the predictive value of the bleeding prediction score VTE-BLEED for recurrent venous thromboembolism

scientific article published on 25 May 2019

Excluding pulmonary embolism without imaging tests--can our diagnostic algorithm be optimized?

scientific article published in December 2008

External validation of a simple non-invasive algorithm to rule out chronic thromboembolic pulmonary hypertension after acute pulmonary embolism.

scientific article published on 13 December 2014

External validation of the VTE-BLEED score for predicting major bleeding in stable anticoagulated patients with venous thromboembolism

scientific article published on 09 March 2017

Factor V Leiden is associated with more distal location of deep vein thrombosis of the leg

scientific article published on 25 December 2007

Fatal recurrent VTE after anticoagulant treatment for unprovoked VTE: a systematic review

scientific article published on 28 November 2018

Follow-up after acute Pulmonary Embolism

scientific article published on 26 February 2018

From thrombosis to fibrosis in chronic thromboembolic pulmonary hypertension.

scientific article published on 2 February 2017

Healthcare utilization in chronic thromboembolic pulmonary hypertension after acute pulmonary embolism

scientific article published on 30 August 2018

High D-dimer level is associated with increased 15-d and 3 months mortality through a more central localization of pulmonary emboli and serious comorbidity

scientific article published on 19 November 2007

Home treatment of acute pulmonary embolism: state of the art in 2018

scientific article published on 01 September 2018

How I assess and manage the risk of bleeding in patients treated for venous thromboembolism

scientific article published on 01 March 2020

Imaging Tests for Suspected Deep Vein Thrombosis

scientific article published on 01 November 2015

Imaging tests in the diagnosis of pulmonary embolism.

scientific article published on April 2012

Impact of delay in clinical presentation on the diagnostic management and prognosis of patients with suspected pulmonary embolism

scientific article published on 01 June 2013

Improved identification of thrombolysis candidates amongst intermediate-risk pulmonary embolism patients: implications for future trials.

scientific article published on 18 January 2018

Incidence and impact of anticoagulation-associated abnormal menstrual bleeding in women after venous thromboembolism

scientific article published in 2022

Incidence and predictors of contrast-induced nephropathy following CT-angiography for clinically suspected acute pulmonary embolism

scientific article published on 23 November 2009

Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature.

scientific article published on 23 February 2017

Is a normal computed tomography pulmonary angiography safe to rule out acute pulmonary embolism in patients with a likely clinical probability?

scientific article published on 01 June 2017

Is pulmonary embolism associated with reactive mediastinal and hilar lymphadenopathy?

scientific article published on 28 April 2010

Is stand-alone D-dimer testing safe to rule out acute pulmonary embolism?

scientific article

Late outcomes of pulmonary embolism: The post-PE syndrome

scientific article published on 16 June 2017

Less abnormal uterine bleeding with dabigatran than warfarin in women treated for acute venous thromboembolism

scientific article published on 11 August 2018

Letter by Barco et al Regarding Article, "Restarting Anticoagulant Therapy After Intracranial Hemorrhage: A Systematic Review and Meta-Analysis"

scientific article published on 07 August 2017

Letter by Klok et al Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus".

scientific article

Lower prevalence of subsegmental pulmonary embolism after application of the YEARS diagnostic algorithm.

scientific article published on 10 September 2018

Magnetic resonance direct thrombus imaging differentiates acute recurrent ipsilateral deep vein thrombosis from residual thrombosis

scientific article published on 13 June 2014

Magnetic resonance imaging for diagnosis of acute pulmonary embolism: not yet a suitable alternative to CT-PA.

scientific article

Management and treatment of deep vein thrombosis in special populations

scientific article published on 25 July 2018

Management of incidental pulmonary embolism

scientific article

Management of intermediate-risk pulmonary embolism: uncertainties and challenges.

scientific article published on 25 June 2015

Measurement of right and left ventricular function by ECG-synchronized CT scanning in patients with acute pulmonary embolism: usefulness for predicting short-term outcome

article

Measuring functional limitations after venous thromboembolism: A call to action

scientific article published on 07 April 2019

Meta-analysis of the efficacy and safety of new oral anticoagulants in patients with cancer-associated acute venous thromboembolism

scientific article

Meta-analysis of the efficacy and safety of new oral anticoagulants in patients with cancer-associated acute venous thromboembolism: reply

scientific article published on 11 November 2014

No added value of the age-adjusted D-dimer cut-off to the YEARS algorithm in patients with suspected pulmonary embolism

scientific article

Novel Anticoagulant Treatment for Pulmonary Embolism with Direct Oral Anticoagulants Phase 3 Trials and Clinical Practice

scientific article published on 04 June 2018

One versus two years of elastic compression stockings for prevention of post-thrombotic syndrome (OCTAVIA study): randomised controlled trial

scientific article

Optimization of the diagnostic management of clinically suspected pulmonary embolism in hospitalized patients.

scientific article published on 22 August 2014

Oral contraception and menstrual bleeding during treatment of venous thromboembolism: Expert opinion versus current practice: Combined results of a systematic review, expert panel opinion and an international survey

scientific article published on 20 March 2017

Outpatient versus inpatient treatment in patients with pulmonary embolism: a meta-analysis.

scientific article published on 25 October 2012

PO-07 - Excluding pulmonary embolism in cancer patients using the Wells rule and age-adjusted D-dimer testing: an individual patient data meta-analysis.

scientific article

Patient outcomes after acute pulmonary embolism. A pooled survival analysis of different adverse events

scientific article published on 03 December 2009

Performance of a diagnostic algorithm based on a prediction rule, D-dimer and CT-scan for pulmonary embolism in patients with previous venous thromboembolism. A systematic review and meta-analysis.

scientific article published on 6 November 2014

Performance of five different bleeding-prediction scores in patients with acute pulmonary embolism

scientific article published on 20 June 2015

Performance of idarucizumab as antidote of dabigatran in daily clinical practice

scientific article published on 01 March 2019

Performance of the revised Geneva score in patients with a delayed suspicion of pulmonary embolism.

scientific article published on 13 February 2014

Persistence of oral anticoagulant treatment for atrial fibrillation in the Netherlands: A surveillance study

scientific article published on 24 October 2019

Persistence to direct oral anticoagulants for acute venous thromboembolism

scientific article published on 19 May 2018

Persistent dyspnea complaints at long-term follow-up after an episode of acute pulmonary embolism: results of a questionnaire.

scientific article published on 22 April 2008

Pharmacological properties of betrixaban.

scientific article

Physicians' management approach to an incidental pulmonary embolism: an international survey

scientific article published on 01 January 2013

Pitfalls in the diagnostic management of pulmonary embolism in pregnancy

scientific article published on March 2017

Predicting Post-Thrombotic Syndrome with Ultrasonographic Follow-Up after Deep Vein Thrombosis: A Systematic Review and Meta-Analysis

scientific article published on 04 July 2018

Predicting anticoagulant-related bleeding in patients with venous thromboembolism: a clinically oriented review

scientific article

Predicting recurrent pulmonary embolism and chronic thromboembolic pulmonary hypertension: one more way to skin the cat.

scientific article published on 25 May 2017

Prediction of bleeding events in patients with venous thromboembolism on stable anticoagulation treatment.

scientific article

Predictive value of venous thromboembolism (VTE)-BLEED to predict major bleeding and other adverse events in a practice-based cohort of patients with VTE: results of the XALIA study

scientific article published on 19 August 2018

Prevalence and potential determinants of exertional dyspnea after acute pulmonary embolism

scientific article published on 01 November 2010

Pulmonary embolism

Quality of life after pulmonary embolism as assessed with SF-36 and PEmb-QoL.

scientific article

Quality of life after pulmonary embolism: validation of the French version of the PEmb-QoL questionnaire.

scientific article

Quality of life after pulmonary embolism: validation of the PEmb-QoL Questionnaire.

scientific article published on 15 December 2009

Quality of life and functional limitations after pulmonary embolism and its prognostic relevance

scientific article published on 13 August 2019

Quality of life in long-term survivors of acute pulmonary embolism

scientific article published on 21 May 2010

Questioning the use of an age-adjusted D-dimer threshold to exclude venous thromboembolism: comment

scientific article published on 12 June 2018

Recent developments in the diagnosis and treatment of pulmonary embolism.

scientific article published on 19 August 2015

Recovery of right and left ventricular function after acute pulmonary embolism

scientific article published on 06 September 2011

Recurrence risk after anticoagulant treatment of limited duration for late, second venous thromboembolism.

scientific article published on 26 September 2014

Reliability of diagnosing incidental pulmonary embolism in cancer patients.

scientific article published on 19 June 2015

Reply: N-Terminal Pro-Brain Natriuretic Peptide Trial Design.

scientific article published on 2 March 2017

Right ventricular function and thrombus load in patients with pulmonary embolism and diagnostic delay

scientific article published on 01 February 2014

Risk of arterial cardiovascular events in patients after pulmonary embolism

scientific article published on 23 June 2009

Risk of atherothrombotic events in patients after proximal deep-vein thrombosis

scientific article published on 01 January 2016

Risk of recurrent venous thromboembolism and major hemorrhage in cancer-associated incidental pulmonary embolism among treated and untreated patients: a pooled analysis of 926 patients.

scientific article

Risk profile and clinical outcome of symptomatic subsegmental acute pulmonary embolism.

scientific article

Safety and feasibility of rivaroxaban in deferred workup of patients with suspected deep vein thrombosis

scientific article published on 01 June 2020

Safety of D-dimer as a stand-alone test for the exclusion of deep vein thrombosis compared to other strategies

scientific article published on 20 November 2018

Safety of ruling out acute pulmonary embolism by normal computed tomography pulmonary angiography in patients with an indication for computed tomography: systematic review and meta-analysis.

scientific article published on 22 June 2009

Safety of using the combination of the Wells rule and D-dimer test for excluding acute recurrent ipsilateral deep vein thrombosis

scientific article published on 02 July 2020

Seeking optimal treatment for phlegmasia cerulea dolens.

scientific article published on 5 February 2013

Selective D-dimer testing for the diagnosis of acute deep vein thrombosis: a validation study.

scientific article published in December 2013

Sex-specific differences in chronic thromboembolic pulmonary hypertension. Results from the European CTEPH registry

scientific article published on 24 September 2019

Sex-specific performance of pre-imaging diagnostic algorithms for pulmonary embolism.

scientific article published on 20 February 2018

Simplification of the revised Geneva score for assessing clinical probability of pulmonary embolism.

scientific article

Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study.

scientific article published on 23 May 2017

Smoking patterns in patients following a pulmonary embolism

scientific article published on 01 April 2009

Symptomatic subsegmental pulmonary embolism: to treat or not to treat?

scientific article published in December 2017

The HAS-BLED Score Identifies Patients with Acute Venous Thromboembolism at High Risk of Major Bleeding Complications during the First Six Months of Anticoagulant Treatment

scientific article published on 23 April 2015

The Post-COVID-19 Functional Status (PCFS) Scale: a tool to measure functional status over time after COVID-19

scientific article published on 12 May 2020

The YEARS algorithm for suspected pulmonary embolism:shorter visit time and reduced costs at the Emergency department.

scientific article published on 12 February 2018

The impact of post-pulmonary embolism syndrome and its possible determinants

scientific article published on 15 September 2018

The newer anticoagulants in thrombosis control in cancer patients

scientific article published on 24 April 2014

The original and simplified Wells rules and age-adjusted D-dimer testing to rule out pulmonary embolism: an individual patient data meta-analysis

scientific article

The physician's estimation 'alternative diagnosis is less likely than pulmonary embolism' in the Wells rule is dependent on the presence of other required items

scientific article published on 01 January 2008

The post-PE syndrome: a new concept for chronic complications of pulmonary embolism.

scientific article

Therapeutic management of acute pulmonary embolism

scientific article published on 5 June 2017

Thrombolysis for hemodynamically stable pulmonary embolism: time to close the book?

scientific article published on 24 October 2014

Timing of NT-pro-BNP sampling for predicting adverse outcome after acute pulmonary embolism.

scientific article published on 13 April 2010

To screen or not to screen for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism

scientific article published on 5 January 2017

Towards a tailored diagnostic standard for future diagnostic studies in pulmonary embolism: communication from the SSC of the ISTH.

scientific article published on 15 February 2017

Ultrasound-based diagnostic strategies for deep vein thrombosis.

scientific article published in March 2009

Update on techniques for the diagnosis of pulmonary embolism.

scientific article

Use of clinical prediction rules and D-dimer tests in the diagnostic management of pregnant patients with suspected acute pulmonary embolism.

scientific article

Utility of D-dimer testing in patients with clinically suspected pulmonary embolism and elevated C-reactive protein levels

scientific article published on 01 May 2008

Variable D-dimer thresholds for diagnosis of clinically suspected acute pulmonary embolism.

scientific article published in November 2013

Vitamin K Antagonists Compared to Low-Molecular-Weight Heparins for Treatment of Cancer-Associated Venous Thromboembolism: An Observational Study in Routine Clinical Practice. An Observational Study in Routine Clinical Practice

scientific article published on 4 October 2017

[Acute pulmonary embolism: beware of the wolf in sheep's clothing]

scientific article published on 01 January 2012

[Assessment of bleeding risk in patients with venous thromboembolism: we are still a long way from home].

scientific article

[Continued anticoagulation for unprovoked venous thromboembolism: guidance through the maze of recent studies]

scientific article published in January 2017

[Exclusion of deep-vein thrombosis and pulmonary embolism using clinical decision rules and D-dimer tests]

scientific article published on 01 January 2010

[Pulmonary embolism response teams: what is the added value for patients with acute pulmonary embolism?]

scientific article published in January 2017

[Thrombolysis not always necessary in patients with acute pulmonary embolism]

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