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List of works by Nehad M Alajez

Angiogenic Potential of Human Neonatal Foreskin Stromal Cells in the Chick Embryo Chorioallantoic Membrane Model.

scientific article published on 29 June 2015

Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells

scientific article

CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells.

scientific article

CUDC-907 Promotes Bone Marrow Adipocytic Differentiation Through Inhibition of Histone Deacetylase and Regulation of Cell Cycle.

scientific article

CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors

scientific article published on 11 April 2019

Cancer stem cells. From characterization to therapeutic implications

scientific article published on December 1, 2011

Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers.

scientific article published on 7 September 2017

Cloning and expression of human membrane-bound and soluble engineered T cell receptors for immunotherapy.

scientific article

Computational and Transcriptome Analyses Revealed Preferential Induction of Chemotaxis and Lipid Synthesis by SARS-CoV-2

scientific article published on 01 September 2020

Concurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo

scientific article published on 23 September 2019

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation

scientific article published on 21 March 2019

Enhanced efficacy of 5-fluorouracil in combination with a dual histone deacetylase and phosphatidylinositide 3-kinase inhibitor (CUDC-907) in colorectal cancer cells

scientific article published on January 2017

Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98.

scientific article

Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

scientific article

Epigenetic regulation of triple negative breast cancer (TNBC) by TGF-β signaling

scientific article published on 29 July 2021

Gene expression data analysis identifies multiple deregulated pathways in patients with asthma

article

Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer

scientific article

Gold-containing compound BDG-I inhibits the growth of A549 lung cancer cells through the deregulation of miRNA expression.

scientific article published on 6 June 2018

Identification of PBMC-based molecular signature associational with COVID-19 disease severity

scientific article published on 20 April 2021

In vitro differentiation of human skin-derived multipotent stromal cells into putative endothelial-like cells.

scientific article published on 27 January 2012

Integrated Study of Globally Expressed microRNAs in IL-1β-stimulated Human Osteoarthritis Chondrocytes and Osteoarthritis Relevant Genes: A Microarray and Bioinformatics Analysis.

scientific article published on 6 May 2016

Integrated Transcriptome and Pathway Analyses Revealed Multiple Activated Pathways in Breast Cancer

scientific article published on 18 September 2019

Integrated whole transcriptome and small RNA analysis revealed multiple regulatory networks in colorectal cancer

scientific article published on 14 July 2021

Large-Scale Analysis of Gene Expression Data Reveals a Novel Gene Expression Signature Associated with Colorectal Cancer Distant Recurrence

scientific article

Long non-coding RNA (lncRNA) transcriptional landscape in breast cancer identifies LINC01614 as non-favorable prognostic biomarker regulated by TGFβ and focal adhesion kinase (FAK) signaling

scientific article published on 24 June 2019

MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway

scientific article

MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1.

scientific article

MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer.

scientific article published on 4 July 2013

MicroRNA-301 mediates proliferation and invasion in human breast cancer.

scientific article

MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1.

scientific article published on 22 April 2016

MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP3.

scientific article published on 8 March 2017

Molecular profiling of ALDH1+ colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways.

scientific article

Molecular subtyping and functional validation of TTK, TPX2, UBE2C, and LRP8 in sensitivity of TNBC to paclitaxel

scientific article published on 26 January 2021

Multiple intracellular signaling pathways orchestrate adipocytic differentiation of human bone marrow stromal stem cells

scientific article published on 3 January 2018

Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B.

scientific article

Noncoding RNAs as potential mediators of resistance to cancer immunotherapy

scientific article published on 14 November 2019

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells

scientific article published on 22 August 2019

Oxygen-independent degradation of HIF-alpha via bioengineered VHL tumour suppressor complex.

scientific article published on April 2009

PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer

scientific article published on 25 July 2019

Pembrolizumab Interferes with the Differentiation of Human FOXP3+-Induced T Regulatory Cells, but Not with FOXP3 Stability, through Activation of mTOR

scientific article published on 04 December 2019

Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells

scientific article published on 17 September 2013

Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response

scientific article published on 07 July 2020

Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells

scientific article published on 21 January 2020

Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity.

scientific article

Runt-related Transcription Factor 1 (RUNX1T1) Suppresses Colorectal Cancer Cells Through Regulation of Cell Proliferation and Chemotherapeutic Drug Resistance

scientific article published on October 2016

SERPINB2 is a novel TGFβ-responsive lineage fate determinant of human bone marrow stromal cells

scientific article published on 7 September 2017

SOX4: Epigenetic regulation and role in tumorigenesis

scientific article published on 02 July 2019

Significance of BMI1 and FSCN1 expression in colorectal cancer.

scientific article published on July 2016

Significance of Plk1 regulation by miR-100 in human nasopharyngeal cancer.

scientific article published in May 2010

Significance of dysregulated metadherin and microRNA-375 in head and neck cancer.

scientific article

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19

scientific article published on 29 October 2020

Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy

scientific article published on 25 January 2021

Stem cell library screen identified ruxolitinib as regulator of osteoblastic differentiation of human skeletal stem cells

scientific article published on 21 November 2018

TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton.

scientific article published on 15 February 2018

Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy.

scientific article published on 3 July 2009

Targeting uroporphyrinogen decarboxylase for head and neck cancer treatment.

scientific article published on 4 April 2013

Therapeutic efficacy of seliciclib in combination with ionizing radiation for human nasopharyngeal carcinoma.

scientific article

Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immune system through bone marrow transduction and immune reconstitution.

scientific article published on 3 March 2005

Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq

scientific article published on 14 September 2021

Transcriptomic Analyses Revealed Systemic Alterations in Gene Expression in Circulation and Tumor Microenvironment of Colorectal Cancer Patients

scientific article published on 11 December 2019

Transcriptomic Profiling of Tumor-Infiltrating CD4+TIM-3+ T Cells Reveals Their Suppressive, Exhausted, and Metastatic Characteristics in Colorectal Cancer Patients

scientific article published on 06 February 2020

Transgelin is a TGFβ-inducible gene that regulates osteoblastic and adipogenic differentiation of human skeletal stem cells through actin cytoskeleston organization.

scientific article published on 04 August 2016

Whole genome mRNA expression profiling revealed multiple deregulated pathways in stromal vascular fraction from erectile dysfunction patients

scientific article published on 23 November 2018

microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection.

scientific article published on 16 May 2016

microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells

scientific article

microRNAs as regulators of adipogenic differentiation of mesenchymal stem cells.

scientific article

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