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List of works by Daniel B Lipka

3,4-Diarylmaleimides-a novel class of kinase inhibitors-effectively induce apoptosis in FLT3-ITD-dependent cells

scientific article published on 01 September 2011

Addition of rituximab to standard therapy improves response rate and progression-free survival in relapsed or refractory thrombotic thrombocytopenic purpura and autoimmune haemolytic anaemia.

scientific article

AmpliconDesign - an interactive web server for the design of high-throughput targeted DNA methylation assays

scientific article published on 24 October 2020

Author Correction: Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals

scientific article published on 01 August 2019

Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia

scientific article published on 24 January 2019

CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia.

scientific article published on 5 May 2016

Clinically relevant doses of FLT3-kinase inhibitors quizartinib and midostaurin do not impair T-cell reactivity and function.

scientific article published on 14 March 2014

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

scientific article

Development of tyrosine kinase inhibitors for hematologic neoplasms. FLT3 and JAK2 as therapeutic targets

scientific article published in January 2008

Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha

scientific article published on 02 April 2019

Dissection of CD20 regulation in lymphoma using RNAi

scientific article published on 18 August 2016

Dysregulated serum response factor triggers formation of hepatocellular carcinoma

scientific article

Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia

scientific article

Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia

scientific article published on 18 February 2016

Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals

scientific article

Epo-induced erythroid maturation is dependent on Plcγ1 signaling.

scientific article published on 14 November 2014

Erratum: DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

scientific article published in October 2017

FLT3 as a therapeutic target in AML: still challenging after all these years

scientific article (publication date: 12 August 2010)

From Basic Knowledge to Effective Therapies

scientific article published on 01 December 2018

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.

scientific article published on 19 December 2017

Germline SDHB-inactivating mutation in gastric spindle cell sarcoma

scientific article published on 05 June 2020

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

scientific article published on 10 May 2019

Histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target

scientific article published on 09 June 2019

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells

scientific article

Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing

scientific article

Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.

scientific article published on 21 August 2014

Impact of DNA methylation programming on normal and pre-leukemic hematopoiesis

scientific article published on 27 September 2017

Integrating Patient Data Into Skin Cancer Classification Using Convolutional Neural Networks: Systematic Review

publication published on 02 July 2021

Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma

scientific article published on 28 February 2019

International consensus definition of DNA methylation subgroups in juvenile myelomonocytic leukemia

scientific article published on 02 November 2020

Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer.

scientific article published on 24 July 2014

LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells

scientific article published on 07 November 2018

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

scientific article published on 18 March 2020

Molecular tumor classification using DNA methylome analysis

scientific article published on 13 July 2020

Nilotinib shows prolonged intracellular accumulation upon pulse-exposure: a novel mechanism for induction of apoptosis in CML cells ⬇️

scientific article published on December 12, 2012

Prolonged cellular midostaurin retention suggests potential alternative dosing strategies for FLT3-ITD-positive leukemias.

scientific article published on 3 May 2016

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

scientific article published on 19 December 2017

Substituted purine and 7-deazapurine compounds as modulators of epigenetic enzymes: a patent evaluation (WO2012075381)

scientific article published on 01 March 2013

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.

scientific article

Wild-type JAK2 secondary acute erythroleukemia developing after JAK2-V617F-mutated primary myelofibrosis.

scientific article published on 28 August 2009

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