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List of works by Shaun M K McKinnie

Algal Neurotoxin Biosynthesis Repurposes the Terpene Cyclase Structural Fold Into an N -prenyltransferase

Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into an N-prenyltransferase

scientific article published on 26 May 2020

Angiotensin-Converting Enzyme 2 Metabolizes and Partially Inactivates Pyr-Apelin-13 and Apelin-17: Physiological Effects in the Cardiovascular System

scientific article

Biosynthesis of l ‐4‐Chlorokynurenine, an Antidepressant Prodrug and a Non‐Proteinogenic Amino Acid Found in Lipopeptide Antibiotics

Biosynthesis of l-4-Chlorokynurenine, an Antidepressant Prodrug and a Non-Proteinogenic Amino Acid Found in Lipopeptide Antibiotics

scientific article published on 13 May 2019

Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom.

scientific article published in September 2018

Cariogenic Streptococcus mutans Produces Tetramic Acid Strain-Specific Antibiotics That Impair Commensal Colonization ⬇️

scientific article published on 10 January 2020

Characterization and Biochemical Assays of Streptomyces Vanadium-Dependent Chloroperoxidases. ⬇️

scientific article published on 2 April 2018

Comparative Genomics and Metabolomics in the Genus Nocardia

scientific article published on 02 June 2020

Correction to Organohalogens Naturally Biosynthesized in Marine Environments and Produced As Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics

scientific article published on 19 June 2018

Differential response of orthologous L,L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds.

scientific article published on 9 November 2013

Investigating the Role of Vanadium-Dependent Haloperoxidase Enzymology in Microbial Secondary Metabolism and Chemical Ecology

scientific article published in 2021

Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues.

scientific article published on July 2013

Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage

scientific article published on 16 September 2019

Meroterpenoid natural products from Streptomyces bacteria - the evolution of chemoenzymatic syntheses

scientific article published on 30 June 2020

Nonlinear Biosynthetic Assembly of Alpiniamide by a Hybrid cis/trans-AT PKS-NRPS

scientific article published on 06 April 2020

Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics.

scientific article

Plasma kallikrein cleaves and inactivates apelin-17: Palmitoyl- and PEG-extended apelin-17 analogs as metabolically stable blood pressure-lowering agents

scientific article published on 18 January 2019

Scalable Biosynthesis of the Seaweed Neurochemical, Kainic Acid

scientific article published on 10 May 2019

Scalable Biosynthesis of the Seaweed Neurochemical, Kainic Acid

scientific article published in 2019

Solid-supported synthesis and biological evaluation of the lantibiotic peptide bis(desmethyl) lacticin 3147 A2.

scientific article

Synthesis, bioactivity, and enzymatic modification of antibacterial thiotetromycin derivatives

scientific article published on 01 March 2019

Synthetic Modification within the "RPRL" Region of Apelin Peptides: Impact on Cardiovascular Activity and Stability to Neprilysin and Plasma Degradation.

scientific article

Targeting the apelin pathway as a novel therapeutic approach for cardiovascular diseases

scientific article published on 04 November 2016

The Metalloprotease Neprilysin Degrades and Inactivates Apelin Peptides.

scientific article published on 5 July 2016

The Synthesis of Active and Stable Diaminopimelate Analogues of the Lantibiotic Peptide Lactocin S

scientific article published on 24 January 2012

Total Enzyme Syntheses of Napyradiomycins A1 and B1

scientific article published on 14 December 2018

Total Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural Products

scientific article published on 23 July 2018

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