List of works - Eric S Mullins

Early detection of thrombin activity in neuroinflammatory disease

scientific article

Elimination of the fibrinogen integrin αβ-binding motif improves renal pathology in mice with sickle cell anemia

scientific article published on 01 May 2019

Extended half-life pegylated, full-length recombinant factor VIII for prophylaxis in children with severe haemophilia A.

scientific article published on 27 November 2016

Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice

scientific article

Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain.

scientific article published on 16 October 2008

Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice

scientific article published on June 2016

Long-term safety and efficacy results from the phase 3b, open-label, multicentre Continuation study of rurioctocog alfa pegol for prophylaxis in previously treated patients with severe haemophilia A

scientific article published on 28 June 2020

Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense.

scientific article

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.

scientific article

Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation

scientific article published on 17 May 2019

Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease

scientific article

Real-world experience with use of Antihemophilic Factor (Recombinant), PEGylated for prophylaxis in severe haemophilia A.

scientific article

Subcutaneous diphtheria and tetanus vaccines in children with haemophilia: A pilot study and review of the literature.

scientific article published on 6 August 2017

Successful management of concurrent acquired hemophilia A and a lupus anticoagulant in a pediatric hematopoietic stem cell transplant patient.

scientific article published on 12 January 2018

Synthesis and anticoagulant activity of polyureas containing sulfated carbohydrates

scientific article

The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A ⬇️

scientific article published on March 24, 2011

Thrombin drives tumorigenesis in colitis-associated colon cancer

scientific article

Thrombin promotes diet-induced obesity through fibrin-driven inflammation

scientific article

Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain ⬇️

scientific article published on July 25, 2011

Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion

scientific article

Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells

scientific article published on 21 March 2017

Whole-exome analysis of adolescents with low VWF and heavy menstrual bleeding identifies novel genetic associations

scientific article published on 01 January 2022

List of works by Eric S Mullins

Early detection of thrombin activity in neuroinflammatory disease

Elimination of the fibrinogen integrin αβ-binding motif improves renal pathology in mice with sickle cell anemia

Extended half-life pegylated, full-length recombinant factor VIII for prophylaxis in children with severe haemophilia A.

Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice

Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain.

Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice

Long-term safety and efficacy results from the phase 3b, open-label, multicentre Continuation study of rurioctocog alfa pegol for prophylaxis in previously treated patients with severe haemophilia A

Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense.

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.

Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation

Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease

Real-world experience with use of Antihemophilic Factor (Recombinant), PEGylated for prophylaxis in severe haemophilia A.

Subcutaneous diphtheria and tetanus vaccines in children with haemophilia: A pilot study and review of the literature.

Successful management of concurrent acquired hemophilia A and a lupus anticoagulant in a pediatric hematopoietic stem cell transplant patient.

Synthesis and anticoagulant activity of polyureas containing sulfated carbohydrates

The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A ⬇️

Thrombin drives tumorigenesis in colitis-associated colon cancer

Thrombin promotes diet-induced obesity through fibrin-driven inflammation

Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain ⬇️

Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion

Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells

Whole-exome analysis of adolescents with low VWF and heavy menstrual bleeding identifies novel genetic associations