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List of works by Jianxin Fu

Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice

scientific article published on 04 May 2016

Core 1-derived mucin-type O-glycosylation protects against spontaneous gastritis and gastric cancer

scientific article published on 01 January 2020

Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis

scientific article published on 26 November 2018

Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

scientific article

Discordance between changes in the gut microbiota and pathogenicity in a mouse model of spontaneous colitis.

scientific article

Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice

scientific article published on 04 August 2018

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

scientific article

Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma

scientific article published on 24 October 2013

Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice

scientific article

Loss of intestinal O-glycans promotes spontaneous duodenal tumors

scientific article published on 26 May 2016

Loss of mucin-type O-glycans impairs the integrity of the glomerular filtration barrier in the mouse kidney.

scientific article published on 25 August 2017

Mucin-type O-glycosylation is critical for vascular integrity

scientific article

O-glycans direct selectin ligands to lipid rafts on leukocytes.

scientific article published on 29 June 2015

Plasma soluble podoplanin is a novel marker for the diagnosis of tumor occurrence and metastasis.

scientific article published on 21 December 2017

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life.

scientific article published on January 2014

Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

scientific article

Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets

scientific article

Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells.

scientific article published on 17 July 2017

Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking

scientific article published on 26 July 2018

The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

scientific article published on 27 October 2014