List of works - Tony Lahoutte

(18)F-nanobody for PET imaging of HER2 overexpressing tumors.

scientific article published on 23 January 2016

123I-2-iodo-tyrosine, a new tumour imaging agent: human biodistribution, dosimetry and initial clinical evaluation in glioma patients.

scientific article

131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment

scientific article published on 27 July 2017

99mTc-cAbVCAM1-5 imaging is a sensitive and reproducible tool for the detection of inflamed atherosclerotic lesions in mice

scientific article published on 25 August 2014

A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.

scientific article published on 9 November 2017

A standardized method for in vivo mouse pancreas imaging and semiquantitative β cell mass measurement by dual isotope SPECT.

scientific article published on February 2015

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model

scientific article published on 21 February 2017

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model

scientific article published on 9 June 2017

Camelid reporter gene imaging: a generic method for in vivo cell tracking

scientific article

Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages

scientific article published on 01 October 2019

D- and L-[123I]-2-I-phenylalanine show a long tumour retention compared with D- and L-[123I]-2-I-tyrosine in R1M rhabdomyosarcoma tumour-bearing Wag/Rij rats

scientific article published on 01 July 2007

Dynamic bioluminescence imaging for quantitative tumour burden assessment using IV or IP administration of D: -luciferin: effect on intensity, time kinetics and repeatability of photon emission.

scientific article published on 4 January 2008

Evaluation of Antiatherogenic Properties of Ezetimibe Using 3H-Labeled Low-Density-Lipoprotein Cholesterol and 99mTc-cAbVCAM1-5 SPECT in ApoE-/- Mice Fed the Paigen Diet

scientific article published on 9 March 2017

Evaluation of [(99m)Tc]Radiolabeled Macrophage Mannose Receptor-Specific Nanobodies for Targeting of Atherosclerotic Lesions in Mice.

scientific article published on 5 September 2017

Evaluation of an Anti-HER2 Nanobody Labeled with 225Ac for Targeted α-Particle Therapy of Cancer

scientific article published on 5 March 2018

Evaluation of the radiation dose in micro-CT with optimization of the scan protocol.

scientific article published on July 2010

Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional Cis-regulatory motifs that enable efficient cardiac gene therapy

scientific article published on 8 September 2014

Improved Debulking of Peritoneal Tumor Implants by Near-Infrared Fluorescent Nanobody Image Guidance in an Experimental Mouse Model.

scientific article published on 31 October 2017

Improved tumor targeting of anti-HER2 nanobody through N-succinimidyl 4-guanidinomethyl-3-iodobenzoate radiolabeling

scientific article

In search of an improved injection technique for the clinical application of spermatogonial stem cell transplantation.

scientific article published on 15 December 2016

In vitro analysis and in vivo tumor targeting of a humanized, grafted nanobody in mice using pinhole SPECT/micro-CT.

scientific article published on 16 June 2010

Intra-individual comparison of the human biodistribution and dosimetry of the D and L isomers of 2-[123I]iodo-phenylalanine

scientific article published on 01 October 2007

Labeling of Anti-HER2 Nanobodies with Astatine-211: Optimization and the Effect of Different Coupling Reagents on Their in Vivo Behavior

scientific article published on 03 July 2019

Molecular imaging using Nanobodies: a case study.

scientific article published in January 2012

Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis.

scientific article published on 31 March 2014

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

scientific article published on 02 October 2014

Nanobodies as tools for in vivo imaging of specific immune cell types

scientific article published on 15 April 2010

Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages.

scientific article

Next-generation muscle-directed gene therapy by in silico vector design

scientific article published in Nature Communications

Non-Invasive Imaging of Amyloid Deposits in a Mouse Model of AGel Using (99m)Tc-Modified Nanobodies and SPECT/CT.

scientific article

Notch signaling as gatekeeper of rat acinar-to-beta-cell conversion in vitro.

scientific article published on 27 January 2009

Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer.

scientific article published on 21 July 2012

PET Imaging of Macrophage Mannose Receptor-Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments

scientific article published on 11 June 2015

Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.

scientific article

Preclinical Targeted α- and β--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies

scientific article published on 21 April 2020

Preliminary in vivo evaluation of [131I]-2-iodo-D-phenylalanine as a potential radionuclide therapeutic agent in R1M-fluc rhabdomyosarcoma tumor-bearing NuNu mice using bioluminescent imaging.

scientific article published in April 2010

Quality control of micro-computed tomography systems

scientific article published on 11 March 2010

Radiolabeled mannosylated dextran derivatives bearing an NIR-fluorophore for sentinel lymph node imaging

scientific article published on 14 October 2014

Rapid hepatic clearance of 99mTc-TMEOP: a new candidate for myocardial perfusion imaging.

scientific article published on 29 December 2010

SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis.

scientific article published on 27 February 2013

Serial Semiquantitative Imaging of Brain Damage Using Micro-SPECT and Micro-CT After Endothelin-1–Induced Transient Focal Cerebral Ischemia in Rats ⬇️

scientific article published on November 2, 2011

Site-Specific Labeling of His-Tagged Nanobodies with 99mTc: A Practical Guide

scientific article published on 01 January 2012

Size and affinity kinetics of nanobodies influence targeting and penetration of solid tumours

scientific article published on 14 November 2019

Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.

scientific article published on 5 May 2016

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

scientific article published on 25 October 2016

Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors

scientific article published on 15 October 2019

Targeted alpha therapy using short-lived alpha-particles and the promise of nanobodies as targeting vehicle.

scientific article published on 04 May 2016

Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

scientific article published on 22 January 2016

The Road to Personalized Myeloma Medicine: Patient-specific Single-domain Antibodies for Anti-idiotypic Radionuclide Therapy

scientific article published in January 2022

Theranostic Radiolabeled Anti-CD20 sdAb for Targeted Radionuclide Therapy of Non-Hodgkin Lymphoma.

scientific article published on 20 October 2017

Translating Molecular Imaging of the Vulnerable Plaque-a Vulnerable Project?

scientific article published on 27 November 2017

List of works by Tony Lahoutte

(18)F-nanobody for PET imaging of HER2 overexpressing tumors.

123I-2-iodo-tyrosine, a new tumour imaging agent: human biodistribution, dosimetry and initial clinical evaluation in glioma patients.

131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment

99mTc-cAbVCAM1-5 imaging is a sensitive and reproducible tool for the detection of inflamed atherosclerotic lesions in mice

A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.

A standardized method for in vivo mouse pancreas imaging and semiquantitative β cell mass measurement by dual isotope SPECT.

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model

AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model

Camelid reporter gene imaging: a generic method for in vivo cell tracking

Clinical Translation of [68Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages

D- and L-[123I]-2-I-phenylalanine show a long tumour retention compared with D- and L-[123I]-2-I-tyrosine in R1M rhabdomyosarcoma tumour-bearing Wag/Rij rats

Dynamic bioluminescence imaging for quantitative tumour burden assessment using IV or IP administration of D: -luciferin: effect on intensity, time kinetics and repeatability of photon emission.

Evaluation of Antiatherogenic Properties of Ezetimibe Using 3H-Labeled Low-Density-Lipoprotein Cholesterol and 99mTc-cAbVCAM1-5 SPECT in ApoE-/- Mice Fed the Paigen Diet

Evaluation of [(99m)Tc]Radiolabeled Macrophage Mannose Receptor-Specific Nanobodies for Targeting of Atherosclerotic Lesions in Mice.

Evaluation of an Anti-HER2 Nanobody Labeled with 225Ac for Targeted α-Particle Therapy of Cancer

Evaluation of the radiation dose in micro-CT with optimization of the scan protocol.

Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional Cis-regulatory motifs that enable efficient cardiac gene therapy

Improved Debulking of Peritoneal Tumor Implants by Near-Infrared Fluorescent Nanobody Image Guidance in an Experimental Mouse Model.

Improved tumor targeting of anti-HER2 nanobody through N-succinimidyl 4-guanidinomethyl-3-iodobenzoate radiolabeling

In search of an improved injection technique for the clinical application of spermatogonial stem cell transplantation.

In vitro analysis and in vivo tumor targeting of a humanized, grafted nanobody in mice using pinhole SPECT/micro-CT.

Intra-individual comparison of the human biodistribution and dosimetry of the D and L isomers of 2-[123I]iodo-phenylalanine

Labeling of Anti-HER2 Nanobodies with Astatine-211: Optimization and the Effect of Different Coupling Reagents on Their in Vivo Behavior

Molecular imaging using Nanobodies: a case study.

Molecular imaging with macrophage CRIg-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis.

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

Nanobodies as tools for in vivo imaging of specific immune cell types

Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages.

Next-generation muscle-directed gene therapy by in silico vector design

Non-Invasive Imaging of Amyloid Deposits in a Mouse Model of AGel Using (99m)Tc-Modified Nanobodies and SPECT/CT.

Notch signaling as gatekeeper of rat acinar-to-beta-cell conversion in vitro.

Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer.

PET Imaging of Macrophage Mannose Receptor-Expressing Macrophages in Tumor Stroma Using 18F-Radiolabeled Camelid Single-Domain Antibody Fragments

Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma.

Preclinical Targeted α- and β--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies

Preliminary in vivo evaluation of [131I]-2-iodo-D-phenylalanine as a potential radionuclide therapeutic agent in R1M-fluc rhabdomyosarcoma tumor-bearing NuNu mice using bioluminescent imaging.

Quality control of micro-computed tomography systems

Radiolabeled mannosylated dextran derivatives bearing an NIR-fluorophore for sentinel lymph node imaging

Rapid hepatic clearance of 99mTc-TMEOP: a new candidate for myocardial perfusion imaging.

SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritis.

Serial Semiquantitative Imaging of Brain Damage Using Micro-SPECT and Micro-CT After Endothelin-1–Induced Transient Focal Cerebral Ischemia in Rats ⬇️

Site-Specific Labeling of His-Tagged Nanobodies with 99mTc: A Practical Guide

Size and affinity kinetics of nanobodies influence targeting and penetration of solid tumours

Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.

Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors

Targeted alpha therapy using short-lived alpha-particles and the promise of nanobodies as targeting vehicle.

Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

The Road to Personalized Myeloma Medicine: Patient-specific Single-domain Antibodies for Anti-idiotypic Radionuclide Therapy

Theranostic Radiolabeled Anti-CD20 sdAb for Targeted Radionuclide Therapy of Non-Hodgkin Lymphoma.

Translating Molecular Imaging of the Vulnerable Plaque-a Vulnerable Project?