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List of works by Junxuan Lü

1,2,3,4,6-Penta-O-galloly-beta-D-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α and signaling in LNCaP prostate cancer cells.

scientific article published on January 2010

A new chalcone derivative (E)-3-(4-methoxyphenyl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one suppresses prostate cancer involving p53-mediated cell cycle arrests and apoptosis

scientific article published on September 1, 2012

A novel sulindac derivative lacking cyclooxygenase-inhibitory activities suppresses carcinogenesis in the transgenic adenocarcinoma of mouse prostate model.

scientific article published on 29 June 2010

A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo.

scientific article

An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis.

scientific article published on 15 June 2006

Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds.

scientific article

Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose.

scientific article

Cancer Chemoprevention with Korean Angelica: Active Compounds, Pharmacokinetics, and Human Translational Considerations.

scientific article

Cancer chemoprevention research with selenium in the post-SELECT era: Promises and challenges

scientific article published on 23 November 2015

Cellular and metabolic effects of triphenylselenonium chloride in a mammary cell culture model ⬇️

scientific article published on March 1, 1995

Chemopreventive Effects of Korean Angelica versus Its Major Pyranocoumarins on Two Lineages of Transgenic Adenocarcinoma of Mouse Prostate Carcinogenesis

scientific article

Chemopreventive effect of Korean Angelica root extract on TRAMP carcinogenesis and integrative "omic" profiling of affected neuroendocrine carcinomas

scientific article published on 12 October 2014

Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53-deficiency-driven castration-resistant prostate cancer

scientific article published on 19 March 2016

Cytochrome P450 Isoforms in the Metabolism of Decursin and Decursinol Angelate from Korean Angelica.

scientific article published on 22 September 2015

Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells.

scientific article

Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells.

scientific article published on May 2007

Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice

scientific article

Dissociation of the genotoxic and growth inhibitory effects of selenium ⬇️

scientific article published on July 17, 1995

Galbanic Acid Isolated from Ferula assafoetida Exerts In Vivo Anti-tumor Activity in Association with Anti-angiogenesis and Anti-proliferation ⬇️

scientific article published on November 10, 2010

Galbanic acid decreases androgen receptor abundance and signaling and induces G1 arrest in prostate cancer cells ⬇️

scientific article published on May 9, 2011

Gene expression changes associated with chemically induced rat mammary carcinogenesis ⬇️

scientific article published on 01 October 1997

Gene expression signatures associated with suppression of TRAMP prostate carcinogenesis by a kavalactone-rich Kava fraction

scientific article published on 3 February 2016

Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth

scientific article

In vitro metabolism of pyranocoumarin isomers decursin and decursinol angelate by liver microsomes from man and rodents.

scientific article published on 11 September 2013

Involvement of autophagy induction in penta-1,2,3,4,6-O-galloyl-β-D-glucose-induced senescence-like growth arrest in human cancer cells

scientific article

Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.

scientific article

Ka-mi-kae-kyuk-tang oriental herbal cocktail attenuates cyclophosphamide-induced leukopenia side effects in mouse ⬇️

scientific article published on March 11, 2011

Kava blocks 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in association with reducing O6-methylguanine DNA adduct in A/J mice

scientific article published on January 2014

Lobe-specific proteome changes in the dorsal-lateral and ventral prostate of TRAMP mice versus wild-type mice

scientific article

Lobe‐specific lineages of carcinogenesis in the transgenic adenocarcinoma of mouse prostate and their responses to chemopreventive selenium ⬇️

scientific article published on February 25, 2011

Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice

scientific article published on 01 January 2011

Methyl selenium-induced vascular endothelial apoptosis is executed by caspases and principally mediated by p38 MAPK pathway

scientific article published on 01 January 2004

Methylseleninic Acid Superactivates p53-Senescence Cancer Progression Barrier in Prostate Lesions of Pten-Knockout Mouse

scientific article

Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density

scientific article published on 01 January 2008

Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells.

scientific article published in March 2005

Methylseleninic acid suppresses pancreatic cancer growth involving multiple pathways.

scientific article published on 21 January 2014

Mouse prostate proteome changes induced by oral pentagalloylglucose treatment suggest targets for cancer chemoprevention.

scientific article

Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds

scientific article published on 01 June 2011

Optimizing live-animal bioluminescence imaging prediction of tumor burden in human prostate cancer xenograft models in SCID-NSG mice

scientific article published on 08 April 2019

Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo.

scientific article published on September 2008

Penta-O-galloyl-beta-D-glucose induces G1 arrest and DNA replicative S-phase arrest independently of cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple n

scientific article published on 01 September 2010

Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells.

scientific article

Penta‐1,2,3,4,6‐O‐galloyl‐beta‐D‐glucose induces senescence‐like terminal S‐phase arrest in human hepatoma and breast cancer cells ⬇️

scientific article published on February 11, 2011

Persistent p21Cip1 induction mediates G(1) cell cycle arrest by methylseleninic acid in DU145 prostate cancer cells.

scientific article published on May 2010

Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells.

scientific article

Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer.

scientific article published on January 2006

Preparation of penta-O-galloyl-β-d-glucose from tannic acid and plasma pharmacokinetic analyses by liquid–liquid extraction and reverse-phase HPLC ⬇️

scientific article published on September 29, 2010

Proteomic and transcriptomic profiling of Pten gene-knockout mouse model of prostate cancer

scientific article published on 12 March 2020

Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model.

scientific article

Pyranocoumarin Tissue Distribution, Plasma Metabolome and Prostate Transcriptome Impacts of Sub-Chronic Exposure to Korean Angelica Supplement in Mice

scientific article published on April 2016

Quantitative Determination of Decursin, Decursinol Angelate, and Decursinol in Mouse Plasma and Tumor Tissue Using Liquid-Liquid Extraction and HPLC ⬇️

scientific article published on November 24, 2011

Rasmay mediate mammary cancer promotion by high fat ⬇️

scientific article published on January 1, 1995

Role of P53-Senescence Induction in Suppression of LNCaP Prostate Cancer Growth by Cardiotonic Compound Bufalin

scientific article published on 30 August 2018

Selenite-induced p53 Ser-15 phosphorylation and caspase-mediated apoptosis in LNCaP human prostate cancer cells.

scientific article published on July 2004

Single Oral Dose Pharmacokinetics of Decursin, Decursinol Angelate, and Decursinol in Rats ⬇️

scientific article published on January 30, 2013

Single oral dose pharmacokinetics of decursin and decursinol angelate in healthy adult men and women.

scientific article

Superior in vivo inhibitory efficacy of methylseleninic acid against human prostate cancer over selenomethionine or selenite.

scientific article published on 28 February 2008

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

scientific article published on January 2010

Tanshinones from Chinese Medicinal Herb Danshen (Salvia miltiorrhiza Bunge) Suppress Prostate Cancer Growth and Androgen Receptor Signaling ⬇️

scientific article published on January 27, 2012

Tanshinones: Sources, Pharmacokinetics and Anti-Cancer Activities ⬇️

scientific article published on October 22, 2012

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