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List of works by Itziar Otano

Adeno-associated virus liver transduction efficiency measured by in vivo [18F]FHBG positron emission tomography imaging in rodents and nonhuman primates.

scientific article published on 6 April 2011

CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs

scientific article published on 15 November 2018

CD137 (4-1BB) costimulation of CD8<sup>+</sup> T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation

scientific article published on 15 December 2021

Characterization of woodchuck apolipoprotein A-I: a new tool for drug delivery and identification of altered isoforms in the woodchuck chronic hepatitis model.

scientific article published on 22 April 2011

Complementary Effects of Interleukin-15 and Alpha Interferon Induce Immunity in Hepatitis B Virus Transgenic Mice.

scientific article published on 20 July 2016

Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer

scientific article

Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host.

scientific article published on 20 July 2016

Expansion of Tumor-Infiltrating CD8+ T cells Expressing PD-1 Improves the Efficacy of Adoptive T-cell Therapy.

scientific article published on 18 May 2017

Gene therapy for viral hepatitis.

scientific article published on December 2006

Identification of CD4+ and CD8+ T cell epitopes of woodchuck hepatitis virus core and surface antigens in BALB/c mice.

scientific article published on July 2010

Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

scientific article published on 27 June 2019

Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells

scientific article published on 21 November 2019

Liver-directed gene therapy of chronic hepadnavirus infection using interferon alpha tethered to apolipoprotein A-I.

scientific article published on 12 March 2015

Modulation of regulatory T-cell activity in combination with interleukin-12 increases hepatic tolerogenicity in woodchucks with chronic hepatitis B.

scientific article

Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver

scientific article published on 16 August 2018

Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

scientific article published on 01 May 2019

Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.

scientific article published on 09 September 2009

TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis

scientific article

Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12.

scientific article

Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12.

scientific article published on 30 December 2008

Treatment of pancreatic cancer with an oncolytic adenovirus expressing interleukin-12 in Syrian hamsters.

scientific article

Twists and turns to translating 4-1BB cancer immunotherapy

scientific article published on 01 June 2019

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