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List of works by Thomas Grunewald

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

scientific article published in 2023

Acute stress enhances the expression of neuroprotection- and neurogenesis-associated genes in the hippocampus of a mouse restraint model

scientific article published on 06 February 2016

Allogeneic stem cell transplantation for patients with advanced rhabdomyosarcoma: a retrospective assessment

scientific article published on 22 October 2013

An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein

scientific article published in January 2015

Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers

scientific article published on December 2013

Are EWSR1-NFATc2-positive sarcomas really Ewing sarcomas?

scientific article published on 12 June 2018

Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP

scientific article published on August 2009

Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite

scientific article

Defining the role of TRIP6 in cell physiology and cancer.

scientific article published on December 2011

Editorial: Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges

scientific article published on 18 February 2016

Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis.

scientific article published on February 2016

First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.

scientific article published on 4 May 2013

First report of ectopic ACTH syndrome and PTHrP-induced hypercalcemia due to a hepatoblastoma in a child.

scientific article published on 4 February 2010

First report of effective and feasible treatment of multifocal lymphangiomatosis (Gorham-Stout) with bevacizumab in a child.

scientific article published on 6 July 2010

Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma

scientific article published on 04 December 2018

Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility

scientific article published in Nature Communications

Hepatitis B virus large surface protein is priming for hepatocellular carcinoma development via induction of cytokinesis failure

article

High STEAP1 expression is associated with improved outcome of Ewing's sarcoma patients

scientific article published on 08 February 2012

Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma

scientific article published on 04 February 2020

Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma

scientific article published on 29 November 2019

Interaction between somatic mutations and germline variants contributes to clinical heterogeneity in cancer

scientific article published on 06 November 2019

LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia

scientific article published in July 2014

LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression

scientific article published on 10 June 2015

Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration.

scientific article published in June 2014

Lysophosphatidic acid (LPA) signalling in cell migration and cancer invasion: a focussed review and analysis of LPA receptor gene expression on the basis of more than 1700 cancer microarrays.

scientific article published on 03 June 2013

Mesenchymal stromal cells for treatment of steroid-refractory GvHD: a review of the literature and two pediatric cases.

scientific article

Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours

scientific article published on 12 July 2019

Next steps in preventing Ewing sarcoma progression

scientific article

Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer.

scientific article

Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma

scientific article

Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma

scientific article published on 15 May 2020

Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisation

scientific article

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

scientific article published in 2022

Pan-Cancer Analysis of Mitochondria Chaperone-Client Co-Expression Reveals Chaperone Functional Partitioning

scientific article published on 30 March 2020

Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo.

scientific article published on 17 January 2017

Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation.

scientific article

Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma

scientific article published on 23 November 2020

SOX6: a double-edged sword for Ewing sarcoma

scientific article published on 14 July 2020

Sarcoma classification by DNA methylation profiling

scientific article published on 21 January 2021

Sarcoma treatment in the era of molecular medicine

scientific article published on 13 October 2020

Sclerosing epithelioid fibrosarcoma of the bone: a case report of high resistance to chemotherapy and a survey of the literature

scientific article

Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells.

scientific article

Systematic identification of cancer-specific MHC-binding peptides with RAVEN

scientific article published on 23 July 2018

Targeted therapeutics in treatment of children and young adults with solid tumors: an expert survey and review of the literature.

scientific article published on 20 April 2012

The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer ⬇️

scientific article

The STEAP protein family: versatile oxidoreductases and targets for cancer immunotherapy with overlapping and distinct cellular functions.

scientific article published on 24 September 2012

The Zyxin-related protein thyroid receptor interacting protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growth

scientific article published on 18 September 2013

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease

scientific article

Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer

scientific article published on 16 September 2021

Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity

scientific article published on 25 April 2016

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

scientific article published on May 2015

Tumour-derived exosomes: Tiny envelopes for big stories.

scientific article published on 29 April 2015

Understanding tumor heterogeneity as functional compartments - superorganisms revisited ⬇️

scientific article published on May 27, 2011

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1.

scientific article

[Cooperation between a somatic mutation and a genetic susceptibility variant in Ewing sarcoma].

scientific article published in April 2016

mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism

scientific article published in 2024

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