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List of works by Ewa Michalak

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

scientific article

Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death.

scientific article published on August 2010

BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.

scientific article published in July 2006

BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.

scientific article published on 23 August 2005

Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic in mice.

scientific article published on 21 August 2013

Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids

scientific article published on 06 August 2018

Developmental stage‐specific contribution of LGR5+ cells to basal and luminal epithelial lineages in the postnatal mammary gland ⬇️

scientific article published on November 1, 2012

Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?

scientific article

ER stress triggers apoptosis by activating BH3-only protein Bim

scientific article (publication date: 29 June 2007)

Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.

scientific article

Maximal killing of lymphoma cells by DNA damage-inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim

scientific article

Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite

scientific article

Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool.

scientific article published in September 2013

Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction

scientific article

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells

scientific article published on 08 January 2014

Recurrent ventricular fibrillation during a febrile illness as the first manifestation of Brugada syndrome--a case report

scientific article published in September 2004

Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.

scientific article published on 22 June 2015

Studying Therapy Response and Resistance in Mouse Models for BRCA1-Deficient Breast Cancer ⬇️

scientific article published on February 18, 2011

Subversion of the Bcl-2 life/death switch in cancer development and therapy.

scientific article published in January 2005

The clinical course and risk in patients with pseudo-Mahaim fibers

scientific article published on 01 January 2008

The roles of DNA, RNA and histone methylation in ageing and cancer

scientific article published on 03 July 2019

Transforming growth factor-β directly induces p53-up-regulated modulator of apoptosis (PUMA) during the rapid induction of apoptosis in myc-driven B-cell lymphomas.

scientific article published on 14 December 2012

Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.

scientific article

Using the GEMM-ESC strategy to study gene function in mouse models.

scientific article published on 15 October 2015

[Ablation of atypical, fast atrio-ventricular nodal tachycardia in a pregnant woman--a case report]

scientific article published on 01 February 2006

[Arrhythmias originating from coronary sinus with multi-level conduction block as a cause of tachyarrhythmic cardiomyopathy reversed by successful RF ablation]

scientific article published on 01 December 2007

p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.

scientific article published on 9 May 2013

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