List of works by Ingo K Mellinghoff

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

scientific article

Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma

scientific article

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

scientific article (publication date: 11 December 2007)

Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

scientific article published on 04 February 2019

Challenges to curing primary brain tumours

scientific article published on 01 August 2019

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

scientific article

Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer

scientific article published on 14 September 2009

EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer

scientific article

Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo

scientific article published on February 2015

IDH mutation impairs histone demethylation and results in a block to cell differentiation

scientific article (publication date: 15 February 2012)

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma.

scientific article published on 15 June 2017

Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma

scientific article

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

article

PHASE II TRIAL OF THE PHOSPHATIDYINOSITOL-3 KINASE (PI3K) INHIBITOR BUPARLISIB (BKM120) IN RECURRENT GLIOBLASTOMA CONDUCTED BY THE IVY FOUNDATION EARLY PHASE CLINICAL TRIALS CONSORTIUM.

scientific article published in July 2014

Phase 1b trial of an ibrutinib-based combination therapy in recurrent/refractory CNS lymphoma

scientific article published on 19 December 2018

Relationship between survival and edema in malignant gliomas: role of vascular endothelial growth factor and neuronal pentraxin 2.

scientific article published in May 2007

Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'

scientific article published on 01 August 2019

Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study

scientific article

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

scientific article published on 29 November 2009

T1-Weighted Dynamic Contrast-Enhanced MRI as a Noninvasive Biomarker of Epidermal Growth Factor Receptor vIII Status

scientific article

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

scientific journal article

Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid

scientific article published on 23 January 2019

Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma

scientific article published on 01 March 2022

Paulina is supported by:

About Paulina

Help