List of works by Keith P. Klugman

220D-F2 from Rubus ulmifolius kills Streptococcus pneumoniae planktonic cells and pneumococcal biofilms

scientific article

2617. Increased Nasopharyngeal Pneumococcal Density During Asymptomatic Respiratory Virus Infection Is Associated with Subsequent Development of Acute Respiratory Illness

3-monthly azithromycin administration for trachoma

scientific article published in August 2009

A Mechanism of Unidirectional Transformation, Leading to Antibiotic Resistance, Occurs within Nasopharyngeal Pneumococcal Biofilm Consortia.

scientific article

A disease model descriptive of progression between chronic obstructive pulmonary disease exacerbations and community-acquired pneumonia: roles for underlying lung disease and the pharmacokinetics/pharmacodynamics of the antibiotic

scientific article

A framework for global surveillance of antibiotic resistance

scientific article published on 08 April 2011

A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa

scientific article published in March 2020

A new paradigm in pneumococcal conjugate vaccination: moving from individual to herd protection.

scientific article published on 24 April 2017

A role for Streptococcus pneumoniae in virus-associated pneumonia

scientific article published on 11 July 2004

A tale of 2 pneumococcal vaccines

scientific article published on 13 February 2014

A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection

scientific article

Access to effective antimicrobials: a worldwide challenge

scientific article

Acquisition of Streptococcus pneumoniae in pneumococcal conjugate vaccine-naïve South African children and their mothers

scientific article published in May 2013

Acquisition of chloramphenicol resistance by the linearization and integration of the entire staphylococcal plasmid pC194 into the chromosome of Streptococcus pneumoniae

scientific article

Acute Respiratory Infections

Altered PBP 2A and its role in the development of penicillin, cefotaxime, and ceftriaxone resistance in a clinical isolate of Streptococcus pneumoniae.

scientific article

Amino acid mutations essential to production of an altered PBP 2X conferring high-level beta-lactam resistance in a clinical isolate of Streptococcus pneumoniae

scientific article

An association between decreasing incidence of invasive non-typhoidal salmonellosis and increased use of antiretroviral therapy, Gauteng Province, South Africa, 2003-2013.

scientific article

An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome

scientific article

An unusual pneumococcal sequence type is the predominant cause of serotype 3 invasive disease in South Africa

scientific article

Analysis of penicillin-binding protein genes of clinical isolates of Streptococcus pneumoniae with reduced susceptibility to amoxicillin.

scientific article

Antibiotic non-susceptibility among Streptococcus pneumoniae and Haemophilus influenzae isolates identified in African cohorts: a meta-analysis of three decades of published studies

scientific article published on 23 September 2013

Antibiotic prescribing practices for common childhood illnesses in South Africa.

scientific article

Antibiotic prophylaxis-Preventing severe infections and saving lives in poor countries with very high mortality risk.

scientific article published on 26 June 2018

Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children.

scientific article published in June 2003

Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases

scientific article

Antibiotic-resistant pneumococcal pneumonia.

scientific article

Antibiotics for paediatric community-acquired pneumonia in resource-constrained settings

scientific article published on 17 September 2020

Antihypertensives suppress the emergence of fluoroquinolone-resistant mutants in pneumococci: an in vitro study

scientific article published on 14 March 2013

Antimicrobial resistance in developing countries. Part I: recent trends and current status

scientific article published in August 2005

Antimicrobial resistance in developing countries. Part II: strategies for containment

scientific article published in September 2005

Antimicrobial susceptibility and molecular epidemiology of Streptococcus pneumoniae isolated from Shanghai, China.

scientific article published on 23 August 2008

Antimicrobial susceptibility of pneumococcal isolates causing bacteraemic pneumococcal pneumonia: analysis using current breakpoints and fluoroquinolone pharmacodynamics

scientific article published on 7 April 2010

Apnea and its possible relationship to immunization in ex-premature infants

article by Peter A. Cooper et al published June 2008 in Vaccine

Assessing the Evidence for Maternal Pertussis Immunization: A Report From the Bill & Melinda Gates Foundation Symposium on Pertussis Infant Disease Burden in Low- and Lower-Middle-Income Countries.

scientific article

Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data

scientific article

Association of Laboratory Methods, Colonization Density, and Age With Detection of Streptococcus pneumoniae in the Nasopharynx

scientific article published on 01 December 2019

Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis

scientific article published on September 2010

Association of serotypes of Streptococcus pneumoniae with disease severity and outcome in adults: an international study.

scientific article published on 31 May 2007

Bacteraemic pneumococcal pneumonia: Impact of HIV on clinical presentation and outcome

article

Bacterial Density, Serotype Distribution and Antibiotic Resistance of Pneumococcal Strains from the Nasopharynx of Peruvian Children Before and After Pneumococcal Conjugate Vaccine 7.

scientific article published on April 2016

Bacterial aetiology of non-resolving otitis media in South African children

scientific article published on March 2003

Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism

scientific article published on 08 October 2020

Bacterial pathogens and death during the 1918 influenza pandemic

scientific article published in December 2009

Benefits to mother and child of influenza vaccination during pregnancy

scientific article published on January 2012

COVID-19 pneumonia and the appropriate use of antibiotics

scientific article published on 10 November 2020

Capsule homology does not increase the frequency of transformation of linked penicillin binding proteins PBP 1a and PBP 2x in Streptococcus pneumoniae

scientific article published on April 2005

Changing Diagnostic Paradigms for Microbiology: Report on an American Academy of Microbiology Colloquium held in Washington, DC, from 17 to 18 October 2016

Childhood pneumonia in developing countries

scientific article published on 18 June 2013

Chlorhexidine Maternal-Vaginal and Neonate Body Wipes in Sepsis and Vertical Transmission of Pathogenic Bacteria in South Africa: A Randomized, Controlled Trial

article

Chlorhexidine maternal-vaginal and neonate body wipes in sepsis and vertical transmission of pathogenic bacteria in South Africa: a randomised, controlled trial

scientific article

Clinical and Microbiological Features of Salmonella Meningitis in a South African Population, 2003-2013

scientific article

Clinical and microbiological features of invasive nontyphoidal Salmonella associated with HIV-infected patients, Gauteng Province, South Africa

scientific article published on March 2017

Clinical epidemiology of bocavirus, rhinovirus, two polyomaviruses and four coronaviruses in HIV-infected and HIV-uninfected South African children

scientific article published on 03 February 2014

Clinical impact of antibiotic resistance in respiratory tract infections

scientific article published on February 2007

Clonal analysis of Neisseria meningitidis serogroup B strains in South Africa, 2002 to 2006: emergence of new clone ST-4240/6688.

scientific article

Cluster of an erythromycin-resistant variant of the Spanish multiply resistant 23F clone of Streptococcus pneumoniae in South Africa

scientific article published in February 1994

Cohort profile: The study of respiratory pathogens in Andean children

scientific article

Combination Antibiotic Therapy Lowers Mortality among Severely Ill Patients with Pneumococcal Bacteremia

scientific article published on 07 June 2004

Communicating trends in resistance using a drug resistance index

scientific article published on 14 November 2011

Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns

scientific article published on February 2002

Competitive Dominance within Biofilm Consortia Regulates the Relative Distribution of Pneumococcal Nasopharyngeal Density

scientific article published on 2 June 2017

Conserved mutations in the pneumococcal bacteriocin transporter gene, blpA, result in a complex population consisting of producers and cheaters

scientific article

Contribution of Serologic Assays in the Evaluation of Influenza Virus Infection Rates and Vaccine Efficacy in Pregnant Women: Report From Randomized Controlled Trials

scientific article

Contribution of vaccines to our understanding of pneumococcal disease

scientific article

Correction: Expression of Streptococcus pneumoniae Virulence-Related Genes in the Nasopharynx of Healthy Children.

scientific article published on 3 January 2014

Correlation between erythromycin and azithromycin resistance in Streptococcus pneumoniae.

scientific article

Cost-effectiveness of pneumococcal conjugate vaccine: an update after 7 years of use in the United States

scientific article published on 29 August 2009

Defining the estimated core genome of bacterial populations using a Bayesian decision model

scientific article

Defining the potential impact of conjugate bacterial polysaccharide-protein vaccines in reducing the burden of pneumonia in human immunodeficiency virus type 1-infected and -uninfected children

scientific article published in May 2002

Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children

scientific article

Detection of Penicillin Resistance in Streptococcus pneumoniae by a Seminested PCR Strategy

scientific article published in January 2001

Determinants of invasiveness beneath the capsule of the pneumococcus

scientific article published on 5 September 2013

Development and Characterization of a Synthetic DNA, NUversa, to Be Used as a Standard in All Quantitative PCR Reactions for Molecular Pneumococcal Serotyping.

scientific article published on 4 October 2017

Development and characterization of a synthetic DNA, NUversa, to be used as a standard in quantitative polymerase chain reactions for molecular pneumococcal serotyping

scientific article

Development of the Respiratory Index of Severity in Children (RISC) score among young children with respiratory infections in South Africa

scientific article

Differing manifestations of respiratory syncytial virus-associated severe lower respiratory tract infections in human immunodeficiency virus type 1-infected and uninfected children

scientific article published on February 2001

Distribution of factor H binding protein beyond serogroup B: variation among five serogroups of invasive Neisseria meningitidis in South Africa

scientific article published on 7 December 2010

Dose response of CRM197 and tetanus toxoid-conjugated Haemophilus influenzae type b vaccines

scientific article published in December 2004

Drug Resistance

Dynamics of Colonization of Streptococcus pneumoniae Strains in Healthy Peruvian Children.

scientific article published on 17 February 2018

Dynamics of Increasing IFN-γ Exposure on Murine MH-S Cell-Line Alveolar Macrophage Phagocytosis of Streptococcus pneumoniae

scientific article

Dynamics of pneumococcal transmission in vaccine-naive children and their HIV-infected or HIV-uninfected mothers during the first 2 years of life

scientific article published on 3 October 2013

Economic burden of acute lower respiratory tract infection in South African children

scientific article published on May 2012

Editorial: Breathing new life into pneumonia epidemiology

scientific article published on 4 October 2009

Effect of 13-valent pneumococcal conjugate vaccine on admissions to hospital 2 years after its introduction in the USA: a time series analysis

article

Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants

scientific article

Effectiveness of 7-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in HIV-infected and -uninfected children in south africa: a matched case-control study

scientific article

Effectiveness of the 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in South African children: a case-control study

scientific article

Effects of vaccination on invasive pneumococcal disease in South Africa

scientific article published on 11 November 2014

Efficacy of Whole‐Cell Killed Bacterial Vaccines in Preventing Pneumonia and Death during the 1918 Influenza Pandemic ⬇️

scientific article published on October 28, 2010

Efficacy of maternal influenza vaccination against all-cause lower respiratory tract infection hospitalizations in young infants: Results from a randomized controlled trial

scientific article published on 29 May 2017

Eliminating Meningococcal Epidemics From the African Meningitis Belt: The Case for Advanced Prevention and Control Using Next-Generation Meningococcal Conjugate Vaccines

scientific article published on 01 October 2019

Emergence and spread of Streptococcus pneumoniae with erm(B) and mef(A) resistance

scientific article

Emergence of Streptococcus pneumoniae with very-high-level resistance to penicillin

scientific article published on August 2004

Emergence of endemic serogroup W135 meningococcal disease associated with a high mortality rate in South Africa

scientific article published in February 2008

Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in a South African child in a tuberculosis treatment facility

scientific article published in November 2003

Emergence of levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance study

scientific article

Epidemiological differences among pneumococcal serotypes

scientific article

Epidemiology of Group B Streptococcus in developing countries

scientific article published on August 2013

Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003-2013.

scientific article published on February 2016

Epidemiology of invasive bacterial infections in pneumococcal conjugate vaccine-vaccinated and -unvaccinated children under 5 years of age in Soweto, South Africa: a cohort study from a high-HIV burden setting

scientific article published on 03 June 2019

Epidemiology of invasive pneumococcal disease among high-risk adults since the introduction of pneumococcal conjugate vaccine for children

scientific article published on 15 November 2012

Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: South Africa, 2003-2008.

scientific article published on 16 May 2013

Erratum for Geno et al., "Pneumococcal Capsules and Their Types: Past, Present, and Future"

scientific article published on 23 December 2020

Estimated severe pneumococcal disease cases and deaths before and after pneumococcal conjugate vaccine introduction in children younger than 5 years of age in South Africa

scientific article

Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies

scientific article

Evidence for clonal expansion after antibiotic selection pressure: pneumococcal multilocus sequence types before and after mass azithromycin treatments

scientific article published on 6 October 2014

Evidence for soft selective sweeps in the evolution of pneumococcal multidrug resistance and vaccine escape

scientific article

Expression of Streptococcus pneumoniae Virulence-Related Genes in the Nasopharynx of Healthy Children

scientific article

Factors associated with ceftriaxone nonsusceptibility of Streptococcus pneumoniae: analysis of South African national surveillance data, 2003 to 2010.

scientific article

Failures of beta-lactam therapy for invasive pneumococcal disease.

scientific article published in October 2004

Fitness costs of fluoroquinolone resistance in Streptococcus pneumoniae.

scientific article

Five-year cohort study of hospitalization for respiratory syncytial virus associated lower respiratory tract infection in African children

scientific article published on 5 May 2006

Fluoroquinolone resistance among clinical isolates of Streptococcus pneumoniae belonging to international multiresistant clones.

scientific article

Fluoroquinolone-resistant Streptococcus pneumoniae

scientific article published on September 2006

Future challenges in the elimination of bacterial meningitis

scientific article published on May 2012

Gender as a risk factor for both antibiotic resistance and infection with pediatric serogroups/serotypes, in HIV-infected and -uninfected adults with pneumococcal bacteremia.

scientific article

Genetic diversity of penicillin-binding protein 2B and 2X genes from Streptococcus pneumoniae in South Africa

scientific article published on September 1993

Genomic load from sputum samples and nasopharyngeal swabs for diagnosis of pneumococcal pneumonia in HIV-infected adults

scientific article

Genotypic comparison of invasive Neisseria meningitidis serogroup Y isolates from the United States, South Africa, and Israel, isolated from 1999 through 2002. ⬇️

scientific article published on July 2009

Global Distribution of Invasive Serotype 35D Streptococcus pneumoniae Isolates following Introduction of 13-Valent Pneumococcal Conjugate Vaccine. ⬇️

scientific article

Global Funders Consortium for Universal Influenza Vaccine Development

article

Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis

scientific article

Global epidemiology of invasive meningococcal disease

scientific article published on 10 September 2013

Global perspectives on maternal immunisation.

scientific article

Global practices of meningococcal vaccine use and impact on invasive disease

scientific article

Guidelines for empiric antimicrobial prescribing in community-acquired pneumonia

scientific article published on May 2004

HIV Infection and the Epidemiology of Invasive Pneumococcal Disease (IPD) in South African Adults and Older Children Prior to the Introduction of a Pneumococcal Conjugate Vaccine (PCV).

scientific article published on 10 February 2016

HIV and influenza virus infections are associated with increased blood pneumococcal load: a prospective, hospital-based observational study in South Africa, 2009-2011.

scientific article published on 6 August 2013

HIV and pneumococcal disease

scientific article published on February 2007

Haemophilus influenzae type b conjugate vaccine diluted tenfold in diphtheria-tetanus-whole cell pertussis vaccine: a randomized trial

scientific article published on 01 February 2002

Herd immunity after pneumococcal conjugate vaccination

scientific article published on 01 July 2007

Herd protection induced by pneumococcal conjugate vaccine

scientific article published on 28 May 2014

Heterogeneous macrolide resistance and gene conversion in the pneumococcus

scientific article

Hidden epidemic of macrolide-resistant pneumococci

scientific article

High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia

scientific article published on 6 June 2014

High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae

scientific article published on 8 January 2007

Historical changes in pneumococcal serogroup distribution: implications for the era of pneumococcal conjugate vaccines.

scientific article published on 7 August 2002

Human metapneumovirus genetic variability, South Africa

scientific article

Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants

scientific article published on 19 November 2003

Identifying transmission routes of Streptococcus pneumoniae and sources of acquisitions in high transmission communities

scientific article

Immunogenicity after one, two or three doses and impact on the antibody response to coadministered antigens of a nonavalent pneumococcal conjugate vaccine in infants of Soweto, South Africa

scientific article published on 01 November 2002

Immunogenicity and effectiveness of Haemophilus influenzae type b conjugate vaccine in HIV infected and uninfected African children

scientific article published in August 2005

Immunogenicity and safety of different dosing schedules of trivalent inactivated influenza vaccine in pregnant women with HIV: a randomised controlled trial

scientific article published on 03 January 2020

Impact of 13-valent pneumococcal conjugate vaccine (PCV13) in a pandemic similar to the 2009 H1N1 in the United States

scientific article

Impact of conjugate Haemophilus influenzae type b (Hib) vaccine introduction in South Africa.

scientific article published on October 2006

Impact of conjugate pneumococcal vaccines on antibiotic resistance

scientific article published on December 2008

Impact of cotrimoxazole on non-susceptibility to antibiotics in Streptococcus pneumoniae carriage isolates among HIV-infected mineworkers in South Africa

scientific article

Impact of existing vaccines in reducing antibiotic resistance: Primary and secondary effects

article published in the Proceedings of the National Academy of Sciences of the United States of America

Impact of experimental human pneumococcal carriage on nasopharyngeal bacterial densities in healthy adults

scientific article

Impact of haemophilus influenzae type b conjugate vaccine in South Africa and Argentina

scientific article published in September 2004

Impact of pneumococcal conjugate vaccination of infants on pneumonia and influenza hospitalization and mortality in all age groups in the United States

scientific article

Impact of pneumococcal conjugate vaccine on vaccine serotype specific pneumonia

scientific article published on 18 December 2020

Impact of the Hajj on pneumococcal transmission

scientific article published on 12 October 2014

Implications for antimicrobial prescribing of strategies based on bacterial eradication

scientific article

Implications of bacterial resistance for the use of beta-lactam agents in clinical practice.

scientific article

Imputing the Direct and Indirect Effectiveness of Childhood Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease by Surveying Temporal Changes in Nasopharyngeal Pneumococcal Colonization

scientific article published on 6 May 2017

In vitro activity of faropenem against respiratory pathogens

scientific article published in March 2002

In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae

scientific article published on 17 November 2008

In-vitro activity of cefepime against bacterial pathogens from hospitalized patients

scientific article published on 01 July 1993

In-vitro activity of the fluoroquinolone trovafloxacin against penicillin-susceptible and -resistant Streptococcus pneumoniae

scientific article published on 01 November 1995

Increased Nasopharyngeal Density and Concurrent Carriage of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Are Associated with Pneumonia in Febrile Children

scientific article

Increased activity of 16-membered lactone ring macrolides against erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae: characterization of South African isolates

scientific article published on 01 December 1998

Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States

scientific article

Increased incidence of meningococcal disease in HIV-infected individuals associated with higher case-fatality ratios in South Africa

scientific article published in June 2010

Increased prevalence of pediatric pneumococcal serotypes in elderly adults.

scientific article published on 11 July 2005

Increased risk for and mortality from invasive pneumococcal disease in HIV-exposed but uninfected infants aged <1 year in South Africa, 2009-2013.

scientific article published on 2 February 2015

Increased risk of death in human immunodeficiency virus-infected children with pneumococcal meningitis in South Africa, 2003-2005.

scientific article published in December 2011

Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis

scientific article

Increasing prevalence of penicillin-resistant pneumococcal infections in children in southern Israel: implications for future immunization policies.

scientific article published on September 1994

Ineffectiveness of trimethoprim-sulfamethoxazole prophylaxis and the importance of bacterial and viral coinfections in African children with Pneumocystis carinii pneumonia

scientific article published on 7 October 2002

Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization

scientific article

Influence of bacterial interactions on pneumococcal colonization of the nasopharynx

scientific article published on 25 December 2012

Influenza Vaccination of Pregnant Women and Protection of Their Infants

Influenza guideline for South Africa--update 2008.

scientific article published on March 2008

Influenza vaccination of pregnant women and protection of their infants

scientific article

Innovations in pneumonia diagnosis and treatment: a call to action on World Pneumonia Day, 2013

article

Interaction between influenza virus and Streptococcus pneumoniae in severe pneumonia

scientific article

International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact

scientific article published on 16 April 2019

International pneumococcal clones match or exceed the fitness of other strains despite the accumulation of antibiotic resistance

scientific article

International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum beta-lactamase production in nosocomial Infections

scientific article published in January 2004

Interrelationship of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus colonization within and between pneumococcal-vaccine naïve mother-child dyads

scientific article

Interspecies recombination in type II topoisomerase genes is not a major cause of fluoroquinolone resistance in invasive Streptococcus pneumoniae isolates in the United States ⬇️

scientific article

Interspecies recombination occurs frequently in quinolone resistance-determining regions of clinical isolates of Streptococcus pyogenes

scientific article published on 2 September 2008

Introduction: historical perspective and development of amoxicillin/clavulanate

scientific article

Invasive Neisseria meningitidis with decreased susceptibility to fluoroquinolones in South Africa, 2009.

scientific article published on 4 August 2010

Invasive disease caused simultaneously by dual serotypes of Streptococcus pneumoniae

scientific article published on 8 November 2017

Invasive disease due to Haemophilus influenzae serotype b ten years after routine vaccination, South Africa, 2003-2009.

scientific article published on 26 November 2011

Invasive pneumococcal pneumonia and respiratory virus co-infections

scientific article published in February 2012

Leveraging the COVID-19 response to end preventable child deaths from pneumonia

scientific article published on 11 November 2020

Levofloxacin-resistant invasive Streptococcus pneumoniae in the United States: evidence for clonal spread and the impact of conjugate pneumococcal vaccine ⬇️

scientific article published on September 2004

Live attenuated influenza vaccine enhances colonization of Streptococcus pneumoniae and Staphylococcus aureus in mice

scientific article published on 18 February 2014

Live attenuated influenza vaccine, but not pneumococcal conjugate vaccine, protects against increased density and duration of pneumococcal carriage after influenza infection in pneumococcal colonized mice.

scientific article published on 11 July 2013

Live attenuated influenza virus increases pneumococcal translocation and persistence within the middle ear.

scientific article published on 11 December 2014

Long-term antibody levels and booster responses in South African children immunized with nonavalent pneumococcal conjugate vaccine

scientific article published in July 2004

Long-term effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae--and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization--in HIV-Infected and HIV-uninfected childre

scientific article published on 25 October 2007

Long-term immunogenicity and efficacy of a 9-valent conjugate pneumococcal vaccine in human immunodeficient virus infected and non-infected children in the absence of a booster dose of vaccine

scientific article published on 20 September 2006

Longitudinal study on Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonization in HIV-infected and -uninfected infants vaccinated with pneumococcal conjugate vaccine

scientific article published on 21 April 2015

Low prevalence of fluoroquinolone resistant strains and resistance precursor strains in Streptococcus pneumoniae from patients with community-acquired pneumonia despite high fluoroquinolone usage ⬇️

scholarly article by Mathias W. Pletz et al published January 2011 in International Journal of Medical Microbiology

Lower respiratory tract infections associated with influenza A and B viruses in an area with a high prevalence of pediatric human immunodeficiency type 1 infection

scientific article published in April 2002

Marking November 12, 2010 - World Pneumonia Day: where are we, where are vaccines?

scientific article published on 01 November 2010

Maternal influenza immunization and reduced likelihood of prematurity and small for gestational age births: a retrospective cohort study

scientific article

Maternal interventions vigilance harmonization in low- and middle-income countries: Stakeholder meeting report; Amsterdam, May 1-2, 2018.

scientific article

Meningococcal disease in South Africa, 1999-2002.

scientific article published on February 2007

Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data

scientific article

Molecular basis and clonal nature of increasing pneumococcal macrolide resistance in South Africa, 2000-2005.

scientific article published on 12 March 2008

Molecular characterization of emerging non-levofloxacin-susceptible pneumococci isolated from children in South Africa

scientific article published on 04 March 2009

Mortality in penicillin-resistant pneumococcal meningitis

scientific article published in July 2008

Multiplex Urinary Antigen Detection for 13 Streptococcus pneumoniae Serotypes Improves Diagnosis of Pneumococcal Pneumonia in South African HIV-Infected Adults

scientific article

Mutations within the rplD Gene of Linezolid-Nonsusceptible Streptococcus pneumoniae Strains Isolated in the United States

scientific article published on 3 February 2014

Nasopharyngeal Pneumococcal Density Is Associated With Viral Activity but Not With Use of Improved Stoves Among Young Andean Children

scientific article published on 2 August 2017

Nasopharyngeal Pneumococcal Density and Evolution of Acute Respiratory Illnesses in Young Children, Peru, 2009-2011.

scientific article

Nasopharyngeal Pneumococcal Density during Asymptomatic Respiratory Virus Infection and Risk for Subsequent Acute Respiratory Illness

scientific article published on 01 November 2019

Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma

scientific article

Nasopharyngeal carriage of community-acquired, antibiotic-resistant Streptococcus pneumoniae in a Zambian paediatric population

scientific article published on January 1997

Nasopharyngeal carriage of pneumococcal pediatric serotypes: a risk for acute and recurrent otitis media in children and for invasive disease in susceptible adults

scientific article published on 28 April 2005

Neisseria meningitidis intermediately resistant to penicillin and causing invasive disease in South Africa in 2001 to 2005.

scientific article published on 23 July 2008

No impact of penicillin resistance on mortality

scientific article published on 01 July 2006

Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network

scientific article

Novel approaches to the identification of Streptococcus pneumoniae as the cause of community-acquired pneumonia

scientific article published on December 2008

Novel mechanism of resistance to oxazolidinones, macrolides, and chloramphenicol in ribosomal protein L4 of the pneumococcus

scientific article

Novel role for the Streptococcus pneumoniae toxin pneumolysin in the assembly of biofilms

scientific article published on 10 September 2013

One enzyme inactivates two antibiotics

scientific article published in January 2006

Oral antibiotics for the treatment of severe pneumonia in children

scientific article published in September 2004

Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumoniae in the United States, 1996-2003.

scientific article published in October 2011

PERCH in Perspective: What Can It Teach Us About Pneumonia Etiology in Children?

scientific article

Part IV. Human infections and antibiotic resistance

scientific article published on 28 July 2011

Path to impact: A report from the Bill and Melinda Gates Foundation convening on maternal immunization in resource-limited settings; Berlin - January 29-30, 2015.

scientific article published on 24 August 2015

Pathogen replication, host inflammation, and disease in the upper respiratory tract

scientific article published on 14 January 2013

Persistent high burden of invasive pneumococcal disease in South African HIV-infected adults in the era of an antiretroviral treatment program

scientific article (publication date: 2011)

Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989 to 2013.

scientific article published on 9 March 2016

Pneumococcal Capsules and Their Types: Past, Present, and Future

scientific article

Pneumococcal Coinfection with Human Metapneumovirus

scientific article published in 2006

Pneumococcal Conjugate Vaccine Protection against Coronavirus-Associated Pneumonia Hospitalization in Children Living with and without HIV

scientific article published on 08 January 2021

Pneumococcal capsular switching: a historical perspective

scientific article published on 21 November 2012

Pneumococcal colonisation density: a new marker for disease severity in HIV-infected adults with pneumonia

scientific article

Pneumococcal conjugate vaccines: proceedings from an interactive symposium at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy

scientific article published in April 2003

Pneumococcal diseases

scientific article published on 01 January 1998

Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study

scientific article published on 10 June 2019

Pneumococcal pneumonia and influenza: a deadly combination

scientific article

Pneumococcal polysaccharide vaccine efficacy and routine use of conjugate vaccines in infants: there is no need for a vaccine program in older adults at present

scientific article published on 17 August 2012

Pneumococcal vaccination in developing countries.

scientific article

Pneumococcal vaccines and flu preparedness

scientific article published in Science

Pneumonia vaccines for all who need them

scientific article published on 16 November 2009

Polyomaviruses-associated respiratory infections in HIV-infected and HIV-uninfected children

scientific article

Population snapshot of Streptococcus pneumoniae causing invasive disease in South Africa prior to introduction of pneumococcal conjugate vaccines

scientific article

Population snapshot of invasive serogroup B meningococci in South Africa from 2005 to 2008 ⬇️

scientific article

Population versus individual protection by pneumococcal conjugate vaccination

scientific article published on 15 April 2019

Preparing to introduce new maternal immunizations in low- and lower-middle-income countries: A report from the Bill & Melinda Gates Foundation convening "Allies in Maternal and Newborn Care"; May 3-4, 2018

scientific article published on 14 May 2020

Prevalence of first-step mutants among levofloxacin-susceptible invasive isolates of Streptococcus pneumoniae in the United States ⬇️

scientific article

Prevalence of maternal colonisation with group B streptococcus: a systematic review and meta-analysis

scientific article published on 25 May 2016

Prevention of neonatal pneumonia and sepsis via maternal immunisation

scientific article published on 12 November 2014

Public health and economic impact of the 13-valent pneumococcal conjugate vaccine (PCV13) in the United States

scientific article published on 28 September 2010

Public health and economic impact of vaccination with 7-valent pneumococcal vaccine (PCV7) in the context of the annual influenza epidemic and a severe influenza pandemic.

scientific article

Putative novel cps loci in a large global collection of pneumococci

scientific article published on 11 June 2019

Putting flu on the agenda

scholarly article by Colin Russell et al published December 2015 in Vaccine

Quantitative and qualitative anamnestic immune responses to pneumococcal conjugate vaccine in HIV-infected and HIV-uninfected children 5 years after vaccination.

scientific article published in April 2009

Quantitative and qualitative antibody response to pneumococcal conjugate vaccine among African human immunodeficiency virus-infected and uninfected children

scientific article

Quinolone treatment for pediatric bacterial meningitis: a comparative study of trovafloxacin and ceftriaxone with or without vancomycin

scientific article published in January 2002

Quorum-sensing systems LuxS/autoinducer 2 and Com regulate Streptococcus pneumoniae biofilms in a bioreactor with living cultures of human respiratory cells

scientific article published on 12 February 2013

Randomized, placebo-controlled trial on safety and efficacy of inactivated influenza vaccination of pregnant women in preventing illness in their infants

scholarly article by Shabir A. Madhi et al published April 2014 in International Journal of Infectious Diseases

Rationale for revised penicillin susceptibility breakpoints versus Streptococcus pneumoniae: coping with antimicrobial susceptibility in an era of resistance

scientific article published on June 2009

Re-examination of immune response and estimation of anti-Vi IgG protective threshold against typhoid fever-based on the efficacy trial of Vi conjugate in young children

scientific article

Recommendations for treatment of childhood non-severe pneumonia.

scientific article published on March 2009

Reduced effectiveness of Haemophilus influenzae type b conjugate vaccine in children with a high prevalence of human immunodeficiency virus type 1 infection

scientific article published in April 2002

Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae

scientific article published on 11 August 2015

Reply to "no clinical association of live attenuated influenza vaccine with nasal carriage of bacteria or acute otitis media": specific recommendations for future studies

scientific article

Resurgence of the multiresistant pneumococcus in the United States: a commentary

scientific article published on 01 June 2007

Risk factors for invasive pneumococcal disease among children less than 5 years of age in a high HIV prevalence setting, South Africa, 2010 to 2012.

scientific article

Risk factors for multidrug-resistant invasive pneumococcal disease in South Africa, a setting with high HIV prevalence, in the prevaccine era from 2003 to 2008

scientific article

Role of Streptococcus pneumoniae in hospitalization for acute community-acquired pneumonia associated with culture-confirmed Mycobacterium tuberculosis in children: a pneumococcal conjugate vaccine probe study

scientific article published in December 2010

Seasonality of respiratory viruses causing hospitalizations for acute respiratory infections in children in Nha Trang, Vietnam

scientific article published on 14 August 2018

Seasonality, incidence, and repeat human metapneumovirus lower respiratory tract infections in an area with a high prevalence of human immunodeficiency virus type-1 infection

scientific article

Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis

scientific article

Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants

scientific article

Serotype 6C is associated with penicillin-susceptible meningeal infections in human immunodeficiency virus (HIV)-infected adults among invasive pneumococcal isolates previously identified as serotype 6A in South Africa

scientific article published on 23 August 2008

Serotype specific cardiac involvement in pneumococcal pneumonia

scientific article published on 22 September 2020

Severity of illness scoring systems in patients with bacteraemic pneumococcal pneumonia: implications for the intensive care unit care

scholarly article by C. Feldman et al published September 2009 in Clinical Microbiology and Infection

Single report of β-lactam resistance in an invasive Haemophilus influenzae isolate from South Africa mediated by mutations in penicillin-binding protein 3, 2003-2008.

scientific article published on 16 September 2010

Single-plex quantitative assays for the detection and quantification of most pneumococcal serotypes

scientific article published on 23 March 2015

Site-specific mutagenesis analysis of PBP 1A from a penicillin-cephalosporin-resistant pneumococcal isolate

scientific article

Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group

scientific article published on December 2013

Strain Level Streptococcus Colonization Patterns during the First Year of Life

scientific article published on 6 September 2017

Streptococcus pneumoniae Serotypes and Mortality in Adults and Adolescents in South Africa: Analysis of National Surveillance Data, 2003 - 2008.

scientific article

Streptococcus pneumoniae bacteraemia: pharmacodynamic correlations with outcome and macrolide resistance--a controlled study

scientific article published on 22 June 2007

Surveillance for antimicrobial drug resistance in under-resourced countries

scientific article (publication date: March 2014)

Surveillance of resistance in bacteria causing community-acquired respiratory tract infections

scientific article

Surveillance of the impact of pneumococcal conjugate vaccines in developing countries

scientific article published on 26 August 2015

Susceptibility of Bacillus anthracis to eleven antimicrobial agents including novel fluoroquinolones and a ketolide

scientific article

Susceptibility of Yersinia pestis to novel and conventional antimicrobial agents

scientific article published on 15 July 2003

Systemic Shigellosis in South Africa

article

Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation

scientific article

Temporal association of infant immunisation with pneumococcal conjugate vaccine on the ecology of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonisation in a rural South African community

scientific article published on 4 August 2014

Temporal changes in pneumococcal colonization in a rural African community with high HIV prevalence following routine infant pneumococcal immunization

scientific article published on November 2013

The "Achilles heel" of global efforts to combat infectious diseases

scientific article published on 01 May 2006

The LuxS-dependent quorum-sensing system regulates early biofilm formation by Streptococcus pneumoniae strain D39.

scientific article

The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal Carriage in Vaccine Evaluation Studies

scientific article published on 17 November 2015

The Relevance of a Novel Quantitative Assay to Detect up to 40 Major Streptococcus pneumoniae Serotypes Directly in Clinical Nasopharyngeal and Blood Specimens

scientific article

The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition

scientific article

The anticipated severity of a "1918-like" influenza pandemic in contemporary populations: the contribution of antibacterial interventions

scientific article (publication date: 2012)

The battle against emerging antibiotic resistance: should fluoroquinolones be used to treat children?

scientific article published on 20 August 2002

The case for launch of an international DNA-based birth cohort study

scientific article

The emergence of bacterial "hopeful monsters"

scientific article published on 29 July 2014

The future of paediatric pneumococcal conjugate vaccines

scientific article published on 27 March 2017

The future of pneumococcal disease prevention

scientific article

The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1.

scientific article published on 09 January 2017

The impact of HIV on Streptococcus pneumoniae bacteraemia in a South African population

scientific article published on November 1998

The impact of a 9-valent pneumococcal conjugate vaccine on the public health burden of pneumonia in HIV-infected and -uninfected children

scientific article published on 7 April 2005

The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis

article

The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success

scientific article published on 16 November 2012

The relationship between pneumococcal serotypes and antibiotic resistance

scientific article published on 11 February 2012

The remaining challenge of pneumonia: the leading killer of children

scientific article published on 01 January 2011

The role of bacterial vaccines in the prevention of influenza mortality

scientific article published on 01 December 2018

The role of clonality in the global spread of fluoroquinolone-resistant bacteria

scientific article

The role of influenza and parainfluenza infections in nasopharyngeal pneumococcal acquisition among young children

scientific article published on 12 March 2014

The role of influenza in the severity and transmission of respiratory bacterial disease

scientific article

The significance of serotype replacement for pneumococcal disease and antibiotic resistance

scientific article published on 01 January 2009

Time for a third-generation pneumococcal conjugate vaccine

scientific article published on 20 July 2020

Time from illness onset to death, 1918 influenza and pneumococcal pneumonia

scientific article published in February 2009

Timing of serotype 1 pneumococcal disease suggests the need for evaluation of a booster dose

scientific article published on 9 March 2011

Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease

scientific article published on 9 January 2012

Trivalent influenza vaccination randomized control trial of pregnant women and adverse fetal outcomes

scientific article published on 19 July 2019

Two cases of serotypeable and non-serotypeable variants of Streptococcus pneumoniae detected simultaneously during invasive disease

scientific article

Typhoid Fever in South Africa in an Endemic HIV Setting

scientific article

Undernutrition and pneumonia mortality.

scientific article published on December 2015

Understanding pneumococcal serotype 1 biology through population genomic analysis

scientific article published on 8 November 2016

Use of 2 pneumococcal common protein real-time polymerase chain reaction assays in healthy children colonized with Streptococcus pneumoniae.

scientific article

Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia

scientific article published on 8 December 2011

Use of near-real-time medical claims data to generate timely vaccine coverage estimates in the US: the dynamics of PCV13 vaccine uptake

scientific article

Use of procalcitonin and C-reactive protein to evaluate vaccine efficacy against pneumonia

scientific article

Usefulness of C-reactive protein to define pneumococcal conjugate vaccine efficacy in the prevention of pneumonia

scientific article

Usefulness of the serial measurement of Vi antibodies

scientific article published on 17 January 2018

Vaccination to reduce antimicrobial resistance

scientific article published on 08 November 2017

Vaccination: a novel approach to reduce antibiotic resistance

scientific article published on 16 August 2004

Vaccines as tools against resistance: the example of pneumococcal conjugate vaccine

scientific article published on April 2004

Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone

scientific article published on 23 June 2014

Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections

scientific article

Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates

scientific article published on 30 April 2020

Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation

scientific article published on 10 July 2020

World Health Organisation definition of "radiologically-confirmed pneumonia" may under-estimate the true public health value of conjugate pneumococcal vaccines

scientific article published on 18 September 2006

World Pneumonia Day 2016: pulse oximetry and oxygen.

scientific article published on 10 November 2016

Younger ages at risk of Covid-19 mortality in communities of color

scientific article published on 26 June 2020

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