Search filters

List of works by Vojo Deretic

13[C]-urea breath test as a novel point-of-care biomarker for tuberculosis treatment and diagnosis

scientific article

4th International Symposium on Autophagy: exploiting the frontiers of autophagy research

scientific article published on 4 March 2007

A comprehensive glossary of autophagy-related molecules and processes

scientific article published on 16 May 2010

A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

scientific article

A master conductor for aggregate clearance by autophagy

scientific article published on May 2010

A set of cassettes and improved vectors for genetic and biochemical characterization of Pseudomonas genes

scientific article published in January 1987

A tale of two lipids: Mycobacterium tuberculosis phagosome maturation arrest.

scientific article published on February 2004

AMPK is activated during lysosomal damage via a galectin-ubiquitin signal transduction system

scientific article published on 28 June 2020

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System

scientific article published on 28 January 2020

ATG9A protects the plasma membrane from programmed and incidental permeabilization

scientific article published on 12 July 2021

AlgR, a response regulator controlling mucoidy in Pseudomonas aeruginosa, binds to the FUS sites of the algD promoter located unusually far upstream from the mRNA start site

scientific article

AlgR-binding sites within the algD promoter make up a set of inverted repeats separated by a large intervening segment of DNA ⬇️

scientific article published on October 1, 1992

Ambroxol and Ciprofloxacin Show Activity Against SARS-CoV2 in Vero E6 Cells at Clinically-Relevant Concentrations

scientific article published on 11 August 2020

Ambroxol induces autophagy and potentiates Rifampin antimycobacterial activity

scientific article published on 27 August 2018

An essential two-component signal transduction system in Mycobacterium tuberculosis

scientific article

Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress response

scientific journal article

Analysis of the oxyR-ahpC region in isoniazid-resistant and -susceptible Mycobacterium tuberculosis complex organisms recovered from diseased humans and animals in diverse localities

scientific article published on March 1997

Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7.

scientific article

Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens

scientific article published on 12 August 2020

Autophagic proteolysis of long-lived proteins in nonliver cells.

scientific article

Autophagosome Formation: Cutting the Gordian Knot at the ER

scientific article published on 01 April 2018

Autophagosome and phagosome

scientific article published on January 2008

Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens

scientific article

Autophagosomes and lipid droplets: no longer just chewing the fat.

scientific article published on 10 July 2015

Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosomes... wait, I'm confused

scientific article published on 17 March 2014

Autophagy and HIV

scientific article

Autophagy and Mycobacterium tuberculosis

scholarly article published 28 August 2006

Autophagy and inflammation: A special review issue

scientific article

Autophagy and p62/sequestosome 1 generate neo-antimicrobial peptides (cryptides) from cytosolic proteins ⬇️

scientific article published on March 1, 2011

Autophagy and pattern recognition receptors in innate immunity

scientific article

Autophagy as an immune defense mechanism

scientific article published on 19 June 2006

Autophagy as an immune effector against tuberculosis

scientific article published on 18 June 2013

Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors ⬇️

scientific article published on November 24, 2011

Autophagy balances inflammation in innate immunity

scientific article published on 22 November 2017

Autophagy gives a nod and a wink to the inflammasome and Paneth cells in Crohn's disease

scientific article published on November 2008

Autophagy in immune defense against Mycobacterium tuberculosis

scientific article

Autophagy in immunity against mycobacterium tuberculosis: a model system to dissect immunological roles of autophagy

scientific article

Autophagy in immunity and cell‐autonomous defense against intracellular microbes ⬇️

scientific article published on March 1, 2011

Autophagy in infection

scientific article (publication date: April 2010)

Autophagy in infection, inflammation, and immunity

scientific article (publication date: October 2013)

Autophagy in innate and adaptive immunity.

scientific article

Autophagy in leukocytes and other cells: mechanisms, subsystem organization, selectivity, and links to innate immunity

scientific article

Autophagy in tuberculosis

scientific article

Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation

scientific article published on 05 June 2012

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

scientific article (publication date: 17 December 2004)

Autophagy of intracellular microbes and mitochondria: two sides of the same coin? ⬇️

scientific article published on June 23, 2010

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

scientific article published on July 2009

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

scientific article

Autophagy's secret life: secretion instead of degradation

scientific article published on 12 December 2017

Autophagy, Immunity, and Microbial Adaptations

scientific article

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year

scientific article published on 15 July 2019

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

scientific article published on 01 January 2018

Autophagy, an immunologic magic bullet: Mycobacterium tuberculosis phagosome maturation block and how to bypass it.

scientific article published on October 2008

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

scientific article (publication date: 8 November 2011)

Autophagy: An Emerging Immunological Paradigm ⬇️

scientific article published on July 1, 2012

Ay, There’s the Rab: Organelle Maturation by Rab Conversion

scientific article published on 01 October 2005

Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells

scientific article published on 01 April 2020

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

scientific article

Biochemical Characterization and Posttranslational Modification of Algu, a Regulator of Stress Response in Pseudomonas aeruginosa

article

Broad-host-range plasmid and M13 bacteriophage-derived vectors for promoter analysis in Escherichia coli and Pseudomonas aeruginosa

article

CFTR and pseudomonas infections in cystic fibrosis

scientific article

Cell biology of mycobacterium tuberculosis phagosome.

scientific article published in January 2004

Cellubrevin alterations and Mycobacterium tuberculosis phagosome maturation arrest

scientific article published on February 2002

Cellular and molecular mechanism for secretory autophagy

scientific article published on 3 April 2017

Characterization of the genes coding for the putative sigma factor AlgU and its regulators MucA, MucB, MucC, and MucD in Azotobacter vinelandii and evaluation of their roles in alginate biosynthesis

scientific article published on April 1996

Chloroquine normalizes aberrant transforming growth factor beta activity in cystic fibrosis bronchial epithelial cells.

scientific article published on August 2006

Control of AlgU, a member of the sigma E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis

scientific journal article

Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy

scientific article

Control of autophagy initiation by phosphoinositide 3-phosphatase jumpy

Conversion of Pseudomonas aeruginosa to mucoidy in cystic fibrosis: environmental stress and regulation of bacterial virulence by alternative sigma factors

scientific article published on May 1994

Conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients

scientific article

Conversion to mucoidy in Pseudomonas aeruginosa.

scientific article published on October 1993

Correction: TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation.

scientific article published in March 2017

Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy

scientific article published on 08 December 2016

Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties.

scientific article

Differentiation of Pseudomonas aeruginosa into the alginate-producing form: inactivation of mucB causes conversion to mucoidy

scientific article

Dual regulation of mucoidy in Pseudomonas aeruginosa and sigma factor antagonism

scientific article published in April 2000

Effects of cytokines on mycobacterial phagosome maturation ⬇️

scientific article published on April 1, 1998

Elements of signal transduction in Mycobacterium tuberculosis: in vitro phosphorylation and in vivo expression of the response regulator MtrA

scientific journal article

Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A-induced cytotoxicity

scientific article

Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade

scientific article

Endosomal membrane traffic: convergence point targeted by Mycobacterium tuberculosis and HIV.

scientific article published in November 2004

Enhancement of lung levels of antibiotics by ambroxol and bromhexine

scientific article published on 07 February 2019

Functional equivalence of Escherichia coli sigma E and Pseudomonas aeruginosa AlgU: E. coli rpoE restores mucoidy and reduces sensitivity to reactive oxygen intermediates in algU mutants of P. aeruginosa

scientific article published on June 1995

Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal

scientific article published on 05 December 2019

Galectins Control mTOR in Response to Endomembrane Damage

scientific article published in April 2018

Galectins and TRIMs directly interact and orchestrate autophagic response to endomembrane damage

scientific article published on 3 April 2017

Galectins control MTOR and AMPK in response to lysosomal damage to induce autophagy

scientific article published on 05 November 2018

Gene cluster controlling conversion to alginate-overproducing phenotype in Pseudomonas aeruginosa: functional analysis in a heterologous host and role in the instability of mucoidy

scientific article

Gene expression in mycobacteria: transcriptional fusions based on xylE and analysis of the promoter region of the response regulator mtrA from Mycobacterium tuberculosis

scientific article published on 01 September 1994

Global genomic analysis of AlgU (sigma(E))-dependent promoters (sigmulon) in Pseudomonas aeruginosa and implications for inflammatory processes in cystic fibrosis

scientific article

Green fluorescent protein as a marker for gene expression and cell biology of mycobacterial interactions with macrophages

scientific article published on September 1995

Green fluorescent protein. A tool for gene expression and cell biology in mycobacteria

scientific article published on January 1998

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

Higher order Rab programming in phagolysosome biogenesis.

scientific article

Host dependenet inactivation by IS2 of induced E.coli penicillin amidase gene cloned on multicopy plasmids

article

How cells clean house.

scientific article published in May 2008

Human IRGM induces autophagy to eliminate intracellular mycobacteria

scientific article (publication date: 8 September 2006)

Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

scientific article

Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses

scientific article

Hyperacidification in cystic fibrosis: links with lung disease and new prospects for treatment

scientific article

Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells

scientific article (publication date: 19 April 2002)

IRGM Governs the Core Autophagy Machinery to Conduct Antimicrobial Defense

scientific article (publication date: May 2015)

Identification of the algZ gene upstream of the response regulator algR and its participation in control of alginate production in Pseudomonas aeruginosa

scientific article published on January 1997

Immunocytochemical analysis of AlgP (Hp1), a histonelike element participating in control of mucoidy in Pseudomonas aeruginosa ⬇️

scientific article published on February 1, 1992

Immunologic manifestations of autophagy

scientific article

In vitro interactions of the histone-like protein IHF with the algD promoter, a critical site for control of mucoidy in Pseudomonas aeruginosa

scientific article

In vitro phagosome-endosome fusion

scientific article published in January 2008

In vitro phosphorylation of AlgR, a regulator of mucoidy in Pseudomonas aeruginosa, by a histidine protein kinase and effects of small phospho-donor molecules

scientific article published on 01 October 1992

Induction of p38 mitogen-activated protein kinase reduces early endosome autoantigen 1 (EEA1) recruitment to phagosomal membranes.

scientific article published on 8 September 2003

Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria

scientific article published on 24 March 2003

Innate immunity, the constant gardener of antimicrobial defense ⬇️

scientific article published on July 20, 2013

Interactions of OxyR with the promoter region of the oxyR and ahpC genes from Mycobacterium leprae and Mycobacterium tuberculosis

scientific article published on April 1997

Links between autophagy, innate immunity, inflammation and Crohn's disease

scientific article published on 24 September 2009

Loss of oxyR in Mycobacterium tuberculosis

scientific article published on September 1997

Lysosomal positioning coordinates cellular nutrient responses.

scientific article published on 13 March 2011

MERIT, a cellular system coordinating lysosomal repair, removal and replacement

scientific article published on 10 June 2020

Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens

scientific article published on 03 August 2020

Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs

scientific article published on 18 October 2019

Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB

scientific article published on 19 October 2020

Mapping of Mycobacterium tuberculosis katG promoters and their differential expression in infected macrophages.

scientific article published in July 2001

Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.

scientific article

Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy.

scientific article published on 27 August 2015

Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients

scientific article published on September 1993

Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes

scientific article (publication date: December 2007)

Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis

scientific article

Mechanisms of action of isoniazid

scientific article (publication date: December 2006)

Membrane-to-cytosol redistribution of ECF sigma factor AlgU and conversion to mucoidy in Pseudomonas aeruginosa isolates from cystic fibrosis patients

scientific article published in April 2000

Microarray Analysis of Global Gene Expression in Mucoid Pseudomonas aeruginosa.

scientific article

Microarray analysis and functional characterization of the nitrosative stress response in nonmucoid and mucoid Pseudomonas aeruginosa.

scientific article

Microarray analysis of global gene expression in mucoid Pseudomonas aeruginosa

scientific article

Microarray analysis reveals induction of lipoprotein genes in mucoid Pseudomonas aeruginosa: implications for inflammation in cystic fibrosis.

scientific article published on September 2004

Molecular and physiological effects of mycobacterial oxyR inactivation

scientific article published on April 2006

Molecular basis for defective glycosylation and Pseudomonas pathogenesis in cystic fibrosis lung ⬇️

scientific article published on November 20, 2001

Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid

scientific article published on November 1996

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Monitoring autophagy during Mycobacterium tuberculosis infection

scientific article

Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection ⬇️

scientific article published on September 1, 1997

Mucoid Pseudomonas aeruginosa in cystic fibrosis: mutations in the muc loci affect transcription of the algR and algD genes in response to environmental stimuli

scientific article published on February 1990

Multiple promoters and induction by heat shock of the gene encoding the alternative sigma factor AlgU (sigma E) which controls mucoidy in cystic fibrosis isolates of Pseudomonas aeruginosa

scientific article published on October 1995

Multiple regulatory and effector roles of autophagy in immunity.

scientific article published on February 2009

Mycobacteria inhibit nitric oxide synthase recruitment to phagosomes during macrophage infection

scientific article published on May 2004

Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG

article

Mycobacterial phagosome maturation, rab proteins, and intracellular trafficking.

scientific article published on December 1997

Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest.

scientific article

Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and autophagy as a host defence mechanism

scientific article

Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazid

scientific article

Mycobacterium tuberculosis phagosome maturation arrest: mycobacterial phosphatidylinositol analog phosphatidylinositol mannoside stimulates early endosomal fusion

scientific article published on 14 November 2003

Mycobacterium tuberculosis phagosome maturation arrest: selective targeting of PI3P-dependent membrane trafficking.

scientific article

Mycobacterium tuberculosis prevents inflammasome activation

scientific article published on April 2008

Mycobacterium tuberculosis reprograms waves of phosphatidylinositol 3-phosphate on phagosomal organelles

scientific article

Mycobacterium tuberculosissignal transduction system required for persistent infections ⬇️

scientific article published on October 23, 2001

Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis

scientific article

Nitric oxide generated from isoniazid activation by KatG: source of nitric oxide and activity against Mycobacterium tuberculosis

scientific article

Nitrosative stress inhibits production of the virulence factor alginate in mucoid Pseudomonas aeruginosa

article

Nonclassical pathway of Pseudomonas aeruginosa DNA-induced interleukin-8 secretion in cystic fibrosis airway epithelial cells

scientific article published on May 2006

Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons

scientific article published on 24 March 2020

Oxidative Stress Response and Characterization of theoxyR-ahpCandfurA-katGLoci inMycobacterium marinum ⬇️

scientific article published on September 1, 1998

Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis

scientific article

Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.

scientific article published on 27 October 2015

Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis

scientific article

Phosphoinositides in phagolysosome and autophagosome biogenesis

scientific article published on January 2007

Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation

scientific article published on 28 February 2019

Precision autophagy directed by receptor regulators - emerging examples within the TRIM family

scientific article published on 15 February 2016

Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity ⬇️

scientific article published on 01 November 1997

Pseudomonas aeruginosa infection in cystic fibrosis: nucleotide sequence and transcriptional regulation of the algD gene

scientific journal article

Pseudomonas aeruginosa, mucoidy and the chronic infection phenotype in cystic fibrosis

scientific article published on September 1995

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

scientific article

Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest

scientific article

Reactive nitrogen and oxygen intermediates and bacterial defenses: unusual adaptations in Mycobacterium tuberculosis

scientific article

Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis

scientific journal article

Regulators of membrane trafficking and Mycobacterium tuberculosis phagosome maturation block

scientific article

Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy

scientific article published on 10 April 2013

Relief from Zmp1-mediated arrest of phagosome maturation is associated with facilitated presentation and enhanced immunogenicity of mycobacterial antigens.

scientific article

Requirements for nitric oxide generation from isoniazid activation in vitro and inhibition of mycobacterial respiration in vivo

scientific article

Role of autophagy in IL-1β export and release from cells

scientific article published on 23 March 2018

Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest

scientific article

Secretory autophagy

scientific article

Secretory versus degradative autophagy: unconventional secretion of inflammatory mediators

scientific article published on 22 February 2013

Strange bedfellows expose ancient secrets of autophagy in immunity

scientific article published on April 2009

Sustained activation of autophagy suppresses adipocyte maturation via a lipolysis-dependent mechanism

scientific article published on 18 December 2019

T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosis

scholarly article by James Harris et al published October 2007 in Immunity

T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis.

scientific article

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

scientific article (publication date: August 2012)

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition

scientific article

TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction.

scientific article published on January 2014

TRIM-directed selective autophagy regulates immune activation

scientific article

TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity

scientific article

TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation

scientific article published on 25 August 2016

TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1

scientific article published on 02 December 2019

TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis

scientific article published on 28 September 2016

Targeted pulmonary delivery of inducers of host macrophage autophagy as a potential host-directed chemotherapy of tuberculosis

scientific article published on 29 January 2016

Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages.

scientific article published on 17 October 2008

The Mycobacterium tuberculosis phagosome.

scientific article

The Pseudomonas aeruginosa homologs of hemC and hemD are linked to the gene encoding the regulator of mucoidy AlgR.

scientific article published in January 1994

The algD promoter: regulation of alginate production by Pseudomonas aeruginosa in cystic fibrosis

scientific article published on January 1993

The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid ⬇️

scientific article published on November 1, 1996

The inhibition of phagolysosomal biogenesis is fundamental to tuberculosis

scholarly article by Esteban A. Roberts et al published June 2006 in Drug discovery today. Disease mechanisms

The role of PI3P phosphatases in the regulation of autophagy

scientific article

Thematic issue on how autophagosomes find their targets ⬇️

scientific article published on March 1, 2011

Therapeutic targeting of autophagy in neurodegenerative and infectious diseases

scientific article

Toll-like receptors control autophagy.

scientific article

Toll-like receptors in control of immunological autophagy.

scientific article published on 15 May 2009

Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade

scientific article

Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA

scientific journal article

Unveiling the roles of autophagy in innate and adaptive immunity

scientific article published on October 2007

Paulina is supported by:

About Paulina

Help