Search filters

List of works by Azim Surani

220-plex microRNA expression profile of a single cell

scientific article

A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons

scientific article published on 09 March 2020

A human p57(KIP2) transgene is not activated by passage through the maternal mouse germline

scientific article published in November 1999

A molecular programme for the specification of germ cell fate in mice

scientific article published in July 2002

A new route to rejuvenation

scientific article published in Nature

A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC.

scientific article

A position-dependent transgene reveals patterns of gene expression in the developing brain

scientific article published in September 1990

A sensitive multiplex assay for piRNA expression

scientific article

A silencer element identified in Drosophila is required for imprinting of H19 reporter transgenes in mice.

scientific article published on August 1999

A sporadic super state

scientific article published in Nature

A tripartite transcription factor network regulates primordial germ cell specification in mice

scientific article

Agouti germ line gets acquisitive

scientific article published on 01 November 1999

An imprinting element from the mouse H19 locus functions as a silencer in Drosophila.

scientific article published in June 1997

An intronic DNA sequence within the mouse Neuronatin gene exhibits biochemical characteristics of an ICR and acts as a transcriptional activator in Drosophila

scientific article published on 28 August 2008

Analysis of Esg1 expression in pluripotent cells and the germline reveals similarities with Oct4 and Sox2 and differences between human pluripotent cell lines

scientific article published on 15 September 2005

Analysis of imprinted murine Peg3 locus in transgenic mice

scientific article

Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice

scientific article

Beyond DNA: Programming and Inheritance of Parental Methylomes

scientific article published on May 9, 2013

Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells

scientific article

Blimp1 expression predicts embryonic stem cell development in vitro

scientific article

Blimp1 is a critical determinant of the germ cell lineage in mice

scientific article

Cdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7.

scientific article

Cellular Reprogramming in Pursuit of Immortality

scientific article published on December 7, 2012

Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development

scientific article published on 9 November 2015

Chromatin dynamics during epigenetic reprogramming in the mouse germ line

scientific article

Co-expression of theHGF/SF andc-met genes during early mouse embryogenesis precedes reciprocal expression in adjacent tissues during organogenesis

article

Coadaptation in mother and infant regulated by a paternally expressed imprinted gene.

scientific article

Combinatorial control of cell fate and reprogramming in the mammalian germline

scientific article published on 12 July 2012

Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region.

scientific article published in November 1994

Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development

scientific journal article

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass

scientific article

Correction to ‘Primoridal germ cell specification: a context-dependent cellular differentiation event’.

scientific article published in December 2014

DNA (De)Methylation: The Passive Route to Naïvety?

scientific article published on 17 August 2016

Deterministic and stochastic allele specific gene expression in single mouse blastomeres

scientific article

Development and applications of single-cell transcriptome analysis

scientific article

Development. Programming the X chromosome

scientific article published in January 2004

Developmental Competence for Primordial Germ Cell Fate

scientific article published on 18 February 2016

Differentiation and gene regulation Programming, reprogramming and regeneration

article

Differentiation of 2-cell and 8-cell mouse embryos arrested by cytoskeletal inhibitors

scientific article published on 01 February 1980

Dissecting ensemble networks in ES cell populations reveals micro-heterogeneity underlying pluripotency

Distribution of androgenetic cells in fetal mouse chimeras

scientific article

Dppa2 and Dppa4 are closely linked SAP motif genes restricted to pluripotent cells and the germ line

scientific article published on 21 September 2006

Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states

scientific article published on October 2008

Dynamic heterogeneity and DNA methylation in embryonic stem cells

scientific article

Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state.

scientific article

Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells

scientific article

Epiblast stem cell-based system reveals reprogramming synergy of germline factors

scientific journal article

Epigenesis versus preformation during mammalian development. Introduction

scientific article

Epigenetic Reprogramming of Mouse Germ Cells toward Totipotency

scientific article published on December 7, 2010

Epigenetic Reprogramming of Somatic Nuclei via Cell Fusion

Epigenetic control of transgene expression and imprinting by genotype-specific modifiers

scientific article published on 01 June 1990

Epigenetic regulation of trophoblast development

article

Epigenetic reprogramming in mouse primordial germ cells

scientific article published on 01 September 2002

Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells

scientific article published on October 2009

Epigenomics

Epigenotype switching of imprintable loci in embryonic germ cells.

scientific article published on February 1998

Essential role for Argonaute2 protein in mouse oogenesis

scientific article published on 10 August 2009

Establishment of porcine and human expanded potential stem cells

scientific article published on 03 June 2019

Experimental embryological analysis of genetic imprinting in mouse development

scientific article published on January 1994

Foreword

G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst.

scientific article

Generation of primordial germ cells from pluripotent stem cells

scientific article published on 15 August 2009

Generation of single cell microRNA expression profile

Generation of stella-GFP transgenic mice: a novel tool to study germ cell development

scientific article published in February 2006

Genetic and epigenetic regulators of pluripotency

scientific article published on February 2007

Genetic and functional analysis of neuronatin in mice with maternal or paternal duplication of distal Chr 2.

scientific article published in October 1997

Genetics: immaculate misconception

scientific article

Genomic Reprogramming

article

Genomic Reprogramming

Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap

scientific article published on 3 August 2005

Genomic imprinting and the differential roles of parental genomes in brain development

scientific article published in March 1996

Genomic imprinting determines methylation of parental alleles in transgenic mice

scientific article

Genomic imprinting: control of gene expression by epigenetic inheritance

scientific article published on June 1994

Genomic imprinting: developmental significance and molecular mechanism

scientific article published on August 1, 1991

Genomic structure and parent-of-origin-specific methylation of Peg1.

scientific article published on October 1997

Germ cell specification in mice

scientific article published on April 2007

Germ cells: the eternal link between generations

scientific article published on 9 May 2007

Germ line, stem cells, and epigenetic reprogramming

scientific article

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine

scientific article

H19 acts as a trans regulator of the imprinted gene network controlling growth in mice

scientific journal article

Heterogeneity in imprinted methylation patterns of pluripotent embryonic germ cells derived from pre-migratory mouse germ cells

scientific article published on 17 November 2007

Histone methylation defines epigenetic asymmetry in the mouse zygote

scientific article

Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency

scientific article published on 17 October 2012

Impressions of imprints

scientific article published on 01 December 1994

Imprinted expression of neuronatin from modified BAC transgenes reveals regulation by distinct and distant enhancers

scientific article published in August 2001

Imprinted genes and regulation of gene expression by epigenetic inheritance.

scientific article

Imprinting and X chromosome counting mechanisms determine Xist expression in early mouse development

article

Imprinting and the Initiation of Gene Silencing in the Germ Line

scientific article published on May 1, 1998

Imprinting and the epigenetic asymmetry between parental genomes

scientific article

Increased body fat in mice with a targeted mutation of the paternally expressed imprinted gene Peg3.

scientific article

Influence of extracellular Ca2+ and Mg2+ ions on the second meiotic division of mouse oocytes: Relevance to obtaining haploid and diploid parthenogenetic embryos

scientific article published on 01 August 1977

Influence of sex chromosome constitution on the genomic imprinting of germ cells

scholarly article

Investigating transcriptional states at single-cell-resolution

scientific article published on 17 October 2012

Lineage segregation, pluripotency and X-chromosome inactivation in the pig pre-gastrulation embryo

Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesis

scientific article

Loss of Xist imprinting in diploid parthenogenetic preimplantation embryos

scientific article

Manipulation of the repertoire of digestive enzymes secreted into the gastrointestinal tract of transgenic mice

scientific article

Manipulations of genetic constitution by nuclear transplantation

scientific article published in January 1993

Mapping of the Fas-associated factor 1 gene, Faf1, to mouse chromosome 4C6 by FISH.

scientific article published in March 1997

Membrane-bound steel factor maintains a high local concentration for mouse primordial germ cell motility, and defines the region of their migration

scientific article (publication date: 2011)

Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate

scientific article

MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

scientific article

MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo

scientific article

Microdissection of the mouse egg

scientific article published on 01 June 1983

Molecular and morphological differentiation of the mouse blastocyst after manipulations of compaction with cytochalasin D

scientific article published on 01 October 1981

NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers

scientific article

Naive pluripotency is associated with global DNA hypomethylation

scientific article published on 17 February 2013

Neuroantibodies: ectopic expression of a recombinant anti-substance P antibody in the central nervous system of transgenic mice.

scientific article published in August 1995

Nonparametric Bayesian inference of transcriptional branching and recombination identifies regulators of early human germ cell development

article

Normal germ line establishment in mice carrying a deletion of the Ifitm/Fragilis gene family cluster

scientific article published on 27 May 2008

Nuclear reprogramming by human embryonic stem cells

scientific article

Nuclear reprogramming—alchemy or analysis?

scientific article published on 01 May 2002

Nuclear transplantation in the mouse: heritable differences between parental genomes after activation of the embryonic genome

scientific article published in April 1986

Obituary: Anne McLaren (1927-2007)

scientific article (publication date: 16 August 2007)

Ocat, a paternally expressed gene closely linked and transcribed in the opposite direction to Peg3.

scientific article

On the origin of the human germline

scientific article published on 23 July 2018

Organization and parent-of-origin-specific methylation of imprinted Peg3 gene on mouse proximal chromosome 7.

scientific article published in February 2000

PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos

scientific article

Parallel mechanisms of epigenetic reprogramming in the germline

scientific article published on 03 March 2012

Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein.

scientific article published in February 1996

Perceiving signals, building networks, reprogramming germ cell fate

scientific article published on January 2013

Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila

scientific article published on 15 May 2003

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

scientific journal article

Primordial germ cell specification: a context-dependent cellular differentiation event [corrected].

scientific article

Primordial germ-cell development and epigenetic reprogramming in mammals

scientific article published on January 2013

Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency

scientific article published on December 2010

Proliferation and differentiation of androgenetic cells in fetal mouse chimeras

scientific article

Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline

scientific article

Provision of the immunoglobulin heavy chain enhancer downstream of a test gene is sufficient to confer lymphoid-specific expression in transgenic mice

scientific article published in April 1987

Proximal visceral endoderm and extraembryonic ectoderm regulate the formation of primordial germ cell precursors

scientific article

Publisher Correction: Tracing the transitions from pluripotency to germ cell fate with CRISPR screening

scientific article published in Nature Communications

RNA-Seq analysis to capture the transcriptome landscape of a single cell

scientific article

Rebuilding pluripotency from primordial germ cells

scientific article published on 04 June 2013

Reprogramming of genome function through epigenetic inheritance

scientific article published on November 1, 2001

Reprogramming primordial germ cells (PGC) to embryonic germ (EG) cells

scientific article published on April 2008

Reprogramming primordial germ cells into pluripotent stem cells

scientific article published on 27 October 2008

Resetting the epigenome beyond pluripotency in the germline

scientific article published on June 2009

Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse

scientific article published in February 2003

SOX17 is a critical specifier of human primordial germ cell fate

scientific article

Self-renewing epiblast stem cells exhibit continual delineation of germ cells with epigenetic reprogramming in vitro

scientific article published on 30 September 2009

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

scientific article published on 01 August 1990

Spatial distribution of blastomeres is dependent on cell division order and interactions in mouse morulae

scientific article published on 01 April 1984

Specification of germ cell fate in mice

scientific article

Staged profiling of sperm development in sync

article

Steel factor controls primordial germ cell survival and motility from the time of their specification in the allantois, and provides a continuous niche throughout their migration

scientific article published on 11 March 2009

Stella is a maternal effect gene required for normal early development in mice

scientific article

Stella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition.

scientific article

Stem cells: How to make eggs and sperm

article

Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: biallelic expression and lack of interaction with the H19 enhancers

scientific article published in October 1997

Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotency

scientific article published on 17 December 2013

Synthesis and role of cell surface glycoproteins in preimplantation mouse development

article

Targeted DamID reveals differential binding of mammalian pluripotency factors

scientific article published on 17 October 2018

Targeted chromosome elimination from ES-somatic hybrid cells

scientific article published on 5 November 2006

The 3′ portion of the mouse H19 Imprinting-Control Region is required for proper tissue-specific expression of the Igf2 gene

article

The Role of Exogenous Fibroblast Growth Factor-2 on the Reprogramming of Primordial Germ Cells into Pluripotent Stem Cells

scientific article published on 01 June 2006

The Splotch mutation interferes with muscle development in the limbs

article

The continuing quest to comprehend genomic imprinting

scientific article published on 01 January 2006

The fragilis interferon-inducible gene family of transmembrane proteins is associated with germ cell specification in mice

scientific article

The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells

scientific article

The polycomb-group gene Ezh2 is required for early mouse development

scientific article (publication date: July 2001)

The transcriptional and signalling networks of pluripotency

scientific article published on May 2011

The unfolding body plan of primate embryos in culture

scientific article published on 01 February 2020

Tissue specific loss of proliferative capacity of parthenogenetic cells in fetal mouse chimeras

scientific article

Tracing the Transitions from Pluripotency to Germ Cell Fate with CRISPR Screening

Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA-Seq analysis

scientific article

Tracing the transitions from pluripotency to germ cell fate with CRISPR screening

scientific article published in Nature Communications

Untangling the mysteries of maternal inheritance with polycomb

scientific article

Unusual cell specific expression of a major human cytomegalovirus immediate early gene promoter-lacZ hybrid gene in transgenic mouse embryos

scientific article

X chromosome activity in mouse XX primordial germ cells

scientific article

Xist expression and macroH2A1.2 localisation in mouse primordial and pluripotent embryonic germ cells

scientific article

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure

scientific article published on 30 January 2017

iPS cells: mapping the policy issues

scientific article published on December 2009

mRNA-Seq whole-transcriptome analysis of a single cell

scientific article (publication date: May 2009)