List of works - Giuseppe Astarita

2-arachidonoylglycerol signaling in forebrain regulates systemic energy metabolism

scientific article published on March 2012

A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation.

scientific article published on 15 March 2016

A Novel Approach for Processing LC – Ion Mobility – MS Metabolomics Data.

scientific article published in May 2014

A Serum Small Molecule Biosignature of Radiation Exposure from Total Body Irradiated Patients.

scientific article

A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization.

scientific article

A neuroscientist's guide to lipidomics.

scientific article published on October 2007

A novel lipidomic strategy reveals plasma phospholipid signatures associated with respiratory disease severity in cystic fibrosis patients.

scientific article

A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice

scientific article

Adequate Levothyroxine Doses for the Treatment of Hypothyroidism Newly Discovered During Pregnancy ⬇️

scientific article published on September 20, 2013

An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease.

scientific article

An emerging role for metabolomics in nutrition science.

scientific article

An endocannabinoid signaling system modulates anxiety-like behavior in male Syrian hamsters.

scientific article published on 11 June 2008

Applications of ion-mobility mass spectrometry for lipid analysis.

scientific article published on 17 April 2015

Body weight increase and quality of semen: a controversial association ⬇️

scientific article published on April 3, 2013

Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice

scientific article published on 01 May 2020

CMIP is a negative regulator of T cell signaling

scientific article published on 08 August 2019

Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs.

scientific article published on January 2010

Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients

scientific article published on 22 July 2020

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

scientific article (publication date: May 2009)

Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice

scientific article published on 11 August 2015

Deficiency of Lipoprotein Lipase in Neurons Modifies the Regulation of Energy Balance and Leads to Obesity ⬇️

scientific article published on January 5, 2011

Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease.

scientific article

Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry

scientific article published on 20 December 2006

Diacylglycerol Lipase-α and -β Control Neurite Outgrowth in Neuro-2a Cells through Distinct Molecular Mechanisms ⬇️

scientific article published on April 14, 2011

Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain.

scientific article

Discovery of Lipid Alterations in Biological Samples using UPLC, Ion Mobility Mass Spectrometry and TransOmics

Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain

scientific article

Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease.

scientific article

Endocannabinoid signal in the gut controls dietary fat intake.

scientific article

Fat-induced satiety factor oleoylethanolamide enhances memory consolidation.

scholarly article

Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine

scientific article published on 22 November 2006

Gangliosides in Podocyte Biology and Disease

scientific article published on 17 December 2020

High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II

scientific article published on 30 July 2020

High-Throughput Microfludic Applications

Histone Deacetylase SIRT1 Controls Proliferation, Circadian Rhythm, and Lipid Metabolism during Liver Regeneration in Mice

scientific article published on 15 September 2016

Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain.

scientific article published on 23 October 2007

Investigating the Potential of Ion Mobility-Mass Spectrometry for Microalgae Biomass Characterization

scientific article published on 24 June 2019

Ion mobility derived collision cross sections to support metabolomics applications.

scientific article published on 28 March 2014

Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification

scientific article published on 29 December 2014

Lipidomic analysis of biological samples by liquid chromatography coupled to mass spectrometry.

scientific article published in January 2009

Lipidomic analysis of endocannabinoid metabolism in biological samples.

scientific article published on 14 January 2009

Lipidomics: An Evolving Discipline in Molecular Sciences.

scientific article

Metabolomics and lipidomics using traveling-wave ion mobility mass spectrometry.

scientific article

Multidimensional analytical approach based on UHPLC-UV-ion mobility-MS for the screening of natural pigments

scientific article published on 13 February 2015

Pharmacological characterization of hydrolysis-resistant analogs of oleoylethanolamide with potent anorexiant properties.

scientific article

Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1

scientific article published on 22 January 2013

Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients.

scientific article

Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels.

scientific article

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.

scientific article

Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

scientific article

Serum lipidomic analysis from mixed neutron/X-ray radiation fields reveals a hyperlipidemic and pro-inflammatory phenotype

scientific article published on 14 March 2019

Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine.

scientific article

Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids

scientific article

Targeted lipidomics as a tool to investigate endocannabinoid function.

scientific article published on January 2009

Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome.

scientific article

The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease.

scientific article published on 6 April 2011

The lipid messenger OEA links dietary fat intake to satiety.

scientific article published on October 2008

The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.

scientific article

Traveling Wave Ion Mobility Mass Spectrometry: Metabolomics Applications

scientific article published on 01 January 2019

URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.

scientific article

Unbiased Lipidomics and Metabolomics of Human Brain Samples.

scientific article published in January 2018

Unbiased Metabolomic Investigation of Alzheimer's Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism.

scientific article published on 30 December 2015

Untargeted Metabolomics Reveals Predominant Alterations in Lipid Metabolism Following Light Exposure in Broccoli Sprouts.

scientific article published on 15 June 2015

List of works by Giuseppe Astarita

2-arachidonoylglycerol signaling in forebrain regulates systemic energy metabolism

A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation.

A Novel Approach for Processing LC – Ion Mobility – MS Metabolomics Data.

A Serum Small Molecule Biosignature of Radiation Exposure from Total Body Irradiated Patients.

A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization.

A neuroscientist's guide to lipidomics.

A novel lipidomic strategy reveals plasma phospholipid signatures associated with respiratory disease severity in cystic fibrosis patients.

A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice

Adequate Levothyroxine Doses for the Treatment of Hypothyroidism Newly Discovered During Pregnancy ⬇️

An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease.

An emerging role for metabolomics in nutrition science.

An endocannabinoid signaling system modulates anxiety-like behavior in male Syrian hamsters.

Applications of ion-mobility mass spectrometry for lipid analysis.

Body weight increase and quality of semen: a controversial association ⬇️

Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice

CMIP is a negative regulator of T cell signaling

Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs.

Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice

Deficiency of Lipoprotein Lipase in Neurons Modifies the Regulation of Energy Balance and Leads to Obesity ⬇️

Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease.

Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry

Diacylglycerol Lipase-α and -β Control Neurite Outgrowth in Neuro-2a Cells through Distinct Molecular Mechanisms ⬇️

Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain.

Discovery of Lipid Alterations in Biological Samples using UPLC, Ion Mobility Mass Spectrometry and TransOmics

Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain

Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease.

Endocannabinoid signal in the gut controls dietary fat intake.

Fat-induced satiety factor oleoylethanolamide enhances memory consolidation.

Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine

Gangliosides in Podocyte Biology and Disease

High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II

High-Throughput Microfludic Applications

Histone Deacetylase SIRT1 Controls Proliferation, Circadian Rhythm, and Lipid Metabolism during Liver Regeneration in Mice

Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain.

Investigating the Potential of Ion Mobility-Mass Spectrometry for Microalgae Biomass Characterization

Ion mobility derived collision cross sections to support metabolomics applications.

Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification

Lipidomic analysis of biological samples by liquid chromatography coupled to mass spectrometry.

Lipidomic analysis of endocannabinoid metabolism in biological samples.

Lipidomics: An Evolving Discipline in Molecular Sciences.

Metabolomics and lipidomics using traveling-wave ion mobility mass spectrometry.

Multidimensional analytical approach based on UHPLC-UV-ion mobility-MS for the screening of natural pigments

Pharmacological characterization of hydrolysis-resistant analogs of oleoylethanolamide with potent anorexiant properties.

Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1

Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients.

Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels.

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.

Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

Serum lipidomic analysis from mixed neutron/X-ray radiation fields reveals a hyperlipidemic and pro-inflammatory phenotype

Sympathetic activity controls fat-induced oleoylethanolamide signaling in small intestine.

Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids

Targeted lipidomics as a tool to investigate endocannabinoid function.

Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome.

The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease.

The lipid messenger OEA links dietary fat intake to satiety.

The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide.

Traveling Wave Ion Mobility Mass Spectrometry: Metabolomics Applications

URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.

Unbiased Lipidomics and Metabolomics of Human Brain Samples.

Unbiased Metabolomic Investigation of Alzheimer's Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism.

Untargeted Metabolomics Reveals Predominant Alterations in Lipid Metabolism Following Light Exposure in Broccoli Sprouts.