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List of works by Lydia W T Cheung

Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer.

scientific article

Cancer-associated missense mutations enhance the pluripotency reprogramming activity of OCT4 and SOX17

scientific article published on 17 October 2019

CpG/CpNpG motifs in the coding region are preferred sites for mutagenesis in the breast cancer susceptibility genes.

scientific article published on 4 September 2007

Differential role of gonadotropin-releasing hormone on human ovarian epithelial cancer cell invasion.

scientific article

Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha.

scientific article

Ginsenoside-Rg1 induces angiogenesis via non-genomic crosstalk of glucocorticoid receptor and fibroblast growth factor receptor-1 ⬇️

scientific article published on September 20, 2010

Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9.

scientific article published on November 2006

Gonadotropin-releasing hormone: GnRH receptor signaling in extrapituitary tissues.

scientific article

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors

scientific article

Neomorphic mutations create therapeutic challenges in cancer.

scientific article published on 14 November 2016

Oncogenic pathway driven by p85β: upstream signals to activate p110

scientific article published on 13 July 2020

Preclinical evaluation and reverse phase protein Array-based profiling of PI3K and MEK inhibitors in endometrial carcinoma in vitro.

scientific article published on 9 February 2018

Regulation of the PI3K pathway through a p85α monomer-homodimer equilibrium

scientific article published on 29 July 2015

Systematic Functional Annotation of Somatic Mutations in Cancer.

scientific article published in March 2018

Targeting gonadotropin-releasing hormone receptor inhibits the early step of ovarian cancer metastasis by modulating tumor-mesothelial adhesion.

scientific article published on 20 November 2012

Targeting therapeutic liabilities engendered by PIK3R1 mutations for cancer treatment.

scientific article

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer.

scientific article

p85α neomorphic mutants: splitting away from the canonical path.

scientific article published on 27 May 2015

p85β regulates autophagic degradation of AXL to activate oncogenic signaling

scientific article published on 08 May 2020

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