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List of works by Je-Wook Yu

25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome

scientific article published on 25 October 2016

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

scientific article

Advanced glycation end products impair NLRP3 inflammasome-mediated innate immune responses in macrophages

scientific article

Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling

scientific article published on 18 November 2020

Bacterial Secretant from Pseudomonas aeruginosa Dampens Inflammasome Activation in a Quorum Sensing-Dependent Manner.

scientific article published on 27 March 2017

Brefeldin A-sensitive ER-Golgi vesicle trafficking contributes to NLRP3-dependent caspase-1 activation

scientific article published on 28 December 2018

CIIA Is a Novel Regulator of Detachment-Induced Cell Death

scientific article published on August 1, 2010

Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

scientific article

Defective mitochondrial fission augments NLRP3 inflammasome activation

scientific article

Differential cytoprotective effect of copper- and iron-containing chlorophyllins against oxidative stress-mediated cell death

scientific article published on 01 June 2010

Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa

scientific article published on 25 January 2016

Histone deacetylase 6 negatively regulates NLRP3 inflammasome activation.

scientific article published on 12 October 2015

Inflammasome activation by cell volume regulation and inflammation-associated hyponatremia: A vicious cycle.

scientific article published on 18 May 2016

Inhibition of apoptosis signal-regulating kinase 1 by nitric oxide through a thiol redox mechanism.

scientific article published on 9 December 2003

MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration.

scientific article

Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance.

scientific article published on 7 September 2016

Mutations in NALP12 cause hereditary periodic fever syndromes

scientific article

NLRP3 Inflammasome Contributes to Lipopolysaccharide-induced Depressive-Like Behaviors via Indoleamine 2,3-dioxygenase Induction.

scientific article

Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4.

scientific article published on 20 January 2015

Palmitate and minimally-modified low-density lipoprotein cooperatively promote inflammatory responses in macrophages.

scientific article published on 8 March 2018

Prolonged Exposure to Lipopolysaccharide Induces NLRP3-Independent Maturation and Secretion of Interleukin (IL)-1β in Macrophages.

scientific article published on 25 October 2017

Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death

scientific article published on 12 January 2013

Ribotoxic stress through p38 mitogen-activated protein kinase activates in vitro the human pyrin inflammasome.

scientific article published on 11 March 2013

Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation

scientific article

TRADD is critical for resistance to TRAIL-induced cell death through NF-κB activation

scientific article published on May 27, 2011

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

scientific article (publication date: May 2010)

The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity

scientific article published on 18 September 2013

Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model

scientific article published in 2022

Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner

scientific article published on 23 December 2019