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List of works by Thomas A. Rando

A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration

scientific article published on 01 July 2018

A Wnt-TGFβ2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice

scientific article

A sexy spin on nonrandom chromosome segregation.

scientific article published on June 2013

A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis.

scientific article published in January 2008

Activation of an adipogenic program in adult myoblasts with age

scientific article published on 01 March 2002

Adult stem cells and regenerative medicine-a symposium report

scientific article published on 26 October 2019

Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration

scientific article published in Nature Communications

Ageing and rejuvenation of tissue stem cells and their niches

scientific article published in 2022

Ageing: From stem to stern

scientific article published in Nature

Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion.

scientific article published on 30 March 2017

Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock

scientific article

Aging, stem cells and tissue regeneration: lessons from muscle

scientific article

Alive and well? Exploring disease by studying lifespan

scientific article

All's well that ends well: alternative polyadenylation and its implications for stem cell biology

scientific article

Altered caveolin-3 expression disrupts PI(3) kinase signaling leading to death of cultured muscle cells.

scientific article published on 23 May 2006

Alternative polyadenylation mediates microRNA regulation of muscle stem cell function

scientific article

Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function

scientific article published on 01 November 2019

An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy

scientific article

Artificial sweeteners--enhancing glycosylation to treat muscular dystrophies

scientific article

Assessment of disease activity in muscular dystrophies by noninvasive imaging

scientific article published on 24 April 2013

BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration

scientific journal article

Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle

scientific article published on 24 July 2018

Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss

scientific article

Biomarker system for studying muscle, stem cells, and cancer in vivo.

scientific article published on 30 March 2009

Biomechanics show stem cell necessity for effective treatment of volumetric muscle loss using bioengineered constructs

scientific article published on 10 October 2018

Cardiac aging and rejuvenation--a sense of humors?

scientific article published in August 2013

Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging.

scientific article

Collagen VI regulates satellite cell self-renewal and muscle regeneration.

scientific article

Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c

scientific article published on 28 March 2017

Dystrophin gene repair in mdx muscle precursor cells in vitro and in vivo mediated by RNA-DNA chimeric oligonucleotides

scientific article

Emerging models and paradigms for stem cell ageing

scientific article published on May 2011

Enhanced gene repair mediated by methyl-CpG-modified single-stranded oligonucleotides

scientific article published on December 2009

Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration.

scientific article

Epigenetics and aging.

scientific article

Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells.

scientific article

FOXO3 promotes quiescence in adult muscle stem cells during the process of self-renewal

scientific article (publication date: 8 April 2014)

FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.

scientific article published on 25 July 2013

Fleeting factors, turning back time.

scientific article

Focal adhesion kinase is essential for costamerogenesis in cultured skeletal muscle cells

scientific article

Focal adhesion kinase signaling regulates the expression of caveolin 3 and beta1 integrin, genes essential for normal myoblast fusion.

scientific article

Gene delivery to muscle

scientific article published in February 2002

Geroscience: linking aging to chronic disease

scientific article

Get personal with gene therapy for muscular dystrophy

scientific article published in March 2008

Guest editorial: emergent themes from second annual symposium on regenerative rehabilitation, Pittsburgh, Pennsylvania.

scientific article

H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency

scientific article published on 19 November 2015

H3K4me3 breadth is linked to cell identity and transcriptional consistency.

scientific article published on July 2014

HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into GAlert

scientific article published on April 2017

Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches

scientific article

Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity

scientific article

Heterogeneity in the muscle satellite cell population

scientific article published on 19 September 2010

High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny

scientific article

Honey bee Royalactin unlocks conserved pluripotency pathway in mammals

scientific article published in Nature Communications

Impact papers on aging in 2009.

scientific article

Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells

scientific article published on 20 September 2018

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

scientific article (publication date: 10 August 2007)

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

scientific article published on 14 October 2014

Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential.

scientific article published on 25 January 2018

Interaction between epigenetic and metabolism in aging stem cells

scientific article published on 24 January 2017

Intrinsic changes and extrinsic influences of myogenic stem cell function during aging

scientific article published on January 2007

Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis.

scientific article

Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle.

scientific article published in November 2004

Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting

scientific article

Late‐onset distal muscular dystrophy affecting the posterior calves ⬇️

scientific article (publication date: October 2003)

Lineage of origin in rhabdomyosarcoma informs pharmacological response

scientific article

Long-term increase in mVEGF164 in mouse hindlimb muscle mediated by phage phiC31 integrase after nonviral DNA delivery

scientific article published in August 2006

Losartan improves adipose tissue-derived stem cell niche by inhibiting transforming growth factor-β and fibrosis in skeletal muscle injury.

scientific article

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging.

scientific article published on 15 March 2018

Macrophage-released ADAMTS1 promotes muscle stem cell activation

scientific article published on 22 September 2017

Maintenance of muscle stem-cell quiescence by microRNA-489

scientific journal article

Manifestations and mechanisms of stem cell aging.

scientific article

Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle

scientific article published on 01 May 2019

Mimicking the niche: cytokines expand muscle stem cells

scientific article published on 26 June 2015

Models and Studies of Aging: Executive Summary of a Report from the U13 Conference Series

scientific article published on 29 January 2019

Molecular regulation of stem cell quiescence.

scientific article published on June 2013

Monitoring disease activity noninvasively in the model of Duchenne muscular dystrophy

article published in the Proceedings of the National Academy of Sciences of the United States of America

Myf5 expression during fetal myogenesis defines the developmental progenitors of adult satellite cells.

scientific article published on 29 April 2013

NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3'-untranslated region of MyoD and p21WAF1/CIP1 mRNAs.

scientific article

Non-viral gene therapy for Duchenne muscular dystrophy: progress and challenges

scientific article published on 28 July 2006

Notch signaling is necessary to maintain quiescence in adult muscle stem cells

scientific article published on February 2012

Notch-mediated restoration of regenerative potential to aged muscle

scientific article published on 01 November 2003

Numb-deficient satellite cells have regeneration and proliferation defects.

scientific article published on 29 October 2013

Oligonucleotide-mediated gene therapy for muscular dystrophies

scientific article

Oxidative stress and the pathogenesis of muscular dystrophies

scientific article

Preventing oxidative stress: a new role for XBP1.

scientific article

Prognostic value of telomere length: the long and short of it

scientific article published on 01 August 2006

RNA-binding proteins direct myogenic cell fate decisions

scientific article published on 13 June 2022

Recent advances in the pathogenesis and treatment of neuromuscular diseases

scientific article published on 01 October 2012

Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics

scientific article published on 01 April 2018

Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics.

scientific article published in March 2018

Regenerative medicine: Of fish and men.

scientific article published in February 2014

Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors

scientific article

Rehabilitative exercise and spatially patterned nanofibrillar scaffolds enhance vascularization and innervation following volumetric muscle loss

article

Remarkable preservation of undigested muscle tissue within a Late Cretaceous tyrannosaurid coprolite from Alberta, Canada

scientific article

Restoration of dystrophin expression in mdx muscle cells by chimeraplast-mediated exon skipping ⬇️

scientific article published on May 15, 2003

Sequential activation of individual PKC isozymes in integrin-mediated muscle cell spreading: a role for MARCKS in an integrin signaling pathway

scientific article

Smad3 initiates oxidative stress and proteolysis that underlies diaphragm dysfunction during mechanical ventilation.

scientific article

Sprouting a new take on stem cell aging.

scientific article published on 5 October 2012

Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence

scientific article published on 9 October 2017

Stem Cell Quiescence: Dynamism, Restraint, and Cellular Idling

scientific article published on 01 February 2019

Stem cell ageing and non-random chromosome segregation.

scientific article

Stem cell review series: aging of the skeletal muscle stem cell niche.

scientific article

Stem cells and healthy aging

scientific article

Stem cells as vehicles for youthful regeneration of aged tissues.

scientific article

Stem cells in postnatal myogenesis: molecular mechanisms of satellite cell quiescence, activation and replenishment

scientific article

Stem cells, ageing and the quest for immortality.

scientific article published on June 2006

Strand bias in oligonucleotide-mediated dystrophin gene editing

scientific article

Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease.

scientific article published on December 2015

Taf1 regulates Pax3 protein by monoubiquitination in skeletal muscle progenitors

scientific article published on December 2010

Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field

scientific article published on 05 February 2020

Technology insight: therapy for Duchenne muscular dystrophy-an opportunity for personalized medicine?

scientific article published on 12 February 2008

The CHC22 clathrin-GLUT4 transport pathway contributes to skeletal muscle regeneration.

scientific article

The JAK-STAT pathway is critical in ventilator-induced diaphragm dysfunction

scientific article

The adult muscle stem cell comes of age

scientific article published on 01 August 2005

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

scientific article

The immortal strand hypothesis: segregation and reconstruction.

scientific article

The ins and outs of aging and longevity.

scientific article published on January 2013

The modulation of cellular susceptibility to oxidative stress: protective and destructive actions of Cu,Zn-superoxide dismutase

scientific article

The mortal strand hypothesis: non-random chromosome inheritance and the biased segregation of damaged DNA.

scientific article published on 21 May 2013

The place of genetics in ageing research.

scientific article published on 10 July 2012

The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues.

scientific article published on 3 March 2017

The regenerative rehabilitation collection: a forum for an emerging field

scientific article published on 19 October 2018

The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis

scientific article published in September 2002

The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis

scientific article

The regulation of catalase gene expression in mouse muscle cells is dependent on the CCAAT-binding factor NF-Y.

scientific article

Tissue ageing: do insights into molecular mechanisms of ageing lead to new therapeutic strategies?

scientific article published on 25 May 2008

Tissue-specific stem cells: lessons from the skeletal muscle satellite cell

scientific article

Transcriptional Profiling of Quiescent Muscle Stem Cells In Vivo

scientific article published in November 2017

Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

scientific article published in 2020

Translational strategies and challenges in regenerative medicine.

scientific article published in August 2014

Treatment of volumetric muscle loss in mice using nanofibrillar scaffolds enhances vascular organization and integration

scientific article published on 07 May 2019

Turning back time: reversing tissue pathology to enhance stem cell engraftment

scientific article published on 01 September 2008

Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration.

scientific article published on April 2013

UTX in muscle regeneration--the right dose and the right time.

scientific article published on 21 March 2016

[Proteasomal degradation of Pax3 in skeletal muscle progenitors: one ubiquitin does the trick!]

scientific article published on 01 January 2008

mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance

scientific article published in December 2017

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert)

scientific article

mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism.

scientific article published on 29 March 2019

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