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List of works by Kateřina Vávrová

1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria

scientific article published on 02 June 2014

Ammonium carbamates as highly active transdermal permeation enhancers with a dual mechanism of action

scientific article published on 17 November 2010

Amphiphilic transdermal permeation enhancers: structure-activity relationships.

scientific article

Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications.

scientific article published on 7 May 2016

Behavior of 1-Deoxy-, 3-Deoxy- and N-Methyl-Ceramides in Skin Barrier Lipid Models

scientific article published on 02 March 2020

Biodegradable derivatives of tranexamic acid as transdermal permeation enhancers.

scientific article

Ceramide analogue 14S24 ((S)-2-tetracosanoylamino-3-hydroxypropionic acid tetradecyl ester) is effective in skin barrier repair in vitro.

scientific article published in April 2004

Ceramide analogue 14S24 selectively recovers perturbed human skin barrier.

scientific article published on 17 August 2007

Ceramides in the Skin Lipid Membranes: Length Matters

scientific article published on 06 December 2013

Ceramides with a pentadecasphingosine chain and short acyls have strong permeabilization effects on skin and model lipid membranes

scientific article published on 23 November 2015

Chromatographic methods for the separation of biocompatible iron chelators from their synthetic precursors and iron chelates.

scientific article published in December 2004

Comparison of suction blistering and tape stripping for analysis of epidermal genes, proteins and lipids

scientific article

Complex modulation of peptidolytic activity of cathepsin D by sphingolipids

scientific article published on 23 September 2011

Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis

scientific article published on 05 March 2016

Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.

scientific article published on 8 August 2017

Different Phase Behavior and Packing of Ceramides with Long (C16) and Very Long (C24) Acyls in Model Membranes: Infrared Spectroscopy Using Deuterated Lipids

scientific article published on 21 August 2014

Dimethylamino acid esters as biodegradable and reversible transdermal permeation enhancers: effects of linking chain length, chirality and polyfluorination.

scientific article published on 14 November 2008

Dodecyl Amino Glucoside Enhances Transdermal and Topical Drug Delivery via Reversible Interaction with Skin Barrier Lipids.

scientific article published on 9 January 2017

Effect of ceramide acyl chain length on skin permeability and thermotropic phase behavior of model stratum corneum lipid membranes

scientific article published on 15 December 2010

Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes.

scientific article published on 23 February 2017

Effects of Ceramide and Dihydroceramide Stereochemistry at C-3 on the Phase Behavior and Permeability of Skin Lipid Membranes

scientific article

Effects of omega-O-acylceramide structures and concentrations in healthy and diseased skin barrier lipid membrane models

scientific article published on 19 December 2019

Effects of sphingomyelin/ceramide ratio on the permeability and microstructure of model stratum corneum lipid membranes

scientific article published on 11 May 2014

Emerging small-molecule compounds for treatment of atopic dermatitis: a review.

scientific article published on 15 October 2015

Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAP

scientific article published on 14 June 2011

Esters of 6-aminohexanoic acid as skin permeation enhancers: The effect of branching in the alkanol moiety.

scientific article published in July 2005

Esters of terpene alcohols as highly potent, reversible, and low toxic skin penetration enhancers

scientific article published on 10 October 2019

Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

scientific article published on 27 February 2019

Filaggrin deficiency leads to impaired lipid profile and altered acidification pathways in a 3D skin construct

scientific article published on 23 September 2013

Fluorescent Penetration Enhancers Reveal Complex Interactions among the Enhancer, Drug, Solvent, and Skin

scientific article published on 24 January 2019

Galactosyl Pentadecene Reversibly Enhances Transdermal and Topical Drug Delivery.

scientific article published on 29 June 2017

HPLC method for determination of in vitro delivery through and into porcine skin of adefovir (PMEA)

scientific article published on 18 March 2007

HPLC study on stability of pyridoxal isonicotinoyl hydrazone.

scientific article published on 2 August 2005

Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites--the cardioprotectant dexrazoxane as a model case.

scientific article published on 27 November 2010

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

scientific article

Influence of terminal branching on the transdermal permeation-enhancing activity in fatty alcohols and acids

scientific article published on 07 September 2006

Interactions of hyaluronic Acid with the skin and implications for the dermal delivery of biomacromolecules.

scientific article published on 22 April 2015

L-Serine and glycine based ceramide analogues as transdermal permeation enhancers: polar head size and hydrogen bonding

scientific article

LC-MS/MS identification of the principal in vitro and in vivo phase I metabolites of the novel thiosemicarbazone anti-cancer drug, Bp4eT.

scientific article published on 17 February 2012

Long and very long lamellar phases in model stratum corneum lipid membranes

scientific article published on 18 March 2019

Mathematical calculations of iron complex stoichiometry by direct UV-Vis spectrophotometry.

scientific article published on 11 June 2013

New fluorine-containing hydrazones active against MDR-tuberculosis ⬇️

scientific article published on August 5, 2011

Omega-O-Acylceramides in Skin Lipid Membranes: Effects of Concentration, Sphingoid Base, and Model Complexity on Microstructure and Permeability.

scientific article published on 23 November 2016

Permeability Barrier and Microstructure of Skin Lipid Membrane Models of Impaired Glucosylceramide Processing.

scientific article published on 25 July 2017

Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains.

scientific article

Permeation enhancers in transdermal drug delivery: benefits and limitations

scientific article published on 14 January 2020

Phase separation in ceramide[NP] containing lipid model membranes: neutron diffraction and solid-state NMR.

scientific article

Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics.

scientific article

Probing the role of the ceramide acyl chain length and sphingosine unsaturation in model skin barrier lipid mixtures by (2)H solid-state NMR spectroscopy

scientific article

S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents

scientific article published on 21 November 2016

SAMPA: A free software tool for skin and membrane permeation data analysis.

scientific article

Scalable Synthesis of Human Ultralong Chain Ceramides

scientific article published on 19 October 2015

Short-chain ceramides decrease skin barrier properties.

scientific article

Structural Changes in Ceramide Bilayers Rationalize Increased Permeation through Stratum Corneum Models with Shorter Acyl Tails

scientific article

Structure-Activity Relationships of Nitro-Substituted Aroylhydrazone Iron Chelators with Antioxidant and Antiproliferative Activities

scientific article published on 23 May 2018

Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents

scientific article published on 28 February 2017

Structure-activity relationships of novel salicylaldehyde isonicotinoyl hydrazone (SIH) analogs: iron chelation, anti-oxidant and cytotoxic properties.

scientific article

Synthesis and enhancing effect of transkarbam 12 on the transdermal delivery of theophylline, clotrimazole, flobufen, and griseofulvin.

scientific article published on 2 May 2006

Synthesis and structure-activity relationships of skin ceramides.

scientific article published on January 2010

Synthesis and transdermal permeation-enhancing activity of carbonate and carbamate analogs of Transkarbam 12

scientific article published on 30 August 2006

Synthesis and transdermal permeation-enhancing activity of ketone, amide, and alkane analogs of Transkarbam 12.

scientific article published on 11 January 2006

Synthetic ceramide analogues as skin permeation enhancers: structure-activity relationships

scientific article published on 01 December 2003

TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents.

scientific article

The Role of the Trans Double Bond in Skin Barrier Sphingolipids: Permeability and Infrared Spectroscopic Study of Model Ceramide and Dihydroceramide Membranes

scientific article published on 07 May 2014

The chemistry and biology of 6-hydroxyceramide, the youngest member of the human sphingolipid family

scientific article published on 02 July 2014

Transdermal and dermal delivery of adefovir: effects of pH and permeation enhancers.

scientific article

Transkarbams with terminal branching as transdermal permeation enhancers.

scientific article

Ultrastructural and Molecular Analysis of Ribose-Induced Glycated Reconstructed Human Skin ⬇️

scientific article published on 08 November 2018

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