List of works - Joshua C Bis

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

scientific article published on 12 September 2016

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

A novel Alzheimer disease locus located near the gene encoding tau protein.

scientific article

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

scientific article published on 2 September 2012

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Whole-genome sequence–based analysis of high-density lipoprotein cholesterol

scientific article (publication date: August 2013)

Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension

scientific article published on April 2002

Association of genetic variations with nonfatal venous thrombosis in postmenopausal women.

scientific article published on February 2007

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

scientific article

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

scientific article published on 14 August 2014

52 Genetic Loci Influencing Myocardial Mass

scientific article

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

scientific article published on 19 June 2017

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Independent susceptibility markers for atrial fibrillation on chromosome 4q25.

scientific article

Multiple loci are associated with white blood cell phenotypes

scientific article

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

scientific article published on 12 December 2016

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Ischemic stroke is associated with the ABO locus: the EuroCLOT study

scientific article published on January 2013

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

scientific article

Genome-wide association analysis identifies multiple loci related to resting heart rate

scientific article

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

scientific article

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

scientific article

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

scientific article published on 30 January 2014

Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators

scientific article

Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

scientific article published on 7 February 2015

Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium

scientific article

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

scientific article

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts

scientific article published on April 2009

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

scientific article published on 29 May 2018

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

scientific article

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

scientific article published on 23 December 2011

Multi-ethnic genome-wide association study for atrial fibrillation

article

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

scientific article

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

scientific article published on 14 October 2011

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci

scientific article

Cerivastatin, genetic variants, and the risk of rhabdomyolysis

scientific article

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

scientific article

Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis.

scientific article

GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

scientific article

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

scientific article

A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

scientific article published on 05 May 2013

Effect of Alzheimer's disease risk genes on trajectories of cognitive function in the Cardiovascular Health Study

scientific article published on September 2012

Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium

scientific article

Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

scientific article

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Genetic variation associated with circulating monocyte count in the eMERGE Network

scientific article published on 12 January 2013

Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility.

scientific article published on 09 April 2013

List of works by Joshua C Bis

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

A novel Alzheimer disease locus located near the gene encoding tau protein.

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Whole-genome sequence–based analysis of high-density lipoprotein cholesterol

Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension

Association of genetic variations with nonfatal venous thrombosis in postmenopausal women.

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

52 Genetic Loci Influencing Myocardial Mass

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Novel genetic loci associated with hippocampal volume

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

Independent susceptibility markers for atrial fibrillation on chromosome 4q25.

Multiple loci are associated with white blood cell phenotypes

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Ischemic stroke is associated with the ABO locus: the EuroCLOT study

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

Genome-wide association analysis identifies multiple loci related to resting heart rate

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators

Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

Multi-ethnic genome-wide association study for atrial fibrillation

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci

Cerivastatin, genetic variants, and the risk of rhabdomyolysis

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis.

GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

Effect of Alzheimer's disease risk genes on trajectories of cognitive function in the Cardiovascular Health Study

Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium

Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

Genetic variation associated with circulating monocyte count in the eMERGE Network

Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility.