List of works - Michy P. Kelly

A Role for Phosphodiesterase 11A (PDE11A) in the Formation of Social Memories and the Stabilization of Mood.

scientific article published in January 2017

Acquisition of a novel behavior induces higher levels of Arc mRNA than does overtrained performance

scientific article published in January 2002

Chronic Galphas signaling in the striatum increases anxiety-related behaviors independent of developmental effects

scientific article

Chronically increased Gsalpha signaling disrupts associative and spatial learning.

scientific article published on November 2006

Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP.

scientific article

Constitutive activation of the G-protein subunit Galphas within forebrain neurons causes PKA-dependent alterations in fear conditioning and cortical Arc mRNA expression.

scientific article published on 28 January 2008

Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.

scientific article

Differential function of phosphodiesterase families in the brain: gaining insights through the use of genetically modified animals

scientific article

Does phosphodiesterase 11A (PDE11A) hold promise as a future therapeutic target?

scientific article

Identification of new PDE9A isoforms and how their expression and subcellular compartmentalization in the brain change across the life span.

scientific article published on 5 February 2018

Loss of Function of Phosphodiesterase 11A4 Shows that Recent and Remote Long-Term Memories Can Be Uncoupled

scientific article published on 11 July 2019

Mice expressing constitutively active Gsalpha exhibit stimulus encoding deficits similar to those observed in schizophrenia patients.

scientific article

PDE11A negatively regulates lithium responsivity

scientific article published on 20 September 2016

PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain.

scientific article published on 17 August 2016

Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice.

scientific article published on 24 June 2016

Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes.

scientific article

Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease

scientific article published on 29 February 2020

Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity.

scientific article

The distribution of phosphodiesterase 2A in the rat brain.

scientific article published on 19 September 2012

The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.

scientific article

Therapeutic targeting of 3',5'-cyclic nucleotide phosphodiesterases: inhibition and beyond

scientific article published on 06 August 2019

Transcriptional regulation of neurodevelopmental and metabolic pathways by NPAS3.

scientific article published on 28 June 2011

List of works by Michy P. Kelly

A Role for Phosphodiesterase 11A (PDE11A) in the Formation of Social Memories and the Stabilization of Mood.

Acquisition of a novel behavior induces higher levels of Arc mRNA than does overtrained performance

Chronic Galphas signaling in the striatum increases anxiety-related behaviors independent of developmental effects

Chronically increased Gsalpha signaling disrupts associative and spatial learning.

Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP.

Constitutive activation of the G-protein subunit Galphas within forebrain neurons causes PKA-dependent alterations in fear conditioning and cortical Arc mRNA expression.

Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.

Differential function of phosphodiesterase families in the brain: gaining insights through the use of genetically modified animals

Does phosphodiesterase 11A (PDE11A) hold promise as a future therapeutic target?

Identification of new PDE9A isoforms and how their expression and subcellular compartmentalization in the brain change across the life span.

Loss of Function of Phosphodiesterase 11A4 Shows that Recent and Remote Long-Term Memories Can Be Uncoupled

Mice expressing constitutively active Gsalpha exhibit stimulus encoding deficits similar to those observed in schizophrenia patients.

PDE11A negatively regulates lithium responsivity

PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain.

Phosphodiesterase 11A (PDE11A), Enriched in Ventral Hippocampus Neurons, is Required for Consolidation of Social but not Nonsocial Memories in Mice.

Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes.

Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease

Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity.

The distribution of phosphodiesterase 2A in the rat brain.

The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.

Therapeutic targeting of 3',5'-cyclic nucleotide phosphodiesterases: inhibition and beyond

Transcriptional regulation of neurodevelopmental and metabolic pathways by NPAS3.