Search filters

List of works by Lei Zhang

A TALE nuclease architecture for efficient genome editing

scientific article

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease

scientific article published on 01 July 2019

Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells

scientific article published on 2 March 2015

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

scientific article

Diversifying the structure of zinc finger nucleases for high-precision genome editing

scientific article published on 08 March 2019

Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

scientific article

Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer

scientific article

Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases

scientific article published in 2011

Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. ⬇️

scientific article

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

scientific article (publication date: September 2009)

Enhancing gene editing specificity by attenuating DNA cleavage kinetics

scientific article published on 29 July 2019

Functional footprinting of regulatory DNA.

scientific article published on 31 August 2015

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

scientific article

Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy.

scientific article published on June 2006

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

scientific article published on 14 July 2011

Genetic engineering of human pluripotent cells using TALE nucleases

scientific article (publication date: 7 July 2011)

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

scientific article

Improved specificity of TALE-based genome editing using an expanded RVD repertoire

scientific article published on 23 March 2015

Knockout rats generated by embryo microinjection of TALENs.

scientific article

Knockout rats via embryo microinjection of zinc-finger nucleases

scientific article

Mammalian interspecies substitution of immune modulatory alleles by genome editing

scientific article published on 22 February 2016

Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing

scientific article published on 7 January 2016

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

scientific article (publication date: 21 May 2009)

Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells ⬇️

scientific article published on February 6, 2011

Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors

scientific article (publication date: 15 December 2003)

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases

scientific article published on 26 August 2012

Targeted genome editing across species using ZFNs and TALENs

scientific article

Targeted transgene integration in plant cells using designed zinc finger nucleases

scientific article

Paulina is supported by:

About Paulina

Help