List of works - Haiming Dai

1H, 13C and 15N resonance assignments and the secondary structures of human coactosin like protein (hCLP) D123N.

scientific article published in July 2004

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells.

scientific article published on 25 February 2016

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

scientific article

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

scientific article

CXCR4 Chemokine Receptor Signaling Induces Apoptosis in Acute Myeloid Leukemia Cells via Regulation of the Bcl-2 Family Members Bcl-XL, Noxa, and Bak ⬇️

scientific article published on June 24, 2013

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

scientific article

Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate.

scientific article

Characterization of an alternative BAK-binding site for BH3 peptides

scientific article published on 03 July 2020

Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate

scientific article published on 24 April 2020

Combination treatment of RAD001 and BEZ235 exhibits synergistic antitumor activity via down-regulation of p-4E-BP1/Mcl-1 in small cell lung cancer.

scientific article published on 4 July 2017

Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells.

scientific article

Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis.

scientific article published on 07 April 2009

Contribution of Bcl-2 phosphorylation to Bak binding and drug resistance.

scientific article published on 4 October 2013

Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation.

scientific article published on 14 June 2011

DHHC protein family targets different subsets of glioma stem cells in specific niches

scientific article published on 18 January 2019

Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.

scientific article published on 27 March 2015

Enrichment and detection of circulating tumor cells by immunomagnetic beads and flow cytometry

scientific article published on 21 September 2020

Evaluation of the BH3-only protein Puma as a direct Bak activator

scientific article

Fluorine Pseudocontact Shifts Used for Characterizing the Protein-Ligand Interaction Mode in the Limit of NMR Intermediate Exchange.

scientific article

High cell surface death receptor expression determines type I versus type II signaling

scientific article

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

scientific article

MLN4924 induces Noxa upregulation in acute myelogenous leukemia and synergizes with Bcl-2 inhibitors.

scientific article published on 5 June 2015

Matrix Metalloproteinase 11 Is a Potential Therapeutic Target in Lung Adenocarcinoma

scientific article published on 06 April 2019

Matrix Metalloproteinase Expressions Play Important role in Prediction of Ovarian Cancer Outcome

scientific article published on 12 August 2019

Measurement of BH3-only protein tolerance.

scientific article

Mitochondrial apoptosis and BH3 mimetics

scientific article

Noxa/Bcl-2 Protein Interactions Contribute to Bortezomib Resistance in Human Lymphoid Cells ⬇️

scientific article published on March 22, 2011

Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis.

scientific article

Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size

scientific article published on 3 February 2016

Protein kinase Cbeta modulates ligand-induced cell surface death receptor accumulation: a mechanistic basis for enzastaurin-death ligand synergy.

scientific article

Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4

scientific article

Solution structure of calponin homology domain of Human MICAL-1

scientific article published on 17 October 2006

Solution structure of human SUMO-3 C47S and its binding surface for Ubc9

scientific article (publication date: March 2005)

Solution structure of the second SH3 domain of human CMS and a newly identified binding site at the C-terminus of c-Cbl

scientific article

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization

scientific article published on 4 July 2011

List of works by Haiming Dai

1H, 13C and 15N resonance assignments and the secondary structures of human coactosin like protein (hCLP) D123N.

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells.

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

CXCR4 Chemokine Receptor Signaling Induces Apoptosis in Acute Myeloid Leukemia Cells via Regulation of the Bcl-2 Family Members Bcl-XL, Noxa, and Bak ⬇️

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate.

Characterization of an alternative BAK-binding site for BH3 peptides

Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate

Combination treatment of RAD001 and BEZ235 exhibits synergistic antitumor activity via down-regulation of p-4E-BP1/Mcl-1 in small cell lung cancer.

Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells.

Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis.

Contribution of Bcl-2 phosphorylation to Bak binding and drug resistance.

Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation.

DHHC protein family targets different subsets of glioma stem cells in specific niches

Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.

Enrichment and detection of circulating tumor cells by immunomagnetic beads and flow cytometry

Evaluation of the BH3-only protein Puma as a direct Bak activator

Fluorine Pseudocontact Shifts Used for Characterizing the Protein-Ligand Interaction Mode in the Limit of NMR Intermediate Exchange.

High cell surface death receptor expression determines type I versus type II signaling

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

MLN4924 induces Noxa upregulation in acute myelogenous leukemia and synergizes with Bcl-2 inhibitors.

Matrix Metalloproteinase 11 Is a Potential Therapeutic Target in Lung Adenocarcinoma

Matrix Metalloproteinase Expressions Play Important role in Prediction of Ovarian Cancer Outcome

Measurement of BH3-only protein tolerance.

Mitochondrial apoptosis and BH3 mimetics

Noxa/Bcl-2 Protein Interactions Contribute to Bortezomib Resistance in Human Lymphoid Cells ⬇️

Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis.

Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size

Protein kinase Cbeta modulates ligand-induced cell surface death receptor accumulation: a mechanistic basis for enzastaurin-death ligand synergy.

Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4

Solution structure of calponin homology domain of Human MICAL-1

Solution structure of human SUMO-3 C47S and its binding surface for Ubc9

Solution structure of the second SH3 domain of human CMS and a newly identified binding site at the C-terminus of c-Cbl

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization