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List of works by Kyung-Sun Heo

A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis

scientific article

Activation of PKCbeta(II) and PKCtheta is essential for LDL-induced cell proliferation of human aortic smooth muscle cells via Gi-mediated Erk1/2 activation and Egr-1 upregulation.

scientific article published on 22 January 2008

Alleviation of ascorbic acid-induced gastric high acidity by calcium ascorbate in vitro and in vivo

scientific article published on 22 December 2017

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

scientific article

Anti-apoptotic effects of autophagy via ROS regulation in microtubule-targeted and PDGF-stimulated vascular smooth muscle cells.

scientific article published on 25 April 2018

Antioxidative effects of glycoprotein isolated from Solanum nigrum L.

scientific article published on January 2004

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

scientific article published on April 10, 2012

Comparative analysis of three different protocols for cholinergic neuron differentiation in vitro using mesenchymal stem cells from human dental pulp

scientific article published on 10 June 2019

Cucurbitane Triterpenoids from the Fruits of Momordica Charantia Improve Insulin Sensitivity and Glucose Homeostasis in Streptozotocin-Induced Diabetic Mice

scientific article published on 6 February 2018

Cytotoxic effect of glycoprotein isolated from Solanum nigrum L. through the inhibition of hydroxyl radical-induced DNA-binding activities of NF-kappa B in HT-29 cells

scientific article published on 01 May 2004

De-SUMOylation Enzyme of Sentrin/SUMO-Specific Protease 2 Regulates Disturbed Flow–Induced SUMOylation of ERK5 and p53 that Leads to Endothelial Dysfunction and Atherosclerosis

scientific article published on February 4, 2013

Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events

scientific article published on 30 December 2015

Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function

scientific article

Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction.

scientific article published on 10 November 2011

ERK5 activation in macrophages promotes efferocytosis and inhibits atherosclerosis

scientific article published on 28 April 2014

Effects of glycoprotein isolated from Rhus verniciflua stokes on TPA-induced apoptosis and production of cytokines in cultured mouse primary splenocytes.

scientific article published in December 2003

Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein.

scientific article published on 2 May 2019

Glucagon-Like Peptide-1 and its Cardiovascular Effects

scientific article published on October 1, 2012

Glycoprotein isolated from Solanum nigrum L. inhibits the DNA-binding activities of NF-kappaB and AP-1, and increases the production of nitric oxide in TPA-stimulated MCF-7 cells.

scientific article

Glycoprotein isolated from Solanum nigrum L. modulates the apoptotic-related signals in 12-O-tetradecanoylphorbol 13-acetate-stimulated MCF-7 cells.

scientific article

Hepatoprotective effects of an Acer tegmentosum Maxim extract through antioxidant activity and the regulation of autophagy

scientific article published on 25 April 2019

Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents

scientific article

Inhibition of Collagen-Induced Platelet Aggregation by the Secobutanolide Secolincomolide A from Lindera obtusiloba Blume.

scientific article published on 22 August 2017

Inhibition of Proliferation of Vascular Smooth Muscle Cells by Cucurbitanes from Momordica charantia

scientific article published on 16 June 2017

Inhibition of p90RSK is critical to abolish Angiotensin II-induced rat aortic smooth muscle cell proliferation and migration

scientific article published on 18 December 2019

MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation.

scientific article

Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.

scientific article

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

scientific article

Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.

scientific article published on 29 November 2012

Rubiarbonone C inhibits platelet-derived growth factor-induced proliferation and migration of vascular smooth muscle cells through the focal adhesion kinase, MAPK and STAT3 Tyr705 signalling pathways.

scientific article published on 18 August 2017

Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals

scientific article published on 01 February 2019

Shear stress and atherosclerosis

scientific article published on 30 April 2014

Therapeutic effects of ginsenosides on breast cancer growth and metastasis

scientific article published on 24 August 2020

Therapeutic targets for endothelial dysfunction in vascular diseases

scientific article published on 16 August 2019

p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.

scientific article published on 19 January 2012