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List of works by Tomáš Etrych

Ability of polymer-bound P-glycoprotein inhibitor ritonavir to overcome multidrug resistance in various resistant neuroblastoma cell lines

scientific article published on 8 September 2017

Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting ⬇️

scientific article published on March 8, 2011

Biodegradable star HPMA polymer–drug conjugates: Biodegradability, distribution and anti-tumor efficacy ⬇️

scientific article published on June 15, 2011

Biological therapy of hematologic malignancies: toward a chemotherapy-free era.

scientific article published on 6 October 2017

Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity

scientific article published on 2 November 2005

Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice

scientific article

Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate

scientific article published on 17 May 2017

Doxorubicin attached to HPMA copolymer via amide bond modifies the glycosylation pattern of EL4 cells

scientific article published on 24 February 2010

Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release II: impact of release rate on biodistribution

scientific article published on 19 May 2013

Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release: synthesis and characterization of distribution and tumor accumulation in mice by noninvasive multispectral optical imaging

scientific article published on 10 February 2012

Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers

scientific article published on 7 November 2005

Fluorescence optical imaging in anticancer drug delivery

scientific article published on 15 February 2016

HPMA Copolymer-Conjugated Pirarubicin in Multimodal Treatment of a Patient with Stage IV Prostate Cancer and Extensive Lung and Bone Metastases.

scientific article published in February 2016

HPMA Copolymer-Drug Conjugates with Controlled Tumor-Specific Drug Release

scientific article published on 14 August 2017

HPMA copolymer conjugate with pirarubicin: In vitro and ex vivo stability and drug release study

scientific article

HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy

scientific article published on 12 September 2013

HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity

scientific article

Happy Birthday Karel!

scientific article published in January 2018

Hydrolytically degradable polymer micelles for drug delivery: a SAXS/SANS kinetic study

scientific article published on 25 October 2013

Improved Tumor-Specific Drug Accumulation by Polymer Therapeutics with pH-Sensitive Drug Release Overcomes Chemotherapy Resistance

scientific article

Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy

scientific article published on 2 November 2012

Macromolecular HPMA-based nanoparticles with cholesterol for solid-tumor targeting: detailed study of the inner structure of a highly efficient drug delivery system

scientific article published in August 2012

N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation

scientific article published on 7 August 2010

Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes

scientific article published on 27 December 2013

Noninvasive Optical Imaging of Nanomedicine Biodistribution ⬇️

scientific article published on October 24, 2012

Overcoming cellular multidrug resistance using classical nanomedicine formulations

scientific article published on September 2011

Overcoming multidrug resistance in Dox-resistant neuroblastoma cell lines via treatment with HPMA copolymer conjugates containing anthracyclines and P-gp inhibitors.

scientific article

Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate

scientific article published on 12 November 2016

Polyelectrolyte complex formation and stability when mixing polyanions and polycations in salted media: A model study related to the case of body fluids

article

Polymer carriers for anticancer drugs targeted to EGF receptor

scientific article

Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours

scientific article published on 13 March 2014

Polymer-coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction

scientific article published on March 2004

Preclinical evaluation of linear HPMA-doxorubicin conjugates with pH-sensitive drug release: efficacy, safety, and immunomodulating activity in murine model

scientific article

Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin

scientific article published on 21 November 2016

Synthesis and Properties of Star HPMA Copolymer Nanocarriers Synthesised by RAFT Polymerisation Designed for Selective Anticancer Drug Delivery and Imaging

scientific article

Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications

scientific article published on 8 July 2016

The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel

scientific article published on 6 December 2016

Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics

scientific article published on 16 July 2015

Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage

scientific article published on 21 November 2013

[Missile-Type Tumor-Targeting Polymer Drug, P-THP, Seeks Tumors via Three Different Steps Based on the EPR Effect].

scientific article

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