List of works - Michael P. O'Connell

A spoonful of sugar makes the melanoma go: the role of heparan sulfate proteoglycans in melanoma metastasis.

scientific article

Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma

scientific article published on 29 March 2009

Assaying Wnt5A-mediated invasion in melanoma cells.

scientific article

Change is in the air: the hypoxic induction of phenotype switching in melanoma

scientific article

Correction: ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans

scientific article published on 13 March 2017

Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis

scientific article

Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).

scientific article published on March 2008

ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.

scientific article

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

scientific article

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

scientific article published on 17 October 2016

GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects

scientific article published on 15 May 2019

Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells.

scientific article published on 20 August 2009

Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells.

scientific article published on 3 October 2006

Lack of Wnt5A expression in Merkel cell carcinoma.

scientific article published on January 2010

Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility.

scientific article

Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production

scientific article published on 04 April 2019

PD-L1 up-regulation restrains Th17 cell differentiation in STAT3 loss- and STAT1 gain-of-function patients

scientific article published on 14 July 2017

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

scientific article

The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein

scientific article

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

scientific article

Wnt5A activates the calpain-mediated cleavage of filamin A

scientific article

Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells

scientific article

Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation.

scientific article published on December 2008

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

scientific article published on 4 April 2016

List of works by Michael P. O'Connell

A spoonful of sugar makes the melanoma go: the role of heparan sulfate proteoglycans in melanoma metastasis.

Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma

Assaying Wnt5A-mediated invasion in melanoma cells.

Change is in the air: the hypoxic induction of phenotype switching in melanoma

Correction: ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans

Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis

Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).

ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects

Heparan sulfate proteoglycan modulation of Wnt5A signal transduction in metastatic melanoma cells.

Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells.

Lack of Wnt5A expression in Merkel cell carcinoma.

Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility.

Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production

PD-L1 up-regulation restrains Th17 cell differentiation in STAT3 loss- and STAT1 gain-of-function patients

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

Wnt5A activates the calpain-mediated cleavage of filamin A

Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells

Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation.

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance