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List of works by Thomas Kissel

A new synthesis method and degradation of hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymers (hy-PEI-g-PCL-b-mPEG) as potential DNA delivery vectors

scientific article published in July 2009

ABA-triblock copolymers from biodegradable polyester A-blocks and hydrophilic poly(ethylene oxide) B-blocks as a candidate for in situ forming hydrogel delivery systems for proteins

scientific article

Amine-modified hyperbranched polyesters as non-toxic, biodegradable gene delivery systems

scientific article

Amphiphilic and biodegradable hy-PEI-g-PCL-b-PEG copolymers efficiently mediate transgene expression depending on their graft density

scientific article published on 12 May 2011

Amphiphilic biodegradable PEG-PCL-PEI triblock copolymers for FRET-capable in vitro and in vivo delivery of siRNA and quantum dots.

scientific article

Amphiphilic, low molecular weight poly(ethylene imine) derivatives with enhanced stability for efficient pulmonary gene delivery

scientific article published on February 2011

Biodegradable capsules as non-viral vectors for in vitro delivery of PEI/siRNA polyplexes for efficient gene silencing

scientific article published on 14 October 2014

Biodegradable poly(ethylene carbonate) nanoparticles as a promising drug delivery system with "stealth" potential

scientific article published on 5 April 2011

Biodegradable polymeric nanocarriers for pulmonary drug delivery

scholarly article by Erik Rytting et al published June 2008 in Expert Opinion on Drug Delivery

Biodegradable polymers and their potential use in parenteral veterinary drug delivery systems

scientific article published on June 2004

Biophysical and transfection studies of an amine-modified poly(vinyl alcohol) for gene delivery

scientific article published on November 2005

Biophysical characterization of hyper-branched polyethylenimine-graft-polycaprolactone-block-mono-methoxyl-poly(ethylene glycol) copolymers (hy-PEI-PCL-mPEG) for siRNA delivery

scientific article

Bioreducible polymers with cell penetrating and endosome buffering functionality for gene delivery systems

scientific article

Bioreversibly crosslinked polyplexes of PEI and high molecular weight PEG show extended circulation times in vivo

scientific article

Branched polyesters based on poly[vinyl-3-(dialkylamino)alkylcarbamate-co-vinyl acetate-co-vinyl alcohol]-graft-poly(D,L-lactide-co-glycolide): effects of polymer structure on in vitro degradation behaviour

scientific article

Cellular uptake mechanism and knockdown activity of siRNA-loaded biodegradable DEAPA-PVA-g-PLGA nanoparticles

scientific article

Characterization and in vitro degradation of poly(2,3-(1,4-diethyl tartrate)-co-2,3-isopropyliden tartrate).

scientific article published in July 2004

Characterization of a homologous series of D,L-lactic acid oligomers; a mechanistic study on the degradation kinetics in vitro

scientific article

Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery.

scientific article published on 29 October 2011

Chitosan-based formulations for delivery of DNA and siRNA.

scientific article published on 29 September 2009

Coating of poly(p-xylylene) by PLA-PEO-PLA triblock copolymers with excellent polymer-polymer adhesion for stent applications

scientific article

Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice

scientific article published on 9 January 2011

Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport.

scientific article

Computational insights into the interactions between DNA and siRNA with "rigid" and "flexible" triazine dendrimers

scientific article published on March 2010

Controlled pulmonary drug and gene delivery using polymeric nano-carriers

scientific article published on 13 December 2011

Controlled release of gentamicin from calcium phosphate-poly(lactic acid-co-glycolic acid) composite bone cement

scientific article published on 18 April 2006

Copolymers of ethylene imine and N-(2-hydroxyethyl)-ethylene imine as tools to study effects of polymer structure on physicochemical and biological properties of DNA complexes

scientific article

Core-cross-linked polymeric micelles as paclitaxel carriers

scientific article

Crosslinked nanocarriers based upon poly(ethylene imine) for systemic plasmid delivery: in vitro characterization and in vivo studies in mice

scientific article published on 20 January 2007

DNA nano-carriers from biodegradable cationic branched polyesters are formed by a modified solvent displacement method

scientific article published on 24 February 2006

Delivery of messenger RNA using poly(ethylene imine)–poly(ethylene glycol)-copolymer blends for polyplex formation: Biophysical characterization and in vitro transfection properties ⬇️

scientific article published on September 18, 2010

Deposition of nanoparticles in the arterial vessel by porous balloon catheters: localization by confocal laser scanning microscopy and transmission electron microscopy.

scientific article

Design and biophysical characterization of bioresponsive degradable poly(dimethylaminoethyl methacrylate) based polymers for in vitro DNA transfection

scientific article

Design of amine-modified graft polyesters for effective gene delivery using DNA-loaded nanoparticles

scientific article

Development of a biodegradable nanoparticle platform for sildenafil: formulation optimization by factorial design analysis combined with application of charge-modified branched polyesters

scientific article published on 10 September 2011

Development of a delivery system for the continuous endogenous release of an anti-idiotypic antibody against ovarian carcinoma

scientific article published on June 2005

Distribution and quantification of polyethylenimine oligodeoxynucleotide complexes in human skin after iontophoretic delivery using confocal scanning laser microscopy.

scientific article

Do cell culture conditions influence the carrier-mediated transport of peptides in Caco-2 cell monolayers?

scientific article

Drug eluting stents based on Poly(ethylene carbonate): optimization of the stent coating process

scientific article

Effect of PEGylation on the stability of liposomes during nebulisation and in lung surfactant

scientific article published in September 2006

Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres

scientific article

Effect of chitosan structure properties and molecular weight on the intranasal absorption of tetramethylpyrazine phosphate in rats

scientific article published on 8 July 2008

Effect of poly(ethylene imine) molecular weight and pegylation on organ distribution and pharmacokinetics of polyplexes with oligodeoxynucleotides in mice.

scientific article

Effects of cell-penetrating peptides and pegylation on transfection efficiency of polyethylenimine in mouse lungs

scientific article

Effects of different application parameters on penetration characteristics and arterial vessel wall integrity after local nanoparticle delivery using a porous balloon catheter

scientific article

Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method

scientific article

Efficiency of polyethylenimines and polyethylenimine-graft-poly (ethylene glycol) block copolymers to protect oligonucleotides against enzymatic degradation

scientific article published in May 2004

Efficient and Tumor Targeted siRNA Delivery by Polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate (PEI-PCL-PEG-Fol).

scientific article published on 7 December 2015

Enhanced gene expression and reduced toxicity in mice using polyplexes of low-molecular-weight poly(ethylene imine) for pulmonary gene delivery

scientific article

Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers

scientific article

Enzyme-responsive surface erosion of poly(ethylene carbonate) for controlled drug release

scientific article published on 30 April 2013

Factors influencing polycation/siRNA colloidal stability toward aerosol lung delivery

scientific article published on 6 September 2011

Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy

scientific article

Feasibility of macrophage mediated on-demand drug release from surface eroding poly(ethylene carbonate).

scientific article published on 12 February 2014

Folic acid-decorated nanocomposites prepared by a simple solvent displacement method

scientific article published on 20 February 2012

Functionalized polyglycerol amine nanogels as nanocarriers for DNA.

scientific article

Galactose-PEI-DNA complexes for targeted gene delivery: degree of substitution affects complex size and transfection efficiency

scientific article published on February 2003

HER2 targeted polyplexes: the effect of polyplex composition and conjugation chemistry on in vitro and in vivo characteristics

scientific article published on 23 November 2007

Hydrolytic degradation of poly(lactide-co-glycolide) films: effect of oligomers on degradation rate and crystallinity ⬇️

scientific article published on November 6, 2003

Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: formulation aspects and stability

scientific article published on 27 December 2006

Imidazole and dimethyl aminopropyl-functionalized hyperbranched polymers for nucleic acid transfection

scientific article

Impact of lyoprotectants for the stabilization of biodegradable nanoparticles on the performance of air-jet, ultrasonic, and vibrating-mesh nebulizers.

scientific article published on 20 July 2012

In situ forming nimodipine depot system based on microparticles for the treatment of posthemorrhagic cerebral vasospasm

scientific article published on 5 January 2013

In situ forming parenteral depot systems based on poly(ethylene carbonate): effect of polymer molecular weight on model protein release

scientific article published on 19 June 2013

In vitro and in vivo correlation of buserelin release from biodegradable implants using statistical moment analysis

scientific article published in January 2004

In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles

scientific article

In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application

scientific article

In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis

scientific article

In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure

scientific article

In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes

scientific article

Influence of amine-modified poly(vinyl alcohol)s on vibrating-membrane nebulizer performance and lung toxicity

scientific article published on 02 March 2016

Influence of morphology and drug distribution on the release process of FITC-dextran-loaded microspheres prepared with different types of PLGA.

scientific article

Influence of particle size and material properties on mucociliary clearance from the airways

scientific article published on August 2010

Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes

scientific article published on September 2006

Insulin containing nanocomplexes formed by self-assembly from biodegradable amine-modified poly(vinyl alcohol)-graft-poly(L-lactide): bioavailability and nasal tolerability in rats

scientific article published on 26 August 2005

Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine).

scientific article

Integrin targeting using RGD-PEI conjugates for in vitro gene transfer

scientific article

Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments

scientific article

Loading of tetanus toxoid to biodegradable nanoparticles from branched poly(sulfobutyl-polyvinyl alcohol)-g-(lactide-co-glycolide) nanoparticles by protein adsorption: a mechanistic study

scientific article published in August 2002

Low Molecular Weight pDMAEMA-block-pHEMA Block-Copolymers Synthesized via RAFT-Polymerization: Potential Non-Viral Gene Delivery Agents?

scientific article published on 28 March 2011

Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice

scientific article published in January 2004

Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine

scientific article

Lyophilised ready-to-use formulations of PEG-PCL-PEI nano-carriers for siRNA delivery

scientific article

Modular synthesis of folate conjugated ternary copolymers: polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate for targeted gene delivery

scientific article

Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems

scientific article

Nanocomposites of lung surfactant and biodegradable cationic nanoparticles improve transfection efficiency to lung cells

scientific article

Nanofibers by green electrospinning of aqueous suspensions of biodegradable block copolyesters for applications in medicine, pharmacy and agriculture

scientific article

Nanoparticles for paclitaxel delivery: a comparative study of different types of dendritic polyesters and their degradation behavior

scientific article published on 21 January 2011

Nanosized insulin-complexes based on biodegradable amine-modified graft polyesters poly[vinyl-3-(diethylamino)-propylcarbamate-co-(vinyl acetate)-co-(vinyl alcohol)]-graft-poly(L-lactic acid): protection against enzymatic degradation, interaction wi

scientific article published on 20 October 2006

Nasal absorption and local tissue reaction of insulin nanocomplexes of trimethyl chitosan derivatives in rats

scientific article published on May 2010

Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features

scientific article

Nebulization performance of biodegradable sildenafil-loaded nanoparticles using the Aeroneb Pro: formulation aspects and nanoparticle stability to nebulization

scientific article published on 6 October 2011

Non-ionic dendritic glycerol-based amphiphiles: novel excipients for the solubilization of poorly water-soluble anticancer drug Sagopilone

scientific article published on 25 February 2010

Nonviral pulmonary delivery of siRNA.

scientific article

Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance

scientific article published in July 2009

Novel 'nano in nano' composites for sustained drug delivery: biodegradable nanoparticles encapsulated into nanofiber non-wovens

scientific article published on 7 September 2010

Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: synthesis, stability, cytotoxicity and MR imaging

scientific article published on 18 February 2011

Optimising the self-assembly of siRNA loaded PEG-PCL-lPEI nano-carriers employing different preparation techniques

scientific article

Optimized preparation of pDNA/poly(ethylene imine) polyplexes using a microfluidic system

scientific article

PEGylated poly(ethylene imine) copolymer-delivered siRNA inhibits HIV replication in vitro

scientific article published on 10 September 2011

PEGylation affects cytotoxicity and cell-compatibility of poly(ethylene imine) for lung application: structure-function relationships

scientific article published on 12 October 2009

PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice

scientific article

Paclitaxel releasing films consisting of poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) and their potential as biodegradable stent coatings

scientific article published on 8 February 2006

Pegylated polyethylenimine-Fab' antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells.

scientific article published on September 2003

Perfectly shaped siRNA delivery

scientific article published on December 2010

Peroral delivery of insulin using chitosan derivatives: a comparative study of polyelectrolyte nanocomplexes and nanoparticles

scientific article

Pharmaceutical care for patients with ischemic stroke: improving the patients quality of life

scientific article published on 25 July 2009

Physicochemical and biological characterization of polyethylenimine-graft-poly(ethylene glycol) block copolymers as a delivery system for oligonucleotides and ribozymes

scientific article

Physicochemical properties and biocompatibility of N-trimethyl chitosan: effect of quaternization and dimethylation

scientific article

Poly(diallyldimethylammonium chlorides) and their N-methyl-N-vinylacetamide copolymer-based DNA-polyplexes: role of molecular weight and charge density in complex formation, stability, and in vitro activity

scientific article published on August 2004

Poly(ethylene carbonate) as a surface-eroding biomaterial for in situ forming parenteral drug delivery systems: a feasibility study

scientific article published on 19 July 2010

Poly(ethylene imine) nanocarriers do not induce mutations nor oxidative DNA damage in vitro in MutaMouse FE1 cells

scientific article published on 7 April 2011

Poly(ethylenimine-co-L-lactamide-co-succinamide): a biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery

scientific article published on July 2002

Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings

scientific article published in May 2005

Poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) nanoparticles for local delivery of paclitaxel for restenosis treatment

scientific article

Polycationic triazine-based dendrimers: effect of peripheral groups on transfection efficiency

scientific article published on January 2009

Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system

scientific article published on July 2002

Polyfluorene nanoparticles coated with folate-functionalized triblock copolymer: effective agents for targeted cell imaging

scientific article published on 27 August 2012

Polymer nanoparticle-based controlled pulmonary drug delivery.

scientific article

Polymeric micelles for parenteral delivery of sagopilone: physicochemical characterization, novel formulation approaches and their toxicity assessment in vitro as well as in vivo

scientific article published on 24 February 2010

Potential of the isolated lung technique for the examination of sildenafil absorption from lung-delivered poly(lactide-co-glycolide) microparticles

scientific article published on 2 February 2016

Predicting protein instability in sustained protein delivery systems using spectral-phase interference

scientific article published on 2 December 2011

Preparation of nanoparticles by solvent displacement for drug delivery: a shift in the "ouzo region" upon drug loading

scientific article published on 22 June 2010

Prolonged vasodilatory response to nanoencapsulated sildenafil in pulmonary hypertension.

scientific article published on 19 September 2015

Prospects for cationic polymers in gene and oligonucleotide therapy against cancer

scientific article

Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model

scientific article published on 19 September 2008

Pulmonary gene delivery using polymeric nonviral vectors

scientific article

Pulmonary targeting with biodegradable salbutamol-loaded nanoparticles

scientific article published in February 2010

Quo vadis polyplex?

scientific article

Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives

scientific article

Reflectance infrared spectroscopy for in-line monitoring of nicotine during a coating process for an oral thin film.

scientific article

Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and enoxaparin

scientific article

Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and insulin

scientific article

Solubilization of sagopilone, a poorly water-soluble anticancer drug, using polymeric micelles for parenteral delivery

scientific article published on 25 January 2010

Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emissi

scientific article

Stabilization of aerosolizable nano-carriers by freeze-drying

scientific article published on 8 October 2008

Stabilization of oligonucleotide-polyethylenimine complexes by freeze-drying: physicochemical and biological characterization

scientific article published in February 2004

Star-shaped poly(ethylene glycol)-block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines.

scientific article published in September 2002

Supramolecular gene delivery vectors showing enhanced transgene expression and good biocompatibility

scientific article published on March 2005

Surfactant-free redispersible nanoparticles in fast-dissolving composite microcarriers for dry-powder inhalation

scientific article

Synthesis of a new potential biodegradable disulfide containing poly(ethylene imine)-poly(ethylene glycol) copolymer cross-linked with click cluster for gene delivery

scientific article published on 23 March 2011

Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers

scientific article

Targeting the blind spot of polycationic nanocarrier-based siRNA delivery

scientific article published on 9 October 2012

Tetanus toxoid microspheres consisting of biodegradable poly(lactide-co-glycolide)- and ABA-triblock-copolymers: immune response in mice

scientific article published on 01 March 2002

The Macrostopper Route: A New Synthesis Concept Leading Exclusively to Diblock Copolymers with Enhanced DNA Condensation Potential

The depolymerization of chitosan: effects on physicochemical and biological properties

scientific article published on August 2004

The potential of glycol chitosan nanoparticles as carrier for low water soluble drugs

scientific article

The role of branched polyesters and their modifications in the development of modern drug delivery vehicles

scientific article

The role of mucoadhesion of trimethyl chitosan and PEGylated trimethyl chitosan nanocomplexes in insulin uptake

scientific article published on December 2009

The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-kappaB decoy in mice

scientific article published on 01 June 2002

Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications

scientific article

Triazine Dendrimers for DNA and siRNA Delivery: Progress, Challenges, and Opportunities

scientific article published on 14 June 2012

Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity

scientific article

Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity

scientific article published on August 2010

Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells

scientific article

Variation of peptide transporter (PepT1 and HPT1) expression in Caco-2 cells as a function of cell origin

scientific article

siRNA delivery to the lung: what's new?

scientific article

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