List of works by Jonathan T Butcher

Active tissue stiffness modulation controls valve interstitial cell phenotype and osteogenic potential in 3D culture

scientific article published on 03 March 2016

Aortic valve disease and treatment: the need for naturally engineered solutions.

scientific article published on 31 January 2011

Award Winner in the Young Investigator Category, 2017 Society for Biomaterials Annual Meeting and Exposition, Minneapolis, MN, April 05-08, 2017: Lymph node stiffness-mimicking hydrogels regulate human B-cell lymphoma growth and cell surface recepto

scientific article published on 8 February 2017

Biofabrication of thick vascularized neo-pedicle flaps for reconstructive surgery

scientific article published on 21 May 2019

Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves

scientific article published on 16 June 2016

Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation

scientific article published on 15 July 2015

Cadherin-11 expression patterns in heart valves associate with key functions during embryonic cushion formation, valve maturation and calcification.

scientific article published on 20 December 2013

Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis

scientific article published on 01 July 2019

Cardiac developmental toxicity

scientific article published on December 2011

Cardiac regeneration following cryoinjury in the adult zebrafish targets a maturation-specific biomechanical remodeling program

scientific article published in Scientific Reports

Cohort-based multiscale analysis of hemodynamic-driven growth and remodeling of the embryonic pharyngeal arch arteries

scientific article published on 17 October 2018

Comparison of Mesenchymal Stem Cell Source Differentiation Toward Human Pediatric Aortic Valve Interstitial Cells within 3D Engineered Matrices.

scientific article published on 13 April 2015

Computational fluid dynamics of developing avian outflow tract heart valves.

scientific article

Computational simulation of hemodynamic-driven growth and remodeling of embryonic atrioventricular valves

scientific article published on 7 August 2012

Correction: Endothelial-derived oxidative stress drives myofibroblastic activation and calcification of the aortic valve.

scientific article published on 18 May 2015

Crystallinity of hydroxyapatite drives myofibroblastic activation and calcification in aortic valves.

scientific article published on 2 March 2018

Current progress in tissue engineering of heart valves: multiscale problems, multiscale solutions

scientific article published on June 2015

Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve

scientific article published on 22 December 2015

Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture.

scientific article published on 11 January 2012

Developmental Mechanisms of Aortic Valve Malformation and Disease

scientific article published on 09 December 2016

Effects of shear stress pattern and magnitude on mesenchymal transformation and invasion of aortic valve endothelial cells

scientific article

Endothelial retention and phenotype on carbonized cardiovascular implant surfaces.

scientific article published on 20 June 2014

Endothelial-derived oxidative stress drives myofibroblastic activation and calcification of the aortic valve

scientific article published on 13 April 2015

Equibiaxial strain stimulates fibroblastic phenotype shift in smooth muscle cells in an engineered tissue model of the aortic wall.

scientific article published on 27 June 2006

Fabrication of Aligned Nanofiber Polymer Yarn Networks for Anisotropic Soft Tissue Scaffolds.

scientific article published on 15 June 2016

Growth and hemodynamics after early embryonic aortic arch occlusion

scientific article

Heart function and hemodynamic analysis for zebrafish embryos.

scientific article published on March 2017

Heterogeneous susceptibility of valve endothelial cells to mesenchymal transformation in response to TNFα.

scientific article published on 27 August 2013

Hierarchical approaches for systems modeling in cardiac development.

scientific article published on 5 March 2013

Inflammatory cytokines promote mesenchymal transformation in embryonic and adult valve endothelial cells

scientific article published on 25 October 2012

Isolation and culture of avian embryonic valvular progenitor cells

scientific article

JuPOETs: a constrained multiobjective optimization approach to estimate biochemical model ensembles in the Julia programming language.

scientific article

Living nano-micro fibrous woven fabric/hydrogel composite scaffolds for heart valve engineering.

scientific article

Matrix stiffening promotes a tumor vasculature phenotype.

scientific article published on 29 December 2016

Mechanical regulation of cardiac development

scientific article

Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis.

scientific article published on 22 December 2017

Method for non-optical quantification of in situ local soft tissue biomechanics.

scientific article

Micro/nano-computed tomography technology for quantitative dynamic, multi-scale imaging of morphogenesis.

scientific article published on January 2015

Mitral valve disease--morphology and mechanisms

scientific article

Monocytes and Macrophages in Heart Valves: Uninvited Guests or Critical Performers?

scientific article published on 05 March 2018

Nanofiber-structured hydrogel yarns with pH-response capacity and cardiomyocyte-drivability for bio-microactuator application.

scientific article published on 18 July 2017

Notch-Tnf signalling is required for development and homeostasis of arterial valves

scientific article published on 21 October 2015

OCT4-mediated inflammation induces cell reprogramming at the origin of cardiac valve development and calcification

scientific article published on 05 November 2021

Optimizing Photo-Encapsulation Viability of Heart Valve Cell Types in 3D Printable Composite Hydrogels

scientific article published on 22 April 2016

Quantitative optimization of solid freeform deposition of aqueous hydrogels.

scientific article published on 2 May 2013

Quantitative volumetric analysis of cardiac morphogenesis assessed through micro-computed tomography.

scientific article

ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm

scientific article published on 19 November 2018

Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds

scientific article

Serotonin potentiates transforming growth factor-beta3 induced biomechanical remodeling in avian embryonic atrioventricular valves.

scientific article

Spatial Regulation of Valve Interstitial Cell Phenotypes within Three-Dimensional Micropatterned Hydrogels

scientific article published on 04 February 2019

Systematic Analysis of the Smooth Muscle Wall Phenotype of the Pharyngeal Arch Arteries during their Reorganization into the Great Vessels and its association with Hemodynamics

scientific article published on 09 November 2018

The living aortic valve: From molecules to function.

scientific article

The root problem of heart valve engineering

scientific article published on 01 May 2018

Three-dimensional printed trileaflet valve conduits using biological hydrogels and human valve interstitial cells.

scientific article published on 12 December 2013

Transcriptional Profiles of Valvular and Vascular Endothelial Cells Reveal Phenotypic Differences

scientific article published on 17 November 2005

Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects.

scientific article

Uncovering transcriptional dark matter via gene annotation independent single-cell RNA sequencing analysis

scientific article published on 12 April 2021

Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments.

scientific article published on 29 April 2004

Valve interstitial cell tensional homeostasis directs calcification and extracellular matrix remodeling processes via RhoA signaling ⬇️

scientific article published on 29 July 2016

Valvular endothelial cells and the mechanoregulation of valvular pathology.

scientific article published on August 2007

Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress.

scientific article

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