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List of works by Mario Faúndez

A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections

scientific article published on 19 July 2018

Buthionine sulfoximine has anti-Trypanosoma cruzi activity in a murine model of acute Chagas' disease and enhances the efficacy of nifurtimox.

scientific article published on 10 March 2008

Buthionine sulfoximine increases the toxicity of nifurtimox and benznidazole to Trypanosoma cruzi.

scientific article

Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor

scientific article published on 27 January 2017

Copper modifies liver microsomal UDP-glucuronyltransferase activity through different and opposite mechanisms

scientific article published on 30 December 2006

Effect of alpha lipoic acid on leukotriene A4 hydrolase.

scientific article published on 26 January 2017

In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.

scientific article published in September 2004

Inhibition of cytosolic glutathione S-transferase activity from rat liver by copper

scientific article published on 25 August 2006

Inhibitory effect of nordihydroguaiaretic acid and its tetra-acetylated derivative on respiration and growth of adenocarcinoma TA3 and its multiresistant variant TA3MTX-R.

scientific article

Liver microsomal biotransformation of nitro-aryl drugs: mechanism for potential oxidative stress induction.

scientific article published on November 2004

Mechanisms underlying the inhibition of the cytochrome P450 system by copper ions.

scientific article published in November 2009

Melatonin protects the cytochrome P450 system through a novel antioxidant mechanism.

scientific article published on 17 March 2010

Microsomal UDP-glucuronyltransferase in rat liver: oxidative activation

scientific article published on June 2005

Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host.

scientific article

NADPH oxidase activity: Spectrophotometric determination of superoxide using pyrogallol red.

scientific article published on 23 August 2017

Natural and synthetic naphthoquinones active against Trypanosoma cruzi: an initial step towards new drugs for Chagas disease

scientific article published on January 2011

New imidoyl-indazole platinum (II) complexes as potential anticancer agents: Synthesis, evaluation of cytotoxicity, cell death and experimental-theoretical DNA interaction studies.

scientific article

Novel FXa Inhibitor Identification through Integration of Ligand- and Structure-Based Approaches.

scientific article

Possible mechanisms underlying copper-induced damage in biological membranes leading to cellular toxicity.

scientific article

Protective role of acetylsalicylic acid in experimental Trypanosoma cruzi infection: evidence of a 15-epi-lipoxin A₄-mediated effect.

scientific article

Pyrogallol red oxidation induced by superoxide radicals: application to evaluate redox cycling of nitro compounds.

scientific article published in September 2011

Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching

scientific article published on 27 April 2019

Synthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core.

scientific article published on 3 April 2018

Synthesis and pharmacophore modelling of 2,6,9-trisubstituted purine derivatives and their potential role as apoptosis-inducing agents in cancer cell lines

scientific article published on 15 April 2015

Synthesis of 4(3H)quinazolinimines with selective cytotoxic effect on human acute promyelocytic leukemia cells

scientific article

Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor

scientific article published on 5 August 2016

Trypanosoma cruzi: In vitro effect of aspirin with nifurtimox and benznidazole

scientific article

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