List of works by Benjamin T Goult

A Novel Mechanism for Calmodulin-Dependent Inactivation of Transient Receptor Potential Vanilloid 6. ⬇️

scientific article published on 5 March 2018

A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation.

scientific article published on 10 January 2012

A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration.

scientific article

A novel interaction between FRMD7 and CASK: evidence for a causal role in idiopathic infantile nystagmus.

scientific article published on 12 February 2013

Adhesions Assemble!-Autoinhibition as a Major Regulatory Mechanism of Integrin-Mediated Adhesion

scientific article published on 17 December 2019

Alternative molecular mechanisms for force transmission at adherens junctions via β-catenin-vinculin interaction

scientific article published in 2024

Cancer associated talin point mutations disorganise cell adhesion and migration

scientific article published on 11 January 2021

Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin

scientific article

Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex.

scientific article

Direct binding of Talin to Rap1 is required for cell-ECM adhesion in Drosophila

scientific article published on 18 December 2018

Force-Dependent Binding Constants

scientific article published on 01 August 2019

Force-Dependent Regulation of Talin-KANK1 Complex at Focal Adhesions

scientific article published on 13 August 2019

High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained

scientific article published on 09 October 2019

Investigation of the Filamin A-Dependent Mechanisms of Tissue Factor Incorporation into Microvesicles.

scientific article published on 10 October 2017

Kindlin-1 Regulates Epidermal Growth Factor Receptor Signaling

scientific article published on 21 September 2018

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex ⬇️

scientific article published on 31 May 2016

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

scientific article published on 09 April 2014

Myosin-X and talin modulate integrin activity at filopodia tips

scientific article published on 01 September 2021

Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3(Alp6)

scientific article published on 04 September 2013

NMR assignment of the C-terminal actin-binding domain of talin.

scientific article published on 22 December 2007

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

scientific article

Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation

scientific article published on 01 September 2018

Small-angle X-ray scattering and NMR studies of the conformation of the PDZ region of SAP97 and its interactions with Kir2.1.

scientific article published on 16 November 2007

Structural Determinants of Integrin Binding to the Talin Rod

scientific article

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

scientific article

Structure calculation, refinement and validation using CcpNmr Analysis.

scientific article published on January 2015

Talin Dependent Mechanosensitivity of Cell Focal Adhesions

scientific article

Talin as a mechanosensitive signaling hub

scientific article published on 25 September 2018

Talin autoinhibition is required for morphogenesis

scientific article published on 5 September 2013

Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics

scientific article published on 4 April 2012

Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.

scientific article

Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.

scientific article published on 13 July 2016

Talin2-mediated traction force drives matrix degradation and cell invasion.

scientific article published on October 2016

The 1H, 13C and 15N backbone and side-chain assignment of the RRM domain of SC35, a regulator of pre-mRNA splicing.

scientific article published on 12 August 2010

The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel.

scientific article published on 27 March 2018

The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation

scientific article

The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

scientific article

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain

scientific article

The mechanical response of talin

scientific article published on 07 July 2016

The solution structure of a domain from the Neisseria meningitidis lipoprotein PilP reveals a new beta-sandwich fold

scientific article published on 01 September 2006

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.

scientific article

The tale of two talins - two isoforms to fine-tune integrin signalling

scientific article published on 18 May 2018

The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering

scientific article (publication date: November 2014)

Vinculin controls talin engagement with the actomyosin machinery.

scientific article

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