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List of works by Olivier Feron

(89)Zr-labeled anti-endoglin antibody-targeted gold nanoparticles for imaging cancer: implications for future cancer therapy.

scientific article published on 18 February 2014

19F NMR in vivo spectroscopy reflects the effectiveness of perfusion-enhancing vascular modifiers for improving gemcitabine chemotherapy.

scientific article published in January 2008

A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling

scientific article

A mitochondrial switch promotes tumor metastasis.

scientific article

A new ER-specific photosensitizer unravels (1)O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT.

scientific article published on 21 December 2015

A new method combining sequential immunoaffinity depletion and differential in gel electrophoresis to identify autoantibodies as cancer biomarkers

scientific article published on 2 August 2013

A roadmap for interpreting (13)C metabolite labeling patterns from cells

scientific article

Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation.

scientific article published on August 2016

Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing.

scientific article published on April 2010

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

scientific article

Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation

scientific article published on 18 March 2019

Antibody-functionalized gold nanoparticles as tumor-targeting radiosensitizers for proton therapy

scientific article published on 24 January 2019

Antibody-functionalized nanoparticles for imaging cancer: influence of conjugation to gold nanoparticles on the biodistribution of 89Zr-labeled cetuximab in mice

scientific article published on September 2013

Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption

scientific article published on 03 October 2018

Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux

scientific article published on 26 March 2014

Antitumor effects of in vivo caveolin gene delivery are associated with the inhibition of the proangiogenic and vasodilatory effects of nitric oxide.

scientific article published on 28 December 2004

Assessment of melanoma extent and melanoma metastases invasion using electron paramagnetic resonance and bioluminescence imaging.

scientific article

Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species.

scientific article

Biodistribution of (125)I-labeled anti-endoglin antibody using SPECT/CT imaging: Impact of in vivo deiodination on tumor accumulation in mice.

scientific article published on 29 March 2016

Both host and graft vessels contribute to revascularization of xenografted human ovarian tissue in a murine model

scientific article

Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling

scientific article published on 18 January 2017

Cancer heterogeneity is not compatible with one unique cancer cell metabolic map

scientific article

Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates beta-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction.

scientific article

Caveolin plays a central role in endothelial progenitor cell mobilization and homing in SDF-1-driven postischemic vasculogenesis

scientific journal article

Caveolin-1 is critical for the maturation of tumor blood vessels through the regulation of both endothelial tube formation and mural cell recruitment

scientific article

Caveolins and the regulation of endothelial nitric oxide synthase in the heart

scientific article

Challenges and Opportunities in the Development of Serine Synthetic Pathway Inhibitors for Cancer Therapy

scientific article published on 13 December 2016

Changes in Hsp90 expression determine the effects of cyclosporine A on the NO pathway in rat myocardium

scientific article published on 01 September 2003

Comparison of X-ray and alpha particle effects on a human cancer and endothelial cells: survival curves and gene expression profiles.

scientific article published on 26 March 2013

Comparison of methods for measuring oxygen consumption in tumor cells in vitro.

scientific article published on 18 September 2009

Comparison of the clonogenic survival of A549 non-small cell lung adenocarcinoma cells after irradiation with low-dose-rate beta particles and high-dose-rate X-rays

scientific article

Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies

scientific article

Contribution of oxygenation to BOLD contrast in exercising muscle

scientific article published on 01 August 2004

Cycling hypoxia induces a specific amplified inflammatory phenotype in endothelial cells and enhances tumor-promoting inflammation in vivo

scientific article

Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway

scientific article published on 21 January 2020

Cycling hypoxia: A key feature of the tumor microenvironment

scientific article published on 22 June 2016

Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method

scientific article published on 14 December 2015

Delivery of soluble VEGF receptor 1 (sFlt1) by gene electrotransfer as a new antiangiogenic cancer therapy.

scientific article published on 13 May 2011

Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells

scientific article published on 09 December 2020

Differential influence of anticancer treatments and angiogenesis on the seric titer of autoantibody used as tumor and metastasis biomarker

scientific article

Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction.

scientific article

Dynamic contrast-enhanced MRI in mouse tumors at 11.7 T: comparison of three contrast agents with different molecular weights to assess the early effects of combretastatin A4.

scientific article published in November 2014

Early reoxygenation in tumors after irradiation: determining factors and consequences for radiotherapy regimens using daily multiple fractions

scientific article

Effects of BM-573 on Endothelial Dependent Relaxation and Increased Blood Pressure at Early Stages of Atherosclerosis

scientific article

Effects of vascular endothelial growth factor on the lymphocyte-endothelium interactions: identification of caveolin-1 and nitric oxide as control points of endothelial cell anergy

scientific article published on 01 February 2007

Electron paramagnetic resonance as a sensitive tool to assess the iron oxide content in cells for MRI cell labeling studies.

scientific article

Emerging roles of lipid metabolism in cancer progression

scientific article published on 11 April 2017

Endothelial beta3-adrenoreceptors mediate nitric oxide-dependent vasorelaxation of coronary microvessels in response to the third-generation beta-blocker nebivolol.

scientific article published in August 2005

Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force ⬇️

scientific article published on February 1, 2013

Endothelial nitric oxide synthase overexpression provides a functionally relevant angiogenic switch in hibernating pig myocardium.

scientific article published on 23 March 2007

Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment

scientific article

Ffar2 expression regulates leukaemic cell growth in vivo.

scientific article published on 5 September 2017

Fusicoccin a, a phytotoxic carbotricyclic diterpene glucoside of fungal origin, reduces proliferation and invasion of glioblastoma cells by targeting multiple tyrosine kinases

scientific article published on April 2013

Galectin-1 in melanoma biology and related neo-angiogenesis processes.

scientific article published on 24 May 2012

Glucocorticoids modulate tumor radiation response through a decrease in tumor oxygen consumption

scientific article published on 01 January 2007

Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration

scientific article published on 28 October 2013

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver

scientific article

Harnessing the response to tissue hypoxia: HIF-1 alpha and therapeutic angiogenesis

scientific article

Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.

scientific article

Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase

scientific article published on 26 April 2013

High field magnetic resonance imaging of rodents in cardiovascular research.

scientific article

Hypoxia integration in the serological proteome analysis unmasks tumor antigens and fosters the identification of anti-phospho-eEF2 antibodies as potential cancer biomarkers

scientific article

Hypoxia modulates the differentiation potential of stem cells of the apical papilla.

scientific article published on 13 June 2014

In vivo visualization and ex vivo quantification of murine breast cancer cells in the mouse brain using MRI cell tracking and electron paramagnetic resonance.

scientific article

Influence of cell detachment on the respiration rate of tumor and endothelial cells

scientific article

Inhibition of glucose metabolism prevents glycosylation of the glutamine transporter ASCT2 and promotes compensatory LAT1 upregulation in leukemia cells

scientific article published on 17 June 2016

Innate immunity and angiogenesis

scientific article

Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption

scientific article

Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects.

scientific article published on 23 March 2018

Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight

scientific article published on 16 May 2015

Iodine deficiency induces a thyroid stimulating hormone-independent early phase of microvascular reshaping in the thyroid

scientific article

Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis

scientific article published on 05 October 2009

Iron oxide particles covered with hexapeptides targeted at phosphatidylserine as MR biomarkers of tumor cell death.

scientific article published on September 2010

LDV peptidomimetics equipped with biotinylated spacer-arms: synthesis and biological evaluation on CCRF-CEM cell line

scientific article

LET-dependent radiosensitization effects of gold nanoparticles for proton irradiation.

scientific article published on 3 October 2016

Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells

scientific article published in 2012

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis

scientific article published on 7 February 2011

Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice.

scientific article published on 3 June 2012

Liposomal Hsp90 cDNA induces neovascularization via nitric oxide in chronic ischemia.

scientific article published in February 2005

MRI Assessment of Cardiomyopathy Induced by β1-Adrenoreceptor Autoantibodies and Protection Through β3-Adrenoreceptor Overexpression.

scientific article published on 09 March 2017

Mapping of oxygen by imaging lipids relaxation enhancement: a potential sensitive endogenous MRI contrast to map variations in tissue oxygenation

scientific article

Mechanism of reoxygenation after antiangiogenic therapy using SU5416 and its importance for guiding combined antitumor therapy

scientific article published on 01 October 2006

Mechanisms of pericyte recruitment in tumour angiogenesis: a new role for metalloproteinases.

scientific article

Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.

scientific article

Metallic nanoparticles irradiated by low-energy protons for radiation therapy: Are there significant physical effects to enhance the dose delivery?

scientific article

Mice that lack endothelial nitric oxide synthase are protected against functional and structural modifications induced by acute peritonitis.

scientific article published in December 2003

Moderate caveolin-1 downregulation prevents NADPH oxidase-dependent endothelial nitric oxide synthase uncoupling by angiotensin II in endothelial cells

scientific article published on 09 June 2011

Molecular electron paramagnetic resonance imaging of melanin in melanomas: a proof-of-concept

scientific article published on 01 March 2008

Monte Carlo Calculation of Radioimmunotherapy with (90)Y-, (177)Lu-, (131)I-, (124)I-, and (188)Re-Nanoobjects: Choice of the Best Radionuclide for Solid Tumour Treatment by Using TCP and NTCP Concepts.

scientific article published on 2 June 2015

Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.

scientific article published on December 2016

Multimodal assessment of early tumor response to chemotherapy: comparison between diffusion‐weighted MRI, 1H‐MR spectroscopy of choline and USPIO particles targeted at cell death ⬇️

scientific article published on August 23, 2011

Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence.

scientific article published on March 2014

Multimodal imaging of tumor response to sorafenib combined with radiation therapy: comparison between diffusion-weighted MRI, choline spectroscopy and 18F-FLT PET imaging.

scientific article published on May 2013

Multimodality Imaging Identifies Distinct Metabolic Profiles In Vitro and In Vivo

scientific article

Nitric oxide delivery to cancer: why and how?

scientific article published on 17 January 2009

Nitric oxide synthase isoforms play distinct roles during acute peritonitis.

scientific article published on 25 August 2009

Nitric oxide-mediated increase in tumor blood flow and oxygenation of tumors implanted in muscles stimulated by electric pulses

scientific article

Optimized acriflavine-loaded lipid nanocapsules as a safe and effective delivery system to treat breast cancer

scientific article published on 17 September 2018

PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation

scientific article

Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma

scientific article published on 27 February 2020

Piperlongumine increases sensitivity of colorectal cancer cells to radiation: Involvement of ROS production via dual inhibition of glutathione and thioredoxin systems

scientific article published on 18 February 2019

Potential of memory T cells in bridging preoperative chemoradiation and immunotherapy in rectal cancer

scientific article published on 02 June 2018

Potentiation of radiotherapy by a localized antiangiogenic gene therapy

scientific article

Preclinical Evaluation of White Led-Activated Non-porphyrinic Photosensitizer OR141 in 3D Tumor Spheroids and Mouse Skin Lesions

scientific article published on 21 September 2018

Preconditioned endothelial progenitor cells reduce formation of melanoma metastases through SPARC-driven cell-cell interactions and endocytosis

scientific article published on 26 May 2011

Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.

scientific article published on 13 July 2009

Radioimmunotherapy with radioactive nanoparticles: biological doses and treatment efficiency for vascularized tumors with or without a central hypoxic area

scientific article published on 01 April 2010

Radioimmunotherapy with radioactive nanoparticles: first results of dosimetry for vascularized and necrosed solid tumors

scientific article published on 01 November 2007

Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation.

scientific article published on 21 May 2013

Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth.

scientific article published on 28 November 2015

Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.

scientific article

Reprogramming of energetic metabolism: increased expression and roles of pyruvate carboxylase in papillary thyroid cancer

scientific article published on 16 April 2019

Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation.

scientific article published on 9 July 2014

Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery.

scientific article published in June 2006

RhoA activation and interaction with Caveolin-1 are critical for pressure-induced myogenic tone in rat mesenteric resistance arteries.

scientific article published on 10 November 2006

Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells

scientific article published on 8 October 2013

Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells

scientific article published on 11 February 2008

Structure-Activity Relationships (SARs) of α-Ketothioamides as Inhibitors of Phosphoglycerate Dehydrogenase (PHGDH)

scientific article published on 22 January 2020

Surface properties and cell adhesion onto allylamine-plasma and amine-plasma coated glass coverslips ⬇️

scientific article published on 03 February 2011

Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells

scientific article

Synthesis of Novel β-Keto-Enol Derivatives Tethered Pyrazole, Pyridine and Furan as New Potential Antifungal and Anti-Breast Cancer Agents.

scientific article published on 10 November 2015

TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells

scientific article published on 23 January 2020

Targeting Endothelial Cell Metabolism by Inhibition of Pyruvate Dehydrogenase Kinase and Glutaminase-1

scientific article published on 15 October 2020

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.

scientific article

Targeting the tumor vascular compartment to improve conventional cancer therapy

scientific article

Targeting tumor stroma and exploiting mature tumor vasculature to improve anti-cancer drug delivery

scientific article published on 23 April 2007

Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment.

scientific article published in January 2005

The Blood Flow Shutdown Induced by Combretastatin A4 Impairs Gemcitabine Delivery in a Mouse Hepatocarcinoma

scientific article published on 23 December 2016

The NLRP3 Inflammasome Has a Critical Role in Peritoneal Dialysis-Related Peritonitis

scientific article published on 13 February 2017

The SIRT1/HIF2α axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy.

scientific article

The acidic tumor microenvironment promotes the reconversion of nitrite into nitric oxide: towards a new and safe radiosensitizing strategy.

scientific article published in May 2008

The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action

scientific article

The calcium channel blocker amlodipine promotes the unclamping of eNOS from caveolin in endothelial cells.

scientific article published on 27 April 2006

The double regulation of endothelial nitric oxide synthase by caveolae and caveolin: a paradox solved through the study of angiogenesis

scientific article

The increase in tumor oxygenation under carbogen breathing induces a decrease in the uptake of [(18)F]-fluoro-deoxy-glucose

scientific article published on 14 May 2015

The regulation of endothelial nitric oxide synthase by caveolin: a paradigm validated in vivo and shared by the 'endothelium-derived hyperpolarizing factor'.

scientific article published on 26 March 2010

The role of vessel maturation and vessel functionality in spontaneous fluctuations of T2*-weighted GRE signal within tumors

scientific article published in February 2006

Therapeutic potential of Focal Adhesion Kinase inhibition in small cell lung cancer

article

Thyroid status is a key modulator of tumor oxygenation: implication for radiation therapy.

scientific article published in October 2007

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

scientific article published on 24 August 2010

Transport and peripheral bioactivities of nitrogen oxides carried by red blood cell hemoglobin: role in oxygen delivery.

scientific article published on April 2007

Tumor reoxygenation following administration of Mitogen-Activated Protein Kinase inhibitors: a rationale for combination with radiation therapy.

scientific article

Tumor-penetrating peptides: a shift from magic bullets to magic guns.

scientific article published in June 2010

Tumour acidosis: from the passenger to the driver's seat.

scientific article

Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours.

scientific article published on 24 October 2013

Validation of a SPE HPLC-UV method for the quantification of a new ER-specific photosensitizer OR-141 in blood serum using total error concept

scientific article published on 13 April 2017

Variability of Mouse Left Ventricular Function Assessment by 11.7 Tesla MRI.

scientific article

Vascular Hypoxic Preconditioning Relies on TRPV4-Dependent Calcium Influx and Proper Intercellular Gap Junctions Communication

scientific article published in September 2012

Vascular caveolin deficiency supports the angiogenic effects of nitrite, a major end product of nitric oxide metabolism in tumors.

scientific article published on 30 June 2009

Vitamin E-based micelles enhance the anticancer activity of doxorubicin

scientific article published on 22 September 2014

α-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH).

scientific article published on 13 January 2017

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