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List of works by Fabian Chen

A randomised, placebo-controlled, first-in-human study of a novel clade C therapeutic peptide vaccine administered ex vivo to autologous white blood cells in HIV infected individuals

scientific article

CD8+ TCR Bias and Immunodominance in HIV-1 Infection

scientific article published on 24 April 2015

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection

scientific article published on 22 November 2017

Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope

scientific article published on 12 September 2012

Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells

scientific article published on 19 December 2012

Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B 2705-restricted CD8+ T cells

scientific article (publication date: October 2010)

Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects

scientific article published on May 2017

HIV control through a single nucleotide on the HLA-B locus

scientific article published on 15 August 2012

HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells

scientific article published in February 2010

HLA contributes to immune control of hepatitis B in HIV-positive African adults

article

HLA-A is a Predictor of Hepatitis B e Antigen Status in HIV-Positive African Adults

scientific article published on 9 December 2015

HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

scientific article published on July 2013

HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703

scientific article published on 15 April 2011

HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection

scientific article published on 6 September 2017

HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control

scientific article published on 16 November 2011

HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01

scientific article published on 17 July 2013

Improved quality of life with immediate versus deferred initiation of antiretroviral therapy in early asymptomatic HIV infection

scientific article published on 24 January 2017

Nef-specific CD8+ T cell responses contribute to HIV-1 immune control

scientific article

Non-immunogenicity of overlapping gag peptides pulsed on autologous cells after vaccination of HIV infected individuals ⬇️

scientific article published on 04 October 2013

PARV4 prevalence, phylogeny, immunology and coinfection with HIV, HBV and HCV in a multicentre African cohort

scientific article

Prevalence and Characteristics of Hepatitis B Virus (HBV) Coinfection among HIV-Positive Women in South Africa and Botswana

scientific article

Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

scientific article

Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient

scientific article published on 16 January 2018

Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities

scientific article published on 11 October 2017

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