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List of works by Michael R Zile

A comparative analysis of the results from 4 trials of beta-blocker therapy for heart failure: BEST, CIBIS-II, MERIT-HF, and COPERNICUS.

scientific article published on October 2003

A novel ultrasound predictor of pulmonary capillary wedge pressure assessed by the combination of left atrial volume and function: A speckle tracking echocardiography study

scientific article

A prediction model for sudden cardiac death in patients with heart failure and preserved ejection fraction

scientific article published on 10 October 2014

A putative placebo analysis of the effects of LCZ696 on clinical outcomes in heart failure

scientific article

A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: Evaluation of MCC-135 for left ventricul

scientific article published on 01 November 2007

A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: rationale and design of the evaluation o

scientific article published on 01 December 2005

Abnormal calcium homeostasis: one mechanism in diastolic heart failure

scientific article published on 01 July 2011

Abundance, localization, and functional correlates of the advanced glycation end-product carboxymethyl lysine in human myocardium.

scientific article published in November 2017

Accelerated LV remodeling after myocardial infarction in TIMP-1-deficient mice: effects of exogenous MMP inhibition

scientific article published on 01 January 2005

Activation of Inflammatory and Pro-Thrombotic Pathways in Acute Stress Cardiomyopathy.

scientific article published on 3 August 2017

Adverse left ventricular remodeling in community-dwelling older adults predicts incident heart failure and mortality

scientific article published on 3 September 2014

Age and SPARC change the extracellular matrix composition of the left ventricle

scientific article published on 24 March 2014

Age-Related Characteristics and Outcomes of Patients With Heart Failure With Preserved Ejection Fraction

scientific article published on 01 August 2019

Age-dependent alterations in fibrillar collagen content and myocardial diastolic function: role of SPARC in post-synthetic procollagen processing.

scientific article

Alterations in the myocardial capillary vasculature accompany tachycardia-induced cardiomyopathy

scientific article published on January 1, 1992

Anesthetic and Postoperative Protocols for a Canine Model of Reversible Left Ventricular Volume Overload ⬇️

scientific article published on January 1, 1991

Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction: Rationale and Design of the PARAGON-HF Trial

scientific article published on 26 June 2017

Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure

scientific article

Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction

scientific article published on 01 September 2019

Angiotensin-neprilysin inhibition versus enalapril in heart failure

scientific article (publication date: 11 September 2014)

Aortic valve resistance as an adjunct to the Gorlin formula in assessing the severity of aortic stenosis in symptomatic patients

scientific article published on December 1, 1992

Assessment of long-term effects of irbesartan on heart failure with preserved ejection fraction as measured by the minnesota living with heart failure questionnaire in the irbesartan in heart failure with preserved systolic function (I-PRESERVE) tri

scientific article published on 20 January 2012

Association between renal function and cardiovascular structure and function in heart failure with preserved ejection fraction

scientific article published on 30 June 2014

Association of Diabetes Mellitus on Cardiac Remodeling, Quality of Life, and Clinical Outcomes in Heart Failure With Reduced and Preserved Ejection Fraction

scientific article published on 21 August 2019

Attenuation of accelerated renal cystogenesis in Pkd1 mice by renin-angiotensin system blockade

scientific article

B-Type Natriuretic Peptide During Treatment With Sacubitril/Valsartan: The PARADIGM-HF Trial

scientific article published on 04 March 2019

Baroreflex Activation Therapy for the Treatment of Heart Failure With a Reduced Ejection Fraction

scientific article published on 14 May 2015

Baroreflex activation therapy for the treatment of heart failure with a reduced ejection fraction: safety and efficacy in patients with and without cardiac resynchronization therapy.

scientific article

Baroreflex activation therapy for the treatment of heart failure with reduced ejection fraction in patients with and without coronary artery disease.

scientific article

Baseline Characteristics of Patients With Heart Failure and Preserved Ejection Fraction in the PARAGON-HF Trial

scientific article published on 01 July 2018

Baseline characteristics and treatment of patients in prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial (PARADIGM-HF).

scientific article

Baseline plasma NT-proBNP and clinical characteristics: results from the irbesartan in heart failure with preserved ejection fraction trial

scientific article published on 4 November 2009

Bioactive Signaling in Next-Generation Pharmacotherapies for Heart Failure: A Review

scientific article published on 01 December 2018

Biomarkers of diastolic dysfunction and myocardial fibrosis: application to heart failure with a preserved ejection fraction.

scientific article published on 29 May 2013

Calpain inhibition preserves myocardial structure and function following myocardial infarction.

scientific article published on 04 September 2009

Cardiac macrophages promote diastolic dysfunction.

scientific article published on 16 January 2018

Cardiac structure and function and prognosis in heart failure with preserved ejection fraction: findings from the echocardiographic study of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) Trial

scientific article published on 13 August 2014

Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following pressure overload-induced hypertrophy.

scientific article

Cardiopulmonary Exercise Variables in Diastolic Versus Systolic Heart Failure

article

Cardiosphere-derived cells reverse heart failure with preserved ejection fraction (HFpEF) in rats by decreasing fibrosis and inflammation

scientific article published on January 2016

Changes in N-terminal pro-B-type natriuretic peptide levels and outcomes in heart failure with preserved ejection fraction: an analysis of the I-Preserve study.

scientific article published on 29 April 2015

Changes in myocardial blood flow during development of and recovery from tachycardia-induced cardiomyopathy ⬇️

scientific article published on 01 February 1992

Changes in the crystallographic structures of cardiac myosin filaments detected by polarization-dependent second harmonic generation microscopy

scientific article published on 07 June 2019

Characteristics and outcomes of patients with advanced chronic systolic heart failure receiving care at the Veterans Affairs versus other hospitals: insights from the Beta-blocker Evaluation of Survival Trial (BEST)

scientific article

Characterization of subgroups of heart failure patients with preserved ejection fraction with possible implications for prognosis and treatment response

scientific article

Chronic Baroreflex Activation: A Potential Therapeutic Approach to Heart Failure With Preserved Ejection Fraction ⬇️

scientific article published on October 29, 2010

Chronic ambulatory intracardiac pressures and future heart failure events.

scientific article published on 18 June 2010

Chronic kidney disease associated mortality in diastolic versus systolic heart failure: a propensity matched study.

scientific article published on 08 December 2006

Chronotropic incompetence: a common and progressive finding in pacemaker patients

scientific article published on 01 May 1992

Clinical and Echocardiographic Characteristics and Cardiovascular Outcomes According to Diabetes Status in Patients With Heart Failure and Preserved Ejection Fraction: A Report From the I-Preserve Trial (Irbesartan in Heart Failure With Preserved Ej

scientific article published on 04 January 2017

Clinical outcomes according to QRS duration and morphology in the irbesartan in patients with heart failure and preserved systolic function (I-PRESERVE) trial.

scientific article published on 15 May 2016

Combined immunoelectron microscopic and computer-assisted image analyses to detect advanced glycation end-products in human myocardium.

scientific article published on 19 May 2010

Comparing LCZ696 with enalapril according to baseline risk using the MAGGIC and EMPHASIS-HF risk scores: an analysis of mortality and morbidity in PARADIGM-HF.

scientific article published on November 2015

Comparison of outcomes after hospitalization for worsening heart failure, myocardial infarction, and stroke in patients with heart failure and reduced and preserved ejection fraction

scientific article

Contemporary Characteristics and Outcomes in Chagasic Heart Failure Compared With Other Nonischemic and Ischemic Cardiomyopathy

scientific article published in November 2017

Continuous aortic flow augmentation: a pilot study of hemodynamic and renal responses to a novel percutaneous intervention in decompensated heart failure.

scientific article published on 7 November 2005

Continuous hemodynamic monitoring in patients with mild to moderate heart failure: results of The Reducing Decompensation Events Utilizing Intracardiac Pressures in Patients With Chronic Heart Failure (REDUCEhf) trial

scientific article published on 10 August 2011

Contractile behavior of the left ventricle in diastolic heart failure: with emphasis on regional systolic function.

scientific article

Coronary blood flow after the regression of pressure-overload left ventricular hypertrophy

scientific article published on December 1, 1992

Correction: Multimorbidity in patients with heart failure from 11 Asian regions: A prospective cohort study using the ASIAN-HF registry

scientific article published on 25 May 2018

Could Modification of Titin Contribute to an Answer for Heart Failure With Preserved Ejection Fraction?

scientific article published on 14 September 2016

Declining Risk of Sudden Death in Heart Failure

scientific article

Dementia-related adverse events in PARADIGM-HF and other trials in heart failure with reduced ejection fraction

scientific article

Depressed contractile function due to canine mitral regurgitation improves after correction of the volume overload ⬇️

scientific article published on June 1, 1991

Developing therapies for heart failure with preserved ejection fraction: current state and future directions

scientific article

Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricle

scientific article published on 01 May 2004

Differential Impact of Heart Failure With Reduced Ejection Fraction on Men and Women

scientific article published on 01 January 2019

Digoxin and 30-day all-cause hospital admission in older patients with chronic diastolic heart failure

scientific article published on 23 September 2013

Discharge Hospice Referral and Lower 30-Day All-Cause Readmission in Medicare Beneficiaries Hospitalized for Heart Failure

scientific article published on 27 May 2015

Distinct roles for hindbrain and paraxial mesoderm in the induction and patterning of the inner ear revealed by a study of vitamin-A-deficient quail.

scientific article published in September 2005

Distribution of left ventricular ejection fraction in patients with ischemic and hypertensive heart disease and chronic heart failure

scientific article published on 01 November 2009

Does the Implantable Cardioverter-Defibrillator Benefit Vary With the Estimated Proportional Risk of Sudden Death in Heart Failure Patients?

scientific article published in March 2017

Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine I

article

Dual-source CT imaging to plan transcatheter aortic valve replacement: accuracy for diagnosis of obstructive coronary artery disease

scientific article

Echocardiographic Features of Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction

scientific article published on 01 December 2019

Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic function in patients with hypertension and diastolic dysfunction: a randomised trial

scientific article published on 01 June 2007

Effect of antihypertensive therapy on ventricular-arterial mechanics, coupling, and efficiency

scientific article published on 10 September 2012

Effect of chronic supraventricular tachycardia on left ventricular function and structure in newborn pigs

scientific article published on 01 December 1992

Effect of losartan and hydrochlorothiazide on exercise tolerance in exertional hypertension and left ventricular diastolic dysfunction

scientific article published on 12 June 2006

Effect of sacubitril/valsartan on recurrent events in the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF).

scientific article published on 12 February 2018

Effect of sacubitril/valsartan versus enalapril on glycaemic control in patients with heart failure and diabetes: a post-hoc analysis from the PARADIGM-HF trial.

scientific article

Effect of the angiotensin-receptor-neprilysin inhibitor LCZ696 compared with enalapril on mode of death in heart failure patients

scientific article published on 28 May 2015

Effects of Sacubitril-Valsartan Versus Valsartan in Women Compared With Men With Heart Failure and Preserved Ejection Fraction: Insights From PARAGON-HF

scientific article published on 17 November 2019

Effects of Sacubitril/Valsartan in the PARADIGM-HF Trial (Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure) According to Background Therapy

scientific article published on September 2016

Effects of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in Patients With HFrEF

scientific article published on 01 February 2019

Effects of Sacubitril/Valsartan on Physical and Social Activity Limitations in Patients With Heart Failure: A Secondary Analysis of the PARADIGM-HF Trial

scientific article published on 01 June 2018

Effects of age on plasma matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs)

scientific article published on September 2007

Effects of chronic tachycardia-induced cardiomyopathy on the beta-adrenergic receptor system ⬇️

scientific article published on 01 October 1992

Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload

scientific article

Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF.

scientific article

Efficacy of Sacubitril/Valsartan Relative to a Prior Decompensation: The PARADIGM-HF Trial

scientific article published on 25 June 2016

Efficacy of sacubitril/valsartan vs. enalapril at lower than target doses in heart failure with reduced ejection fraction: the PARADIGM-HF trial

scientific article published on 10 June 2016

Elevated Wall Tension Leads to Reduced miR-133a in the Thoracic Aorta by Exosome Release

scientific article published on 01 January 2019

Elevation in high-sensitivity troponin T in heart failure and preserved ejection fraction and influence of treatment with the angiotensin receptor neprilysin inhibitor LCZ696.

scientific article published on 02 October 2014

Estimated 5-Year Number Needed to Treat to Prevent Cardiovascular Death or Heart Failure Hospitalization With Angiotensin Receptor-Neprilysin Inhibition vs Standard Therapy for Patients With Heart Failure With Reduced Ejection Fraction: An Analysis

scientific article published on 01 December 2018

Estimating the Long-Term Treatment Benefits of Sacubitril–Valsartan

article

Estrogen-Related Receptor α (ERRα) is required for adaptive increases in PGC-1 isoform expression during electrically stimulated contraction of adult cardiomyocytes in sustained hypoxic conditions.

scientific article published on 25 March 2015

Evaluation of systolic and diastolic properties of hypertensive heart failure using speckle-tracking echocardiography with high volume rates

scientific article

Exploring New Endpoints for Patients With Heart Failure With Preserved Ejection Fraction

scientific article

Fabrication and characterization of bio-engineered cardiac pseudo tissues ⬇️

scientific article published on September 1, 2009

Factors Associated With Noncompletion During the Run-In Period Before Randomization and Influence on the Estimated Benefit of LCZ696 in the PARADIGM-HF Trial

scientific article published on June 2016

Factors Associated With Outcome in Heart Failure With Preserved Ejection Fraction

article

First granted example of novel FDA trial design under Expedited Access Pathway for premarket approval: BeAT-HF

scientific article published on 22 July 2018

Geographic variations in the PARADIGM-HF heart failure trial.

scientific article published on 28 June 2016

Growth differentiation factor-15 is not modified by sacubitril/valsartan and is an independent marker of risk in patients with heart failure and reduced ejection fraction: the PARADIGM-HF trial

scientific article published on 11 September 2018

Growth effects of electrically stimulated contraction on adult feline cardiocytes in primary culture ⬇️

scientific article published on 01 June 1995

HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis.

scientific article

HFpEF: Cardiovascular Abnormalities Not Just Comorbidities ⬇️

scientific article published on 01 November 2012

Health-Related Quality of Life Outcomes in PARADIGM-HF.

scientific article

Health-Related Quality of Life in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Trial

scientific article published on 10 July 2019

Heart Failure in Aortic Stenosis — Improving Diagnosis and Treatment ⬇️

scientific article published on 01 May 2003

Heart Rate and Outcomes in Hospitalized Patients With Heart Failure With Preserved Ejection Fraction

scientific article published in October 2017

Heart failure with preserved ejection fraction in Asia

article

Heart failure with preserved ejection fraction: clinical characteristics of 4133 patients enrolled in the I-PRESERVE trial.

scientific article

Heart failure with preserved ejection fraction: is this diastolic heart failure?**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the Ameri ⬇️

scientific article published on 01 May 2003

Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas

scientific article published on 10 December 2018

Hemodynamic Factors Associated With Acute Decompensated Heart Failure: Part 1—Insights into Pathophysiology ⬇️

scientific article published on February 26, 2011

Hemodynamic factors associated with acute decompensated heart failure: part 2--use in automated detection.

scientific article published on 30 March 2011

Hemodynamic-GUIDEd management of Heart Failure (GUIDE-HF)

scientific article published on 03 May 2019

History of atrial fibrillation as a risk factor in patients with heart failure and preserved ejection fraction

scientific article published on 15 September 2014

How B-Type Natriuretic Peptide (BNP) and Body Weight Changes Vary in Heart Failure With Preserved Ejection Fraction Compared With Reduced Ejection Fraction: Secondary Results of the HABIT (HF Assessment With BNP in the Home) Trial.

scientific article published on 30 September 2015

Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage

scientific article published on 22 April 2015

IGFBP7 (Insulin-Like Growth Factor-Binding Protein-7) and Neprilysin Inhibition in Patients With Heart Failure

scientific article published on 01 October 2018

Impaired left atrial function in heart failure with preserved ejection fraction.

scientific article published on 19 August 2014

Impaired systolic function by strain imaging in heart failure with preserved ejection fraction.

scientific article published on 30 October 2013

Importance of Clinical Worsening of Heart Failure Treated in the Outpatient Setting: Evidence From the Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial (PARADIGM-HF).

scientific article published on 20 April 2016

In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium.

scientific article published on 16 May 2008

In vivo measurements of the contributions of protein synthesis and protein degradation in regulating cardiac pressure overload hypertrophy in the mouse

scientific article published on 19 May 2012

In-hospital resource use and medical costs in the last year of life by mode of death (from the HF-ACTION randomized controlled trial).

scientific article

Incidence, Predictors, and Outcomes Associated With Hypotensive Episodes Among Heart Failure Patients Receiving Sacubitril/Valsartan or Enalapril: The PARADIGM-HF Trial (Prospective Comparison of Angiotensin Receptor Neprilysin Inhibitor With Angiot

scientific article

Income Inequality and Outcomes in Heart Failure: A Global Between-Country Analysis

scientific article published on 06 February 2019

Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium.

scientific article published on 03 May 2016

Increased macrophage-derived SPARC precedes collagen deposition in myocardial fibrosis

scientific article published on 09 March 2018

Increased thin filament activation enhances alternans in human chronic atrial fibrillation

scientific article published on 24 August 2018

Independence of the blood pressure lowering effect and efficacy of the angiotensin receptor neprilysin inhibitor, LCZ696, in patients with heart failure with preserved ejection fraction: an analysis of the PARAMOUNT trial

article

Influence of Ejection Fraction on Outcomes and Efficacy of Sacubitril/Valsartan (LCZ696) in Heart Failure with Reduced Ejection Fraction: The Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Fai

scientific article published on March 2016

Influence of Sacubitril/Valsartan (LCZ696) on 30-Day Readmission After Heart Failure Hospitalization

scientific article published in July 2016

Influenza Vaccination in Patients With Chronic Heart Failure: The PARADIGM-HF Trial

scientific article published on 21 December 2015

Insulin treatment and clinical outcomes in patients with diabetes and heart failure with preserved ejection fraction

scientific article published on 04 July 2019

International geographic variation in event rates in trials of heart failure with preserved and reduced ejection fraction

scientific article published on 18 November 2014

Irbesartan in patients with heart failure and preserved ejection fraction

scientific article

Is Biventricular Fibrosis the Mediator of Late Complications in Tetralogy of Fallot?

scientific article published on 7 December 2015

Lack of relationship between Doppler indices of diastolic function and left ventricular pressure transients in patients with definite diastolic heart failure

scientific article published on 01 September 2004

Lactosylceramide contributes to mitochondrial dysfunction in diabetes

scientific article

Left Ventricular Diastolic Function and Exercise Capacity in Community-Dwelling Adults ≥65 Years of Age Without Heart Failure ⬇️

scientific article published on June 23, 2011

Left Ventricular Length-Force-Shortening Relations Before and After Surgical Correction of Chronic Mitral Regurgitation ⬇️

scientific article published on January 1, 1998

Left ventricular dyssynchrony in patients with heart failure and preserved ejection fraction.

scientific article

Left ventricular end-diastolic volume is normal in patients with heart failure and a normal ejection fraction: a renewed consensus in diastolic heart failure

scientific article published on 20 February 2007

Left ventricular hypertrophy in a canine model of reversible pressure overload

scientific article published on June 1, 1992

Left ventricular layer function in hypertension assessed by myocardial strain rate using novel one-beat real-time three-dimensional speckle tracking echocardiography with high volume rates.

scientific article published on 2 April 2015

Left ventricular structural remodeling in health and disease: with special emphasis on volume, mass, and geometry

scientific article

Left ventricular systolic performance, function, and contractility in patients with diastolic heart failure

scientific article published on 25 April 2005

Left ventricular volume determined echocardiographically by assuming a constant left ventricular epicardial long-axis/short-axis dimension ratio throughout the cardiac cycle

scientific article published on 01 October 1992

Mechanistic relationship between membrane type-1 matrix metalloproteinase and the myocardial response to pressure overload

scientific article published on 06 January 2014

Membrane-associated matrix proteolysis and heart failure.

scientific article

Mitochondrial biogenesis induced by the β2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury

scientific article published on 06 May 2019

Mitral valve replacement with and without chordal preservation in patients with chronic mitral regurgitation. Mechanisms for differences in postoperative ejection performance

scientific article published on December 1, 1992

Mode of death in patients with heart failure and a preserved ejection fraction: results from the Irbesartan in Heart Failure With Preserved Ejection Fraction Study (I-Preserve) trial

scientific article

Multimorbidity in patients with heart failure from 11 Asian regions: A prospective cohort study using the ASIAN-HF registry

scientific article published on 27 March 2018

Myocardial Infarct Expansion and Matrix Metalloproteinase Inhibition

scientific article published on 01 February 2003

Myocardial Na+,K+-ATPase in tachycardia induced cardiomyopathy ⬇️

scientific article published on 01 March 1992

Myocardial fibroblast-matrix interactions and potential therapeutic targets

scientific article published on 26 January 2014

Myocardial mechanisms causing heart failure early after cardiac transplantation

scientific article published on 01 November 2006

Myocardial oxygen consumption and the left ventricular pressure-volume area in normal and hypertrophic canine hearts ⬇️

scientific article published on 01 September 1991

Myocardial remodeling with aortic stenosis and after aortic valve replacement: mechanisms and future prognostic implications.

scientific article published on 16 July 2011

Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titin

scientific article

Myosin cross-bridge dynamics in patients with hypertension and concentric left ventricular remodeling.

scientific article

Nanostructured titanium promotes keratinocyte density ⬇️

scientific article published on February 11, 2011

Natriuretic Peptides as Biomarkers of Treatment Response in Clinical Trials of Heart Failure

scientific article published on 4 March 2018

Natriuretic Peptides, 6-Min Walk Test, and Quality-of-Life Questionnaires as Clinically Meaningful Endpoints in HF Trials.

scientific article published on December 2016

Natural History of Concentric Left Ventricular Geometry in Community-Dwelling Older Adults Without Heart Failure During Seven Years of Follow-Up ⬇️

scientific article published on December 2, 2010

Neuromodulation Device Therapy for Treatment of Hypertensive Heart Disease ⬇️

scientific article published on 09 May 2013

Outcomes and Effect of Treatment According to Etiology in HFrEF: An Analysis of PARADIGM-HF

scientific article published on 08 May 2019

Palliative Care for Advanced Heart Failure in a Department of Veterans Affairs Regional Hospice Program: Patient Selection, a Treatment Protocol, and Clinical Course

scientific article published on 22 May 2017

Patterns of structural and functional remodeling of the left ventricle in chronic heart failure

scientific article published on 24 May 2008

Peter C. Gazes: physician, teacher, scholar

scientific article published in March 2003

Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap.

scientific article published on July 2016

Plasma Biomarkers Reflecting Profibrotic Processes in Heart Failure With a Preserved Ejection Fraction: Data From the Prospective Comparison of ARNI With ARB on Management of Heart Failure With Preserved Ejection Fraction Study

scientific article

Plasma Biomarkers That Reflect Determinants of Matrix Composition Identify the Presence of Left Ventricular Hypertrophy and Diastolic Heart Failure ⬇️

scientific article published on February 24, 2011

Plasma monitoring of the myocardial specific tissue inhibitor of metalloproteinase-4 after alcohol septal ablation in hypertrophic obstructive cardiomyopathy.

scientific article published in March 2005

Post hoc analyses of SHIFT and PARADIGM-HF highlight the importance of chronic Chagas' cardiomyopathy Comment on: "Safety profile and efficacy of ivabradine in heart failure due to Chagas heart disease: a post hoc analysis of the SHIFT trial" by Bocc

article

Prediction of All-Cause Mortality Based on the Direct Measurement of Intrathoracic Impedance

scientific article

Prediction of heart failure hospitalizations based on the direct measurement of intrathoracic impedance

scientific article published on 13 August 2020

Prediction of worsening heart failure events and all-cause mortality using an individualized risk stratification strategy

scientific article published on 28 October 2020

Pressure overload-dependent membrane type 1-matrix metalloproteinase induction: relationship to LV remodeling and fibrosis ⬇️

scientific article published on January 27, 2012

Pressure-overload hypertrophy is unabated in mice devoid of AT1Areceptors ⬇️

scientific article published on 01 March 1998

Prevalence and incidence of intraventricular conduction delays and outcomes in patients with heart failure and reduced ejection fraction: Insights from PARADIGM-HF and ATMOSPHERE

scientific article published on 28 July 2020

Primary culture of avian embryonic heart forming region cells to study the regulation of vertebrate early heart morphogenesis by vitamin A.

scientific article

Prior Pacemaker Implantation and Clinical Outcomes in Patients With Heart Failure and Preserved Ejection Fraction

scientific article published on 10 April 2019

Prognostic Implications of Changes in N-Terminal Pro-B-Type Natriuretic Peptide in Patients With Heart Failure

scientific article published in December 2016

Prognostic Models Derived in PARADIGM-HF and Validated in ATMOSPHERE and the Swedish Heart Failure Registry to Predict Mortality and Morbidity in Chronic Heart Failure

scientific article published on 29 January 2020

Prognostic Relevance of Left Atrial Dysfunction in Heart Failure With Preserved Ejection Fraction.

scientific article published on April 2016

Prognostic Value of Insulin-Like Growth Factor-Binding Protein 7 in Patients with Heart Failure and Preserved Ejection Fraction

scientific article published on 15 June 2016

Prognostic Value of N-Terminal Pro-B-Type Natriuretic Peptide Levels in Heart Failure Patients With and Without Atrial Fibrillation

scientific article

Prognostic value of baseline plasma amino-terminal pro-brain natriuretic peptide and its interactions with irbesartan treatment effects in patients with heart failure and preserved ejection fraction: findings from the I-PRESERVE trial

scientific article published on 29 June 2011

Prognostic value of brain natriuretic peptide vs history of heart failure hospitalization in a large real-world population

scientific article published on 19 September 2020

Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature ⬇️

scientific article published on November 4, 2011

Quantification of protein expression changes in the aging left ventricle of Rattus norvegicus

scientific article

Randomized controlled trial of an implantable continuous hemodynamic monitor in patients with advanced heart failure: the COMPASS-HF study.

scientific article

Randomized, double-blind, placebo-controlled study of sitaxsentan to improve impaired exercise tolerance in patients with heart failure and a preserved ejection fraction

scientific article published on 26 February 2014

Rapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium ⬇️

scientific article published on February 25, 2011

Rate-dependent force, intracellular calcium, and action potential voltage alternans are modulated by sarcomere length and heart failure induced-remodeling of thin filament regulation in human heart failure: A myocyte modeling study.

scientific article published on 24 December 2015

Rationale and design: the VALsartan In Diastolic Dysfunction (VALIDD) Trial: evolving the management of diastolic dysfunction in hypertension

scientific article published on 01 August 2006

Reduced Risk of Hyperkalemia During Treatment of Heart Failure With Mineralocorticoid Receptor Antagonists by Use of Sacubitril/Valsartan Compared With Enalapril: A Secondary Analysis of the PARADIGM-HF Trial

scientific article

Reduced loop diuretic use in patients taking sacubitril/valsartan compared with enalapril: the PARADIGM-HF trial

scientific article published on 11 February 2019

Regional and temporal changes in left ventricular strain and stiffness in a porcine model of myocardial infarction

scientific article published on 13 July 2018

Relation between ventricular and myocyte function with tachycardia-induced cardiomyopathy ⬇️

scientific article published on 01 July 1992

Relation of Lymphangiogenic Factor Vascular Endothelial Growth Factor-D to Elevated Pulmonary Artery Wedge Pressure

scientific article published on 06 June 2019

Relation of N-terminal pro-B-type natriuretic peptide with diastolic function in hypertensive heart disease.

scientific article published on 22 June 2013

Relation of peripheral collagen markers to death and hospitalization in patients with heart failure and preserved ejection fraction: results of the I-PRESERVE collagen substudy

scientific article published on 12 July 2011

Relationship Between the Temporal Profile of Plasma microRNA and Left Ventricular Remodeling in Patients After Myocardial Infarction ⬇️

scientific article published on September 28, 2011

Relationship between heart rate and mortality and morbidity in the irbesartan patients with heart failure and preserved systolic function trial (I-Preserve).

scientific article published on 23 May 2014

Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction

scientific article published on 17 December 2019

Relative Importance of History of Heart Failure Hospitalization and N-Terminal Pro-B-Type Natriuretic Peptide Level as Predictors of Outcomes in Patients With Heart Failure and Preserved Ejection Fraction.

scientific article published on June 2015

Relevance of Changes in Serum Creatinine During a Heart Failure Trial of Decongestive Strategies: Insights From the DOSE Trial

scientific article

Remote Monitoring of Patients with Heart Failure: A White Paper from the Heart Failure Society of America Scientific Statements Committee

article

Renal Effects and Associated Outcomes During Angiotensin-Neprilysin Inhibition in Heart Failure

scientific article published on 5 April 2018

Renal effects of the angiotensin receptor neprilysin inhibitor LCZ696 in patients with heart failure and preserved ejection fraction.

scientific article published on 6 February 2015

Renal sympathetic denervation for blood pressure control: a review of the current evidence and ongoing studies.

scientific article published on 21 March 2014

Renin-angiotensin inhibition in diastolic heart failure and chronic kidney disease

scientific article published on February 2013

Repetitive Acute Hemodynamic Load: Progression From Systolic Decompensation to Cellular/Extracellular Compensation to Diastolic Decompensation

scientific article published on 26 August 2019

Reply: does speckle tracking really improve diagnosis and risk stratification in patients with HF with normal EF?

scientific article published in October 2014

Retinoids control anterior and dorsal properties in the developing forebrain

scientific journal article

Risk Related to Pre-Diabetes Mellitus and Diabetes Mellitus in Heart Failure With Reduced Ejection Fraction: Insights From Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure Trial

scientific article

Risk of stroke in chronic heart failure patients with preserved ejection fraction, but without atrial fibrillation: analysis of the CHARM-Preserved and I-Preserve trials

scientific article

Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure: A Scientific Statement From the American Heart Association

scientific article published on 26 April 2017

Role of High-Dose Beta-Blockers in Patients with Heart Failure with Preserved Ejection Fraction and Elevated Heart Rate

article by Phillip H. Lam et al published 1 August 2018 in American Journal of Medicine

Role of microtubules versus myosin heavy chain isoforms in contractile dysfunction of hypertrophied murine cardiocytes ⬇️

scientific article published on May 15, 2003

STAT3 activation in pressure-overloaded feline myocardium: role for integrins and the tyrosine kinase BMX

scientific article published on 27 June 2008

Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart Failure

scientific article published on 17 November 2019

Safety and Feasibility of a Nocturnal Heart Rate Elevation-Exploration of a Novel Treatment Concept

scientific article published on 17 July 2018

Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization.

scientific article published on 15 April 2015

Severe left ventricular hypertrophy 1 year after transplant predicts mortality in cardiac transplant recipients

scientific article published on 01 February 2007

Sex differences in clinical characteristics and outcomes in elderly patients with heart failure and preserved ejection fraction: the Irbesartan in Heart Failure with Preserved Ejection Fraction (I-PRESERVE) trial

scientific article published on 10 August 2012

Sex-Related Differences in Heart Failure With Preserved Ejection Fraction

scientific article published on 09 December 2019

Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction

scientific article published on 23 February 2014

Should We Test for Diastolic Dysfunction? How and How Often?

scientific article published on 12 June 2019

Specific temporal profile of matrix metalloproteinase release occurs in patients after myocardial infarction: relation to left ventricular remodeling

scientific article published on 21 August 2006

Structural components of cardiomyocyte remodeling: summation

scientific article published on 01 December 2002

Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model

scientific article

Surgical Experience and Long-term Results of Baroreflex Activation Therapy for Heart Failure With Reduced Ejection Fraction.

scientific article published on 2 June 2016

Systolic Blood Pressure and Outcomes in Older Patients with HFpEF and Hypertension

scientific article published on 30 September 2020

Systolic blood pressure, cardiovascular outcomes and efficacy and safety of sacubitril/valsartan (LCZ696) in patients with chronic heart failure and reduced ejection fraction: results from PARADIGM-HF.

scientific article published in February 2017

Tachycardia-induced cardiomyopathy: effects on blood flow and capillary structure ⬇️

scientific article published on July 1, 1991

The Hospitalization Burden and Post-Hospitalization Mortality Risk in Heart Failure With Preserved Ejection Fraction: Results From the I-PRESERVE Trial (Irbesartan in Heart Failure and Preserved Ejection Fraction).

scientific article published on 14 May 2015

The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial

scientific article published on 26 August 2012

The effect of alagebrium chloride (ALT-711), a novel glucose cross-link breaker, in the treatment of elderly patients with diastolic heart failure

scientific article (publication date: April 2005)

The effects of sacubitril/valsartan on coronary outcomes in PARADIGM-HF.

scientific article published on 14 March 2017

The irbesartan in heart failure with preserved systolic function (I-PRESERVE) trial: rationale and design

scientific article

The prevalence and importance of frailty in heart failure with reduced ejection fraction - an analysis of PARADIGM-HF and ATMOSPHERE

scientific article published on 30 April 2020

The prognostic value of troponin T and N-terminal pro B-type natriuretic peptide, alone and in combination, in heart failure patients with and without diabetes

scientific article published on 10 December 2018

The relationship between renal impairment and left ventricular structure, function, and ventricular–arterial interaction in hypertension ⬇️

scientific article published on 01 September 2011

The risk of death associated with proteinuria in heart failure is restricted to patients with an elevated blood urea nitrogen to creatinine ratio

scientific article published on 14 April 2016

The safety of an adenosine A(1)-receptor antagonist, rolofylline, in patients with acute heart failure and renal impairment: findings from PROTECT.

scientific article published in March 2012

Time course of right ventricular pressure-overload induced myocardial fibrosis: relationship to changes in fibroblast postsynthetic procollagen processing ⬇️

scientific article published on August 31, 2012

Transition from chronic compensated to acute decompensated heart failure: pathophysiological insights obtained from continuous monitoring of intracardiac pressures.

scientific article

Type of Atrial Fibrillation and Outcomes in Patients With Heart Failure and Reduced Ejection Fraction

scientific article published in November 2017

Worsening renal function and outcome in heart failure patients with preserved ejection fraction and the impact of angiotensin receptor blocker treatment.

scientific article

β3 Integrin in Cardiac Fibroblast Is Critical for Extracellular Matrix Accumulation during Pressure Overload Hypertrophy in Mouse ⬇️

scientific article published on September 12, 2012

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