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List of works by Ulrich Mahlknecht

Age-related changes in peripheral blood counts in humans

scientific article

Aging and anti-aging: unexpected side effects of everyday medication through sirtuin1 modulation.

scientific article

Azacytidine causes complex DNA methylation responses in myeloid leukemia

scientific article published on September 2008

Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2

scientific article

Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group

scientific article published on 14 September 2009

Chromosomal organization and fluorescence in situ hybridization of the human Sirtuin 6 gene.

scientific article published on February 2006

Chromosomal organization and localization of the human histone deacetylase 9 gene (HDAC9)

scientific article (publication date: 26 April 2002)

Chromosomal organization and localization of the novel class IV human histone deacetylase 11 gene

scientific article

Clinical Epigenetics is now a fully open access journal

scientific article

Cloning and chromosomal characterization of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 gene (PFKFB3, iPFK2)

scientific article (publication date: October 2003)

Cloning and structural characterization of the human histone deacetylase 6 gene

scientific article

Cloning, chromosomal characterization and FISH mapping of the NAD(+)-dependent histone deacetylase gene sirtuin 5 in the mouse

scientific article published on 14 May 2013

Continuous multiparametric monitoring of cell metabolism in response to transient overexpression of the sirtuin deacetylase SIRT3 ⬇️

scientific article published on June 13, 2010

Cooking enhances curcumin anti-cancerogenic activity through pyrolytic formation of "deketene curcumin".

scientific article published on 27 November 2013

Curcumin intake affects miRNA signature in murine melanoma with mmu-miR-205-5p most significantly altered

scientific article (publication date: 2013)

DNMT1 genetic polymorphisms affect breast cancer risk in the central European Caucasian population

scientific article published on 2 May 2013

ESR1 single nucleotide polymorphisms predict breast cancer susceptibility in the central European Caucasian population

scientific article published on 12 April 2013

Epigenetic regulation of cellular adhesion in cancer ⬇️

scientific article published on June 24, 2011

Estrogen Receptor Alpha (ESR1) Single-Nucleotide Polymorphisms (SNPs) Affect Malignant Melanoma Susceptibility and Disease Course

scientific article published on 24 February 2016

Fluorescence in situ hybridization and chromosomal organization of the sirtuin 4 gene (Sirt4) in the mouse

scientific article published on 21 March 2009

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

scientific article published on 13 January 2014

Genomic organization and localization of the NAD-dependent histone deacetylase gene sirtuin 3 (Sirt3) in the mouse

scientific article published on 15 December 2010

HDAC inhibition radiosensitizes human normal tissue cells and reduces DNA Double-Strand Break repair capacity.

scientific article published in January 2010

Histone deacetylase 3, a class I histone deacetylase, suppresses MAPK11-mediated activating transcription factor-2 activation and represses TNF gene expression

scientific article

Histone deacetylase inhibitor treatment downregulates VLA-4 adhesion in hematopoietic stem cells and acute myeloid leukemia blast cells

scientific article published on 11 February 2008

Introductory editorial

scientific article

Involvement of Sirtuins in Life-Span and Aging Related Diseases ⬇️

scientific article published on January 1, 2012

NF-kappaB-dependent control of HIV-1 transcription by the second coding exon of Tat in T cells

scientific article published on 10 December 2007

Nef and TNFalpha are coplayers that favor HIV-1 replication in monocytic cells and primary macrophages

scientific article

On the epigenetics of vascular regulation and disease

scientific article

Pharmacogenomics: questions and concerns

scientific article

Reviewer Acknowledgement 2014

Reviewer acknowledgement 2013

Reviewer acknowledgement 2015.

scientific article published on 14 March 2015

Reviewer acknowledgement 2016.

scientific article published on 17 February 2016

Ribavirin restores ESR1 gene expression and tamoxifen sensitivity in ESR1 negative breast cancer cell lines ⬇️

scientific article published on December 5, 2011

Role of histone deacetylase inhibitors in the treatment of cancer (Review).

scientific article

SIRT3 SNPs validation in 640 individuals, functional analyses and new insights into SIRT3 stability

scientific article published in April 2010

SIRTUIN 1: regulating the regulator

scientific article published on 05 September 2008

Signature of VDR miRNAs and epigenetic modulation of vitamin D signaling in melanoma cell lines

scientific article published on January 1, 2012

Sirtuin1 single nucleotide polymorphism (A2191G) is a diagnostic marker for vibration-induced white finger disease

scientific article

Stem cells and ageing. The potential of stem cells to overcome age-related deteriorations of the body in regenerative medicine

scientific article

Targeting the epigenome: effects of epigenetic treatment strategies on genomic stability in healthy human cells ⬇️

scientific article published on July 27, 2010

The sirtuins in the pathogenesis of cancer

scientific article

The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities

scientific article

Therapeutic platelet transfusion versus routine prophylactic transfusion in patients with haematological malignancies: an open-label, multicentre, randomised study

scientific article

Transcription factor NFκB regulates the expression of the histone deacetylase SIRT1

scientific article published on 19 July 2013

Trastuzumab in Esophagogastric Cancer: HER2-Testing and Treatment Reality outside Clinical Studies in Germany

scientific article

Valproic acid and all-trans retinoic acid: meta-analysis of a palliative treatment regimen in AML and MDS patients

scientific article

Valproic acid sensitizes chronic lymphocytic leukemia cells to apoptosis and restores the balance between pro- and antiapoptotic proteins

scientific article

Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis

scientific article published on 24 August 2006

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