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List of works by Osamu Nakagawa

1,3,9-Triaza-2-oxophenoxazine: An Artificial Nucleobase Forming Highly Stable Self-Base Pairs with Three AgI Ions in a Duplex

scientific article published on 10 April 2019

2'-O,4'-C-Methylene-Bridged Nucleic Acids Stabilize Metal-Mediated Base Pairing in a DNA Duplex

scientific article published on 18 October 2018

A New Nucleic Acid Prodrug Responsive to High Thiol Concentration: Synthesis of 2'-O-Methyldithiomethyl-Modified Oligonucleotides by Post-Synthetic Modification

scientific article published on 01 September 2015

Acid-mediated cleavage of oligonucleotide P3' --> N5' phosphoramidates triggered by sequence-specific triplex formation.

scientific article

Ag(I) ion mediated formation of a C-A mispair by DNA polymerases.

scientific article

Aptamer-Mediated Delivery of Splice-Switching Oligonucleotides to the Nuclei of Cancer Cells ⬇️

scientific article published on June 1, 2012

Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides.

scientific article published on 27 October 2011

Cellular uptake of covalent conjugates of oligonucleotide with membrane-modifying peptide, peptaibol ⬇️

scientific article published on May 15, 2012

Chemical modification of triplex-forming oligonucleotide to promote pyrimidine motif triplex formation at physiological pH ⬇️

scientific article published on January 9, 2012

Conjugation with receptor-targeted histidine-rich peptides enhances the pharmacological effectiveness of antisense oligonucleotides

scientific article published on 19 December 2013

Covalent conjugation of oligonucleotides with cell-targeting ligands.

scientific article published on June 2013

Double-stranded DNA-templated oligonucleotide digestion triggered by triplex formation

scientific article published on 01 November 2007

Effect of Ala replacement with Aib in amphipathic cell-penetrating peptide on oligonucleotide delivery into cells

scientific article published on 30 October 2013

Effective gene silencing activity of prodrug-type 2'-O-methyldithiomethyl siRNA compared with non-prodrug-type 2'-O-methyl siRNA

scientific article published on 08 May 2018

Enzymatic formation of consecutive thymine-HgII-thymine base pairs by DNA polymerases

scientific article published on 09 September 2020

Gene silencing by 2'-O-methyldithiomethyl-modified siRNA, a prodrug-type siRNA responsive to reducing environment

scientific article published on 22 December 2015

Oligonucleotides Containing Phenoxazine Artificial Nucleobases: Triplex-Forming Abilities and Fluorescence Properties

scientific article published on 29 November 2019

Presence of 2',5'-linkages in a homopyrimidine DNA oligonucleotide promotes stable triplex formation under physiological conditions

scientific article published on 01 January 2005

Promotion of stable triplex formation by partial incorporation of 2',5'-phosphodiester linkages into triplex-forming oligonucleotides

scientific article published on 21 April 2005

RGD Conjugated Dendritic Polylysine for Cellular Delivery of Antisense Oligonucleotide.

scientific article published in April 2017

Regulated incorporation of two different metal ions into programmed sites in a duplex by DNA polymerase catalyzed primer extension.

scientific article

Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN.

scientific article

Silver(I)-Ion-Mediated Cytosine-Containing Base Pairs: Metal Ion Specificity for Duplex Stabilization and Susceptibility toward DNA Polymerases

scientific article published on 18 November 2019

Specific fluorescent probe for 8-oxoguanosine

scientific article published on 01 January 2007

Synthesis and binding properties of new selective ligands for the nucleobase opposite the AP site

scientific article published on April 10, 2012

Synthesis and properties of a novel bridged nucleic acid with a P3' --> N5' phosphoramidate linkage, 5'-amino-2',4'-BNA

scientific article published on 01 September 2003

Synthesis and thermal stabilities of oligonucleotides containing 2'-O,4'-C-methylene bridged nucleic acid with a phenoxazine base.

scientific article published on 18 September 2017

Synthesis of novel cationic spermine-conjugated phosphotriester oligonucleotide for improvement of cell membrane permeability.

scientific article published on 27 June 2015

Targeted intracellular delivery of antisense oligonucleotides via conjugation with small-molecule ligands.

scientific article published on July 2010

The chemistry and biology of oligonucleotide conjugates.

scientific article

The spermine-bisaryl conjugate as a potent inducer of B- to Z-DNA transition.

scientific article published on October 2010

[Development of artificial nucleic acids functionalized for damaged gene diagnosis, gene inhibition and delivery system]

scientific article published on 01 January 2014

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