List of works by Celia Perales

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

scientific article

A Two-Level, Intramutant Spectrum Haplotype Profile of Hepatitis C Virus Revealed by Self-Organized Maps

scientific article published on 10 November 2021

A new implication of quasispecies dynamics: Broad virus diversification in absence of external perturbations

scientific article published on 09 March 2020

Amino acid substitutions associated with treatment failure of hepatitis C virus infection

scientific article published on 30 September 2020

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies

scientific article

Antiviral Strategies Based on Lethal Mutagenesis and Error Threshold.

scientific article published on 21 August 2015

Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus

scientific article published on 11 April 2016

Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant

scientific article published on 08 November 2018

Biological effect of Muller's Ratchet: distant capsid site can affect picornavirus protein processing.

scientific article published on 29 April 2009

Broad and Dynamic Diversification of Infectious Hepatitis C Virus in a Cell Culture Environment

scientific article published on 28 February 2020

Cleavage of eIF4G by HIV-1 protease: effects on translation.

scientific article

Clonality and intracellular polyploidy in virus evolution and pathogenesis

scientific article published on 20 July 2015

Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis

scientific article published on 26 September 2018

Correction for Quer at al., High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods

scientific article published on July 2016

Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic Treatment

scientific article (publication date: 2009)

Deep sequencing in the management of hepatitis virus infections.

scientific article published on 28 December 2016

Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure

scientific article published on 16 December 2019

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus

scientific article

Dissimilar Conservation Pattern in Hepatitis C Virus Mutant Spectra, Consensus Sequences, and Data Banks

scientific article published on 27 October 2020

Distance effects during polyprotein processing in the complementation between defective FMDV RNAs

scientific article published on 12 April 2016

Enhancement of DNA, cDNA synthesis and fidelity at high temperatures by a dimeric single-stranded DNA-binding protein

scientific article published on November 2003

Exploration of sequence space as the basis of viral RNA genome segmentation

scientific article

Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis

scientific article published in 2013

Extracellular vesicles: Vehicles of en bloc viral transmission

scientific article published on 27 March 2019

Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus.

scientific article published on 17 March 2017

Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular Relocalization

scientific article

Hepatitis C virus early kinetics and resistance-associated substitution dynamics during antiviral therapy with direct-acting antivirals

scholarly article by Elena Perpiñán published in October 2018

Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivity

scientific article published on 27 February 2015

High HCV subtype heterogeneity in a chronically infected general population revealed by high-resolution hepatitis C virus subtyping

scientific article published on 10 February 2017

High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods

scientific article

Identification of host and viral factors involved in a dissimilar resolution of a hepatitis C virus infection

scientific article published on 20 November 2013

Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus

scientific article published on 13 August 2014

Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus

scientific article published on 19 January 2011

Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants

scientific article published on April 2007

Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment

scientific article published on 8 March 2017

Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.

scientific article

Lethal mutagenesis of foot-and-mouth disease virus involves shifts in sequence space

scientific article published on 14 September 2011

Lethal mutagenesis of viruses

scientific article published on 04 October 2011

MOLECULAR AND EVOLUTIONARY MECHANISMS OF VIRAL EMERGENCE

Microarray-based identification of antigenic variants of foot-and-mouth disease virus: a bioinformatics quality assessment

scientific article

Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.

scientific article

Molecular basis of interferon resistance in hepatitis C virus

scientific article published on 23 June 2014

Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis.

scientific article

Monitoring sequence space as a test for the target of selection in viruses.

scientific article

Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition

scientific article published on 22 April 2015

Mutant spectra in virus behavior

Mutation, Quasispecies, and Lethal Mutagenesis

New hepatitis C virus genotype 1 subtype naturally harbouring resistance-associated mutations to NS5A inhibitors

scientific article published on 14 December 2017

New real-time-PCR method to identify single point mutations in hepatitis C virus.

scientific article

Persistence of foot-and-mouth disease virus in cell culture revisited: implications for contingency in evolution.

scientific article published on January 2008

Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus

scientific article published on 03 September 2018

Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections

scientific article

Quasispecies and Drug Resistance

Quasispecies and Drug Resistance

Quasispecies and virus.

scientific article

Quasispecies as a matter of fact: viruses and beyond.

scientific article

Quasispecies dynamics and clinical significance of HCV antiviral resistance

article

Rare haplotype load as marker for lethal mutagenesis

scientific article published in PLoS ONE

Regulation of HIV-1 env mRNA translation by Rev protein

scientific article published on 01 March 2005

Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications

scientific article

Resistance of high fitness hepatitis C virus to lethal mutagenesis

scholarly article by Isabel Gallego published in October 2018

Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype.

scientific article published on May 2013

SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

scientific article published on 29 March 2022

Synergistic lethal mutagenesis of hepatitis C virus

scientific article published on 30 September 2019

Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach

scientific article

The archaeology of coding RNA

scientific article published on 25 June 2019

The impact of quasispecies dynamics on the use of therapeutics

scientific article published on 16 September 2012

The increasing impact of lethal mutagenesis of viruses

scientific article published on 01 July 2019

Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants.

scientific article

Viral Quasispecies and Lethal Mutagenesis

article published in 2016

Viral Quasispecies: Dynamics, Interactions, and Pathogenesis**Dedicated to Manfred Eigen on the occasion of his 80th birthday, for the insights that his pioneer studies have represented for virology

article

Viral fitness can influence the repertoire of virus variants selected by antibodies.

scientific article published on 7 August 2006

Viral fitness: history and relevance for viral pathogenesis and antiviral interventions

scientific article published on 01 March 2019

Viral genome segmentation can result from a trade-off between genetic content and particle stability

scientific article

Viral quasispecies

scientific article published on 17 October 2019

Viral quasispecies complexity measures.

scientific article

Viral quasispecies evolution

scientific article

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