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List of works by James J. DiNicolantonio

Acarbose, lente carbohydrate, and prebiotics promote metabolic health and longevity by stimulating intestinal production of GLP-1.

scientific article

Acarbose: safe and effective for lowering postprandial hyperglycaemia and improving cardiovascular outcomes

scientific article

Added fructose as a principal driver of non-alcoholic fatty liver disease: a public health crisis

scientific article

Added sugars drive coronary heart disease via insulin resistance and hyperinsulinaemia: a new paradigm

scientific article published on 29 November 2017

Added sugars drive nutrient and energy deficit in obesity: a new paradigm

scientific article

Alcohol and cardiovascular health: the dose makes the poison…or the remedy

scientific article (publication date: March 2014)

Aldosterone antagonists: evidence-based yet underutilized effective heart failure therapy

scientific article published on 18 January 2013

Amlodipine in hypertension: a first-line agent with efficacy for improving blood pressure and patient outcomes

scientific article published on 28 September 2016

An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly

scientific article published on 11 September 2015

Angiotensin receptor blockers for prevention of cardiovascular disease: where does the evidence stand?

scientific article

Antioxidant bilirubin works in multiple ways to reduce risk for obesity and its health complications

article

Association of moderately elevated trimethylamine N-oxide with cardiovascular risk: is TMAO serving as a marker for hepatic insulin resistance

scholarly article by James J DiNicolantonio et al published 2019 in Open heart

Astaxanthin plus berberine: a nutraceutical strategy for replicating the benefits of a metformin/fibrate regimen in metabolic syndrome

scientific article published on 05 August 2019

Atrial fibrillation in the 21st century: a current understanding of risk factors and primary prevention strategies

scientific article published on April 2013

Autophagy-induced degradation of Notch1, achieved through intermittent fasting, may promote beta cell neogenesis: implications for reversal of type 2 diabetes

scientific article published on 22 May 2019

Bioavailable dietary phosphate, a mediator of cardiovascular disease, may be decreased with plant-based diets, phosphate binders, niacin, and avoidance of phosphate additives

scientific article published on 15 December 2013

Boosting endogenous production of vasoprotective hydrogen sulfide via supplementation with taurine and N-acetylcysteine: a novel way to promote cardiovascular health

scientific article published on 22 May 2017

Capsaicin may have important potential for promoting vascular and metabolic health

scientific article published on 17 June 2015

Cardiovascular disease in HIV patients: from bench to bedside and backwards.

scientific article

Carvedilol and spirulina may provide important health protection to smokers and other nicotine addicts: a call for pertinent research.

scientific article published in January 2015

Carvedilol: a third-generation β-blocker should be a first-choice β-blocker ⬇️

scientific article published on January 1, 2012

Challenging the FDA black box warning for high aspirin dose with ticagrelor in patients with diabetes

scientific article published on March 2013

Choosing the best first line oral drug agent in patients with pulmonary hypertension: Evidence from a network meta-analysis

article

Cilostazol--a forgotten antiplatelet agent, but does it even matter?

scientific article published in September 2013

Clinical Outcomes with β-Blockers for Myocardial Infarction: A Meta-analysis of Randomized Trials

scientific article

Clopidogrel is safer than ticagrelor in regard to bleeds: a closer look at the PLATO trial

scientific article published on 29 July 2013

CoQ10 and L-carnitine for statin myalgia? ⬇️

scientific article published on October 1, 2012

Coenzyme Q10 for the treatment of heart failure: a review of the literature

scientific article

Coffee for Cardioprotection and Longevity

scientific article published on 20 February 2018

Comparative safety and efficacy of statins for primary prevention in human immunodeficiency virus-positive patients: a systematic review and meta-analysis

scientific article published on 6 February 2016

Comparing the safety of ticagrelor versus clopidogrel: insights from the FDA reports

scientific article published in February 2013

Copper deficiency may be a leading cause of ischaemic heart disease

Dabigatran or warfarin for the prevention of stroke in atrial fibrillation? A closer look at the RE-LY trial ⬇️

scientific article published on March 22, 2012

Decreased magnesium status may mediate the increased cardiovascular risk associated with calcium supplementation

scientific article published on 22 May 2017

Dietary Glycine Is Rate-Limiting for Glutathione Synthesis and May Have Broad Potential for Health Protection.

scientific article

Dietary Salt Restriction in Heart Failure: Where Is the Evidence?

scientific article published on 22 December 2015

Dietary fats, blood pressure and artery health

scientific article published on 25 June 2019

Dietary sodium restriction: still searching for the grains of truth. The reply

scientific article published in June 2014

Dietary sodium restriction: take it with a grain of salt

scientific article

Disbalance between mortality and non-fatal vascular events in the CHAMPION-PHOENIX trial: the cangrelor efficacy challenge.

scientific article published on 28 November 2013

Does elevated bilirubin aid weight control by preventing development of hypothalamic leptin resistance?

article

Dyspnea and reversibility of antiplatelet agents: ticagrelor, elinogrel, cangrelor, and beyond

scientific article published on 26 October 2013

Effect of aliskiren and valsartan combination versus aliskiren monotherapy on hemostatic biomarkers in hypertensive diabetics: Aliskiren and Valsartan Impact in Diabetics pilot trial

scientific article published in November 2014

Effects of dietary fats on blood lipids: a review of direct comparison trials.

scientific article published on 25 July 2018

Effects of habitual coffee consumption on cardiometabolic disease, cardiovascular health, and all-cause mortality

scientific article published on 17 July 2013

Effects of spirulina on weight loss and blood lipids: a review

scientific article published on 08 March 2020

Efficacy and Safety of Available Protocols for Aspirin Hypersensitivity for Patients Undergoing Percutaneous Coronary Intervention: A Survey and Systematic Review

scientific article

Efficacy of cilostazol on platelet reactivity and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: insights from a meta-analysis of randomised trials

scientific article published on 7 August 2014

Evidence, Not Evangelism, for Dietary Recommendations

scientific article published in February 2018

Evidence-based diuretics: focus on chlorthalidone and indapamide

scientific article

Ezetimibe plus moderate-dose simvastatin after acute coronary syndrome: what are we IMPROVEing on?

scientific article published on 27 February 2015

Fructose-induced inflammation and increased cortisol: A new mechanism for how sugar induces visceral adiposity

scientific article published on 7 December 2017

High dose statin loading prior to percutaneous coronary intervention decreases cardiovascular events: a meta-analysis of randomized controlled trials

scientific article published on 21 December 2013

How calorie-focused thinking about obesity and related diseases may mislead and harm public health. An alternative

scientific article

Hydrochlorothiazide: is it a wise choice? ⬇️

scientific article published on March 19, 2012

Hypertension Due to Toxic White Crystals in the Diet: Should We Blame Salt or Sugar?

scientific article

Hypertension: empirical evidence and implications in 2014

scientific article

Importance of maintaining a low omega-6/omega-3 ratio for reducing inflammation

article published in 2018

Importance of maintaining a low omega-6/omega-3 ratio for reducing platelet aggregation, coagulation and thrombosis.

scientific article

Inactivations, deletions, non-adjudications, and downgrades of clinical endpoints on ticagrelor: serious concerns over the reliability of the PLATO trial

scientific article published on August 2013

Incidence of cardiovascular events and gastrointestinal bleeding in patients receiving clopidogrel with and without proton pump inhibitors: an updated meta-analysis

scientific article

Increase in the intake of refined carbohydrates and sugar may have led to the health decline of the Greenland Eskimos

scientific article published on 26 July 2016

Interleukin-1beta may act on hepatocytes to boost plasma homocysteine - The increased cardiovascular risk associated with elevated homocysteine may be mediated by this cytokine

scientific article published on 14 March 2017

Is Salt a Culprit or an Innocent Bystander in Hypertension? A Hypothesis Challenging the Ancient Paradigm

scientific article

Is concomitant aspirin helping novel oral anticoagulants? Focus on apixaban

scientific article published on 12 September 2014

Is fructose malabsorption a cause of irritable bowel syndrome?

scientific article

Is interleukin-6 the link between low LDL cholesterol and increased non-cardiovascular mortality in the elderly?

scientific article

Is rosiglitazone as safe as BARI 2D and the reanalysis of RECORD imply?

scientific article published on 7 December 2013

It is time to stop counting calories, and time instead to promote dietary changes that substantially and rapidly reduce cardiovascular morbidity and mortality

scientific article

Ivermectin may be a clinically useful anti-inflammatory agent for late-stage COVID-19

scientific article published on 01 September 2020

Ketosis may promote brain macroautophagy by activating Sirt1 and hypoxia-inducible factor-1.

scientific article published on 10 August 2015

L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis

scientific article published on 15 April 2013

Lauric acid-rich medium-chain triglycerides can substitute for other oils in cooking applications and may have limited pathogenicity

scientific article

Letter by DiNicolantonio et al regarding article, "reducing sodium intake to prevent stroke: time for action, not hesitation".

scientific article published on 6 May 2014

Lifestyle Choices Fuel Epidemics of Diabetes and Cardiovascular Disease Among Asian Indians

scientific article published on 12 August 2015

Lifestyle modification in the prevention and treatment of atrial fibrillation

scientific article published on 13 July 2015

Lorcaserin for the treatment of obesity? A closer look at its side effects

scientific article published on 18 October 2014

Lost in follow-up rates in TRACER, ATLAS ACS 2, TRITON and TRA 2P trials: Challenging PLATO mortality rates ⬇️

scientific article published on October 12, 2012

Magnesium for the prevention and treatment of cardiovascular disease.

scientific article published in July 2018

Markedly increased intake of refined carbohydrates and sugar is associated with the rise of coronary heart disease and diabetes among the Alaskan Inuit

scientific article published on 5 December 2017

Mediterranean diet: ω-6 and ω-3 fatty acids and diabetes

scientific article published in September 2017

Meta-Analysis of Carvedilol Versus Beta 1 Selective Beta-Blockers (Atenolol, Bisoprolol, Metoprolol, and Nebivolol) ⬇️

scientific article published on 04 January 2013

Meta-analysis comparing carvedilol versus metoprolol for the prevention of postoperative atrial fibrillation following coronary artery bypass grafting

scientific article

Meta-analysis of randomized controlled trials and adjusted observational results of use of clopidogrel, aspirin, and oral anticoagulants in patients undergoing percutaneous coronary intervention

scientific article published on 12 February 2015

Minimizing Membrane Arachidonic Acid Content as a Strategy for Controlling Cancer: A Review

article

Misrepresentation of vital status follow-up: challenging the integrity of the PLATO trial and the claimed mortality benefit of ticagrelor versus clopidogrel

scientific article published on 07 September 2013

Mortality after clopidogrel in the non-invasive PLATO cohort and TRILOGY ACS trial: another mismatched death paradox

scientific article published on 2 June 2013

Mortality in the TRACER and ATLAS ACS 2 Trials: Two More Reasons to Audit Vital Records in PLATO ⬇️

scientific article published on August 31, 2012

Neuroprotective potential of high-dose biotin

scientific article published on 16 October 2017

Neutralizing the adverse prognosis of coronary artery calcium

scientific article published in August 2013

Not Salt But Sugar As Aetiological In Osteoporosis: A Review

article

Nutraceutical Strategies for Suppressing NLRP3 Inflammasome Activation: Pertinence to the Management of COVID-19 and Beyond

scientific article published on 25 December 2020

Nutraceuticals/Drugs Promoting Mitophagy and Mitochondrial Biogenesis May Combat the Mitochondrial Dysfunction Driving Progression of Dry Age-Related Macular Degeneration

scientific article published in 2022

Nutritional strategies for skeletal and cardiovascular health: hard bones, soft arteries, rather than vice versa

scientific article

Omega-3 fatty acids: a growing ocean of choices

scientific article published on February 2014

Omega-6 vegetable oils as a driver of coronary heart disease: the oxidized linoleic acid hypothesis

P2Y12 antagonists in non-ST-segment elevation acute coronary syndromes: latest evidence and optimal use

scientific article published on July 2015

Pathfinding to an optimal strategy of revascularization in primary coronary intervention in patients with multivessel disease: a network meta-analysis of randomized trials

scientific article published on 16 November 2016

Pentoxifylline for vascular health: a brief review of the literature

scientific article

Percutaneous coronary intervention versus coronary artery bypass graft for stable angina: meta-regression of randomized trials.

scientific article

Perindopril for improving cardiovascular events

scientific article published on 30 August 2014

Perindopril vs Enalapril in Patients with Systolic Heart Failure: Systematic Review and Metaanalysis

scientific article published on January 2014

Postprandial insulin assay as the earliest biomarker for diagnosing pre-diabetes, type 2 diabetes and increased cardiovascular risk

scientific article published on 27 November 2017

Preventing Cardiovascular Disease.

scientific article

Problems with the 2015 Dietary Guidelines for Americans: An Alternative

scientific article published on March 2016

Red Yeast Rice Plus Berberine: Practical Strategy for Promoting Vascular and Metabolic Health.

scientific article published on August 2015

Red yeast rice for dysipidemia

scientific article published on July 2013

Relationships between hyperinsulinaemia, magnesium, vitamin D, thrombosis and COVID-19: rationale for clinical management

scientific article published on 01 September 2020

Should Torsemide Be the Loop Diuretic of Choice in Systolic Heart failure? ⬇️

scientific article published on September 1, 2012

Standardizing portion sizes may not benefit human or environmental health

scientific article published on 16 October 2014

Statin wars: the heavyweight match--atorvastatin versus rosuvastatin for the treatment of atherosclerosis, heart failure, and chronic kidney disease

scientific article published on January 2013

Statins, Ezetimibe, and Proprotein Convertase Subtilisin-Kexin Type 9 Inhibitors to Reduce Low-Density Lipoprotein Cholesterol and Cardiovascular Events

scientific article published on 23 November 2016

Stroke prevention by percutaneous closure of patent foramen ovale: a systematic review and meta-analysis

scientific article published on 21 June 2013

Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis

scientific article published on 13 January 2018

Subcutaneous Versus Transvenous Implantable Defibrillator Therapy: A Meta-Analysis of Case-Control Studies.

scientific article

Sugar addiction: is it real? A narrative review

scientific article

Supplemental N-acetylcysteine and other measures that boost intracellular glutathione can downregulate interleukin-1β signalling: a potential strategy for preventing cardiovascular events?

scientific article published on 28 July 2017

Suppression of NADPH Oxidase Activity May Slow the Expansion of Osteolytic Bone Metastases

scientific article

Systematic oral hydration with water is similar to parenteral hydration for prevention of contrast-induced nephropathy: an updated meta-analysis of randomised clinical data

scientific article

Targeting aspirin resistance with nutraceuticals: a possible strategy for reducing cardiovascular morbidity and mortality

scientific article published on 2 September 2017

The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease

scientific article published on 13 November 2015

The History of the Salt Wars

scientific article published on 22 May 2017

The Importance of Marine Omega-3s for Brain Development and the Prevention and Treatment of Behavior, Mood, and Other Brain Disorders

scientific article published on 04 August 2020

The Interaction Between Statins and Exercise: Mechanisms and Strategies to Counter the Musculoskeletal Side Effects of This Combination Therapy

scientific article

The Microvascular and Macrovascular Benefits of Fibrates in Diabetes and the Metabolic Syndrome: A review.

scientific article published in November 2017

The cardiometabolic benefits of glycine: Is glycine an 'antidote' to dietary fructose?

scientific article published on 28 May 2014

The cardiometabolic consequences of replacing saturated fats with carbohydrates or Ω-6 polyunsaturated fats: Do the dietary guidelines have it wrong?

scientific article

The effects of ezetimibe/simvastatin versus simvastatin monotherapy on platelet and inflammatory biomarkers in patients with metabolic syndrome

scientific article

The health benefits of vitamin K

scientific article

The importance of a balanced ω-6 to ω-3 ratio in the prevention and management of obesity

scientific article published on 20 September 2016

The molecular biology and pathophysiology of vascular calcification

scientific article

The protection conferred by chelation therapy in post-MI diabetics might be replicated by high-dose zinc supplementation

scientific article published on 31 January 2015

The questionable benefits of exchanging saturated fat with polyunsaturated fat.

scientific article published on 26 February 2014

The wrong white crystals: not salt but sugar as aetiological in hypertension and cardiometabolic disease

scientific article

Thiamine and cardiovascular disease: A literature review

scientific article published on 19 January 2018

Thiamine supplementation for the treatment of heart failure: a review of the literature

scientific article published on July 2013

Thrombotic complications of COVID-19 may reflect an upregulation of endothelial tissue factor expression that is contingent on activation of endosomal NADPH oxidase

scientific article published on 01 June 2020

Treatment of Depression in Patients with Concomitant Cardiac Disease

scientific article published on 9 November 2015

Vitamin D and atherosclerosis

scientific article

β-Alanine and orotate as supplements for cardiac protection

scientific article

β-Blockers in hypertension, diabetes, heart failure and acute myocardial infarction: a review of the literature

scientific article

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