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List of works by William J Pearce

A Novel Technique for Visualizing and Analyzing the Cerebral Vasculature in Rodents

scientific article published on 15 May 2018

A path well travelled may lead to better stroke recovery

scientific article published on 30 March 2018

Acute intranasal osteopontin treatment in male rats following TBI increases the number of activated microglia but does not alter lesion characteristics

scientific article published on 20 March 2019

Advancing age alters rapid and spontaneous refilling of caffeine-sensitive calcium stores in sympathetic superior cervical ganglion cells.

scientific article

Advancing age alters the expression of the ryanodine receptor 3 isoform in adult rat superior cervical ganglia.

scientific article

Age-dependent changes in Ca2+ homeostasis in peripheral neurones: implications for changes in function

scientific article

Ca2+-activated K+ channel-associated phosphatase and kinase activities during development

scientific article published on 11 February 2005

Cerebrovascular effects of ischemic preconditioning: endothelial survivin joins the fray.

scientific article published on 30 March 2007

Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys.

scientific article published on 20 September 2017

Chronic cerebrovascular dysfunction after traumatic brain injury

scientific article

Chronic hypoxia alters fetal cerebrovascular responses to endothelin-1.

scientific article

Chronic hypoxia alters the function of NOS nerves in cerebral arteries of near-term fetal and adult sheep.

scientific article published on 25 October 2002

Chronic hypoxia and VEGF differentially modulate abundance and organization of myosin heavy chain isoforms in fetal and adult ovine arteries ⬇️

scientific article published on September 19, 2012

Chronic hypoxia attenuates the vasodilator efficacy of protein kinase G in fetal and adult ovine cerebral arteries.

scientific article published on 26 May 2017

Chronic hypoxia modulates endothelium-dependent vasorelaxation through multiple independent mechanisms in ovine cranial arteries.

scientific article published on January 2006

Chronic hypoxia modulates relations among calcium, myosin light chain phosphorylation, and force differently in fetal and adult ovine basilar arteries.

scientific article published in July 2005

Contribution of increased VEGF receptors to hypoxic changes in fetal ovine carotid artery contractile proteins.

scientific article published on 16 January 2013

Contributions of VEGF to age-dependent transmural gradients in contractile protein expression in ovine carotid arteries ⬇️

scientific article published on June 8, 2011

Core and Penumbral Nitric Oxide Synthase Activity During Cerebral Ischemia and Reperfusion ⬇️

scientific article published on May 1, 1998

Developmental Changes in the Calcium Sensitivity of Rabbit Cranial Arteries ⬇️

scientific article published on January 1, 1998

Developmental acceleration of bradykinin-dependent relaxation by prenatal chronic hypoxia impedes normal development after birth

scientific article published on 04 December 2015

Differential cerebrovascular and metabolic responses in specific neural systems elicited from the centromedian-parafascicular complex

scientific article published on July 1, 1992

Effect of maternal undernutrition on vascular expression of micro and messenger RNA in newborn and aging offspring

scientific journal article

Effects of chronic hypoxia on soluble guanylate cyclase activity in fetal and adult ovine cerebral arteries

scientific article published on 30 April 2009

Effects of nitric oxide and GABA interaction within ventrolateral medulla on cardiovascular responses during static muscle contraction ⬇️

scientific article published on December 20, 2001

Effects of opioid receptor activation on cardiovascular responses and extracellular monoamines within the rostral ventrolateral medulla during static contraction of skeletal muscle ⬇️

scientific article published on December 1, 2001

Endothelial glucocorticoid receptor promoter methylation according to dexamethasone sensitivity.

scientific article published on 4 August 2015

Endothelium-derived relaxing factor and cyclic GMP-dependent vasorelaxation in human chorionic plate arteries ⬇️

scientific article published on June 1, 1994

Epigenetics: an expanding new piece of the stroke puzzle

scientific article

Excess maternal glucocorticoids in response to in utero undernutrition inhibit offspring angiogenesis.

scientific article published on 23 October 2013

Expression of several cytoskeletal proteins in ovine cerebral arteries: developmental and functional considerations.

scientific article

Fetal Cerebrovascular Maturation: Effects of Hypoxia

scientific article published on 20 June 2018

Fetal cerebral oxygenation: the homeostatic role of vascular adaptations to hypoxic stress.

scientific article

Fetal cerebrovascular acclimatization responses to high-altitude, long-term hypoxia: a model for prenatal programming of adult disease?

scientific article

For myosin light chain phosphatase, a very small subunit can make very big differences in the heart

scientific article published on 23 March 2018

Gestational Hypoxia and Developmental Plasticity

scientific article published on 01 July 2018

High Altitude, Hypoxic-Induced Modulation of Noradrenergic-Mediated Responses in Fetal and Adult Cerebral Arteries ⬇️

scientific article published on March 1, 1998

Hypoxic depression of PKG-mediated inhibition of serotonergic contraction in ovine carotid arteries ⬇️

scientific article published on February 27, 2013

Hypoxic regulation of the fetal cerebral circulation.

scientific article

Imatinib attenuates cerebrovascular injury and phenotypic transformation after intracerebral hemorrhage in rats.

scientific article published on 5 October 2016

In cerebrovascular circadian rhythms, EETs keep the beat. Focus on "Rhythmic expression of cytochrome P450 epoxygenases CYP4x1 and CYP2c11 in the rat brain and vasculature".

scientific article published on October 2014

In vivo imaging demonstrates a time-line for new vessel formation in islet transplantation

scientific article

Inhibition of stress fiber formation preserves blood-brain barrier after intracerebral hemorrhage in mice

scientific article published on 18 November 2016

Long-term effects of maternal undernutrition on offspring carotid artery remodeling: role of miR-29c

scientific article published on 26 May 2015

Long-term hypoxia uncouples Ca and eNOS in bradykinin-mediated pulmonary arterial relaxation

scientific article published on 07 March 2018

Long-term maternal hypoxia: the role of extracellular Ca2+ entry during serotonin-mediated contractility in fetal ovine pulmonary arteries.

scientific article

Male and female mice exhibit divergent responses of the cortical vasculature to traumatic brain injury

scientific article published on 5 March 2018

Maternal food restriction modulates cerebrovascular structure and contractility in adult rat offspring: effects of metyrapone.

scientific article published on 29 January 2014

Maturation Alters the Contractile Role of Calcium in Ovine Basilar Arteries ⬇️

scientific article published on August 1, 1998

Maturation and differentiation of the fetal vasculature.

scientific article published on September 2013

Maturational modulation of endothelium-dependent vasodilatation in ovine cerebral arteries.

scientific article published on 9 September 2004

Mechanisms of platelet-induced angiospastic reactions: potentiation of calcium sensitivity

scientific article published on 01 July 1997

MicroRNAs in brain development and cerebrovascular pathophysiology

scientific article published on 06 March 2019

Modulation of BK channel calcium affinity by differential phosphorylation in developing ovine basilar artery myocytes

scientific article published on 01 August 2006

Modulation of pressor response to muscle contraction via monoamines following AMPA-receptor blockade in the ventrolateral medulla ⬇️

scientific article published on December 1, 2001

Myogenic contractility is more dependent on myofilament calcium sensitization in term fetal than adult ovine cerebral arteries

scientific article published on 23 March 2007

PDGFR-β modulates vascular smooth muscle cell phenotype via IRF-9/SIRT-1/NF-κB pathway in subarachnoid hemorrhage rats

scientific article published on 26 February 2018

Platelet-Derived Growth Factor Receptor-β Regulates Vascular Smooth Muscle Cell Phenotypic Transformation and Neuroinflammation After Intracerebral Hemorrhage in Mice

scientific article published on 2 December 2015

Postnatal maturation attenuates pressure-evoked myogenic tone and stretch-induced increases in Ca2+ in rat cerebral arteries

scientific article published on 06 June 2007

Prenatal metyrapone treatment modulates neonatal cerebrovascular structure, function, and vulnerability to mild hypoxic-ischemic injury

scientific article published on 02 October 2019

Preservation of serotonin-mediated contractility in adult sheep pulmonary arteries following long-term high-altitude hypoxia

scientific article

Recanalization, reperfusion, and recirculation in stroke.

scientific article

Recombinant Osteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/Integrin-Linked Kinase/Rac-1 Pathway After Subarachnoid Hemorrhage in Rats

scientific article published on 22 March 2016

Regulation of baseline Ca2+ sensitivity in permeabilized uterine arteries: effect of pregnancy.

scientific article published on 24 February 2006

Role of BCL2-associated athanogene 1 in differential sensitivity of human endothelial cells to glucocorticoids.

scientific article published on 14 March 2013

Role of prostanoids in the regulation of cerebral blood flow during normoxia and hypoxia in the fetal sheep.

scientific article published on 20 September 2006

Role of the sympathetic autonomic nervous system in hypoxic remodeling of the fetal cerebral vasculature

scientific article

Simultaneous glutamate and γ-aminobutyric acid release within ventrolateral medulla during skeletal muscle contraction in intact and barodenervated rats ⬇️

scientific article published on December 27, 2001

The fetal cerebral circulation: three decades of exploration by the LLU Center for Perinatal Biology

scientific article published on January 2014

Traumatic brain injury results in acute rarefication of the vascular network.

scientific article

Up-regulation of Wnt/β-catenin expression is accompanied with vascular repair after traumatic brain injury

scientific article published in January 2017

VEGF receptors mediate hypoxic remodeling of adult ovine carotid arteries.

scientific article

Vascular smooth muscle cells direct extracellular dysregulation in aortic stiffening of hypertensive rats

scientific article published on 30 March 2018

Vasotrophic regulation of age-dependent hypoxic cerebrovascular remodeling

scientific article published on 01 September 2013

Vitamin D status and metabolism in an ovine pregnancy model: effect of long-term, high-altitude hypoxia.

scientific article published on 03 May 2016

miR-29c induction contributes to downregulation of vascular extracellular matrix proteins by glucocorticoids

scientific article published on 27 May 2015

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