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List of works by George M. Shaw

4E10-resistant variants in a human immunodeficiency virus type 1 subtype C-infected individual with an anti-membrane-proximal external region-neutralizing antibody response

scientific article

A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251.

scientific article

A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays

scientific article published on 8 December 2009

A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity

scientific article

Acute HIV-1 Infection

scientific article published on May 19, 2011

Adaptation of HIV-1 to its human host.

scientific article

African origin of the malaria parasite Plasmodium vivax

scientific article

Amplification of a complete simian immunodeficiency virus genome from fecal RNA of a wild chimpanzee

scientific article

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

scientific article

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

scientific article

Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals

scientific article

Ancestral and consensus envelope immunogens for HIV-1 subtype C.

scientific article

Antibody neutralization and escape by HIV-1

scientific article (publication date: 20 March 2003)

Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors

scientific article published on 24 June 2009

Antigenic conservation and immunogenicity of the HIV coreceptor binding site

scientific article

Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins

scientific article published on 13 November 2006

Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein

scientific article published on January 2005

Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1

scientific article published on 30 January 2013

Assessment of Antiretroviral Therapy by Plasma Viral Load Testing

article

Association of strong virus-specific CD4 T cell responses with efficient natural control of primary HIV-1 infection

scientific article published in March 2004

Autologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys

scientific article (publication date: June 2010)

B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

scientific article

Biologically diverse molecular variants within a single HIV-1 isolate

scientific article published in Nature

Bis-anthracycline antibiotics inhibit human immunodeficiency virus type 1 transcription

scientific article published on May 2004

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

scientific article published on 26 August 2007

Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection

scientific article

Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region

scientific article published on 19 August 2009

Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection

scholarly article published by Pamela J. Bjorkman in 2018

Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance

scientific article

CD154-CD40-induced reactivation of latent HIV-1 infection

scientific article published on September 15, 2003

Chimpanzee reservoirs of pandemic and nonpandemic HIV-1

scientific article

Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis

scientific article published on 14 August 2013

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

scientific article

Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: in vitro expression and immune responses in DNA-vaccinated mice

scientific article published in September 2003

Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques

scientific article

Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein

scientific article

Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design

scientific article published on 24 April 2013

Complete genome analysis of one of the earliest SIVcpzPtt strains from Gabon (SIVcpzGAB2).

scientific article published on December 2004

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

scientific article

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

scientific article published on 14 September 2017

Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

scientific article published on 24 May 2016

Corrigendum to “Modeling sequence evolution in acute HIV-1 infection” [J. Theor. Biol. 261 (2009) 341–360]

article

Corrigendum to: Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes [Virology 475 (2015) 37–45]

article

Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy

scientific article (publication date: 10 May 2011)

Cyclosporin A

Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing

scientific article published on 6 February 2008

Derivation and Characterization of Pathogenic Transmitted/Founder Molecular Clones from Simian Immunodeficiency Virus SIVsmE660 and SIVmac251 following Mucosal Infection

scientific article published on 13 July 2016

Determinants of human immunodeficiency virus type 1 baseline susceptibility to the fusion inhibitors enfuvirtide and T-649 reside outside the peptide interaction site

scientific article published on July 2004

Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response

scientific article published in November 2004

Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency

scientific article

Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors

scientific article published on 4 April 2007

Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages

scientific article

Dynamics of HIV-1 recombination in its natural target cells

scholarly article

Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape

scientific article

Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir

scientific article

Effective treatment of SIVcpz-induced immunodeficiency in a captive western chimpanzee

scientific article

Elucidation of hepatitis C virus transmission and early diversification by single genome sequencing

scientific article

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

scientific article

Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

scientific article published on 31 May 2016

Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission

scientific article published in March 2004

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies

scientific article published on 29 August 2012

Epitopes for broad and potent neutralizing antibody responses during chronic infection with human immunodeficiency virus type 1.

scientific article published on 17 November 2009

Erratum: Antibody neutralization and escape by HIV-1

scientific article published in Nature

Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways

scientific article published on 18 September 2009

Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection

scientific article

Evidence for potent autologous neutralizing antibody titers and compact envelopes in early infection with subtype C human immunodeficiency virus type 1

scientific article

Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection

scientific article

Foci of endemic simian immunodeficiency virus infection in wild-living eastern chimpanzees (Pan troglodytes schweinfurthii).

scientific article

Generation of infectious molecular clones of simian immunodeficiency virus from fecal consensus sequences of wild chimpanzees

scientific article published on 9 May 2007

Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages

scientific article published on 21 December 2011

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

scientific article published on June 2009

Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies

scientific article

Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria.

scientific article

HIV Transmission

scientific article published on November 1, 2012

HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

scientific article

HIV-1 Vpu Mediates HLA-C Downregulation

scientific article published on May 2016

HIV-Host Interactions: Implications for Vaccine Design

scientific article

HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies

scientific article

Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication

scientific article published on 4 November 2014

Heterogeneity in neutralization sensitivities of viruses comprising the simian immunodeficiency virus SIVsmE660 isolate and vaccine challenge stock

scientific article published on 6 March 2013

High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.

scientific article

High prevalence of simian immunodeficiency virus infection in a community of savanna chimpanzees

scientific article

High throughput drug screening for human immunodeficiency virus type 1 reactivating compounds

scientific article published on April 2007

High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination

scientific article published on 18 March 2009

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

scientific article

Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection

scientific article

Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma

scientific article

Human immunodeficiency viruses: SIV infection in wild gorillas

scientific article

Identification, molecular cloning, and analysis of full-length hepatitis C virus transmitted/founder genotypes 1, 3, and 4

scientific article

Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys

scientific article published on May 2011

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

scientific article

In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth

scientific article

Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

scientific article

Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design

scientific article published on 28 May 2008

Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes

scientific article published on 22 November 2014

Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1

scientific article

Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses

scientific article published on 18 January 2017

Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia

scientific article

Innate immune responses in acute HIV-1 infection: protective or pathogenic?

article

Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants

scientific article

Low Multiplicity of HIV-1 Infection and No Vaccine Enhancement in VAX003 Injection Drug Users

scientific article

Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys

scientific article

Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1.

scientific article published on 04 May 2009

Macrophage HIV-1 infection and the gastrointestinal tract reservoir

scientific article

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

scientific article

Modeling sequence evolution in acute HIV-1 infection

scientific article published on 04 August 2009

Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees

scientific article

Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones

scientific article published on November 2012

Molecular mechanisms of HIV type 1 prophylaxis failure revealed by single-genome sequencing

scientific article published on 09 September 2013

Mucosal simian immunodeficiency virus transmission in African green monkeys: susceptibility to infection is proportional to target cell availability at mucosal sites

scientific article published on 8 February 2012

Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers

scientific article (publication date: September 2016)

Multigenomic Delineation of Plasmodium Species of the Laverania Subgenus Infecting Wild-Living Chimpanzees and Gorillas

scientific article

Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection

scientific article

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

scientific article published on 21 April 2015

Neutralizing IgG at the portal of infection mediates protection against vaginal simian/human immunodeficiency virus challenge

scientific article published on 21 August 2013

New simian immunodeficiency virus infecting De Brazza's monkeys (Cercopithecus neglectus): evidence for a cercopithecus monkey virus clade

scientific article

Noninvasive detection of Simian immunodeficiency virus infection in a wild-living L'Hoest's monkey (Cercopithecus Ihoesti).

scientific article published in December 2003

Origin and biology of simian immunodeficiency virus in wild-living western gorillas

scientific article published on 10 December 2008

Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing

scientific article published on 29 December 2010

Origin of AIDS: contaminated polio vaccine theory refuted.

scientific article

Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes

scientific article

Origin of the human malaria parasite Plasmodium falciparum in gorillas

scientific article

Origin of the human malaria parasite Plasmodium falciparum in gorillas.

scientific article

Pathogen-Associated Molecular Pattern Recognition of Hepatitis C Virus Transmitted/Founder Variants by RIG-I Is Dependent on U-Core Length

scientific article

Phenotypic and immunologic comparison of clade B transmitted/founder and chronic HIV-1 envelope glycoproteins

scientific article

Phenotypic properties of transmitted founder HIV-1

scientific article

Plasmodium falciparum-like parasites infecting wild apes in southern Cameroon do not represent a recurrent source of human malaria

scientific article

Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection

scientific article

Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals

scientific article

Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants

scientific article published on 10 January 2013

Primary infection by a human immunodeficiency virus with atypical coreceptor tropism

scientific article published on 10 August 2011

Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells

scientific article

Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

scientific article published on 24 September 2008

Quantifying the diversification of hepatitis C virus (HCV) during primary infection: estimates of the in vivo mutation rate

scientific article

Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections

scientific article

Relative resistance of HIV-1 founder viruses to control by interferon-alpha

scientific article published on 03 December 2013

Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness

scientific article published on 09 January 2017

Risk to human health from a plethora of simian immunodeficiency viruses in primate bushmeat

scientific article

SIVcpz in wild chimpanzees

scientific article

Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth

scientific article

Selection Pressure on HIV-1 Envelope by Broadly Neutralizing Antibodies to the Conserved CD4-Binding Site

scientific article published on March 14, 2012

Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins

scientific article

Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI.

scientific article

Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys) from the Taï Forest, Côte d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2.

scientific article

Simian immunodeficiency virus infection in wild-caught chimpanzees from cameroon

scientific article published on January 2005

Single genome amplification and direct amplicon sequencing of Plasmodium spp. DNA from ape fecal specimens

scientific article published on September 2010

Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification

scientific article

Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity

scientific article published on 9 December 2015

Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses

scientific article

Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site

scientific article (publication date: May 2009)

Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence

article published in the Proceedings of the National Academy of Sciences of the United States of America

Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability

scientific article

Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.

scientific article

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

scientific article published on June 2009

Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection

scientific article

Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

scientific article

Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients

scientific article

Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5.

scientific article published on 26 December 2012

Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7

scientific article

Transmitted/founder hepatitis C viruses induce cell-type- and genotype-specific differences in innate signaling within the liver

scientific article

Treatment response in acute/early infection versus advanced AIDS: equivalent first and second phases of HIV RNA decline

scientific article published on May 2008

Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1.

scientific article published on 14 March 2007

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

scholarly article by Matthias G Pauthner et al published 15 January 2019 in Immunity

Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge

scientific article published on 29 April 2009

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape

scientific article

Wide variation in the multiplicity of HIV-1 infection among injection drug users

scientific article

Widely varying SIV prevalence rates in naturally infected primate species from Cameroon

scientific article

Wild bonobos host geographically restricted malaria parasites including a putative new Laverania species

scientific article published on 21 November 2017