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List of works by Tom Perls

: Measuring Functional Decline in Population Aging in a Changing World and an Evolving Biology

scientific article published on 01 June 2004

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A family longevity selection score: ranking sibships by their longevity, size, and availability for study.

scientific article

A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4.

scientific article

A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples

scientific article

A meta-analysis of genome-wide association studies identifies multiple longevity genes

scientific article published on 14 August 2019

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A novel healthy blood pressure phenotype in the Long Life Family Study.

scientific article

Achieving and maintaining cognitive vitality with aging

scientific article

Acute Care Costs of the Oldest Old ⬇️

scientific article published on July 15, 1997

Acute care costs of the oldest old: they cost less, their care intensity is less, and they go to nonteaching hospitals

scientific article published on April 1996

Age and Sex Distributions of Age-Related Biomarker Values in Healthy Older Adults from the Long Life Family Study.

scientific article published on 26 October 2016

Age validation in the long life family study through a linkage to early-life census records

scientific article published on 23 May 2013

An efficient technique for Bayesian modeling of family data using the BUGS software

scientific article

An oral health study of centenarians and children of centenarians

scientific article

Analysis of Cutaneous Delayed-Type Hypersensitivity Reaction and T Cell Proliferative Response in Elderly Nursing Home Patients: An Approach to Identifying Immunodeficient Patients

article

Anti-aging teleconference: what is anti-aging medicine?

scientific article published on January 2003

Apolipoprotein E and familial longevity

scientific article published on 5 October 2012

Are Members of Long-Lived Families Healthier Than Their Equally Long-Lived Peers? Evidence From the Long Life Family Study

scientific article published on 5 March 2015

Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology

scientific article published on 13 June 2016

Association of longer telomeres with better health in centenarians

scientific article

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Assortative Mating by Ethnicity in Longevous Families

scientific article

BRCA1 gene sequence variation in centenarians

scientific article

Bayesian Polynomial Regression Models to Fit Multiple Genetic Models for Quantitative Traits ⬇️

scientific article published on March 2015

Biomarker signatures of aging

scientific article

Burden of disease variants in participants of the Long Life Family Study

scientific article

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

scientific article published on 29 September 2017

COVID-19 deaths in long term care facilities - a critical piece of the pandemic puzzle

scientific article published on 05 June 2020

Cancer Diagnosis, Polygenic Risk, and Longevity-Associated Variants

scientific article published on 22 September 2020

Cancer in the oldest old.

scientific article

Cardiovascular Advantages Among the Offspring of Centenarians

scientific article published on 01 May 2003

Cardiovascular disease delay in centenarian offspring

scientific article published in April 2004

Cardiovascular disease delay in centenarian offspring: role of heat shock proteins

scientific article

Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions

scientific article published on June 1999

Centenarian offspring: start healthier and stay healthier

scientific article

Centenarians and the genetics of longevity.

scientific article

Centenarians prove the compression of morbidity hypothesis, but what about the rest of us who are genetically less fortunate?

scientific article published on 01 November 1997

Centenarians who avoid dementia

scientific article published in October 2004

Centenarians: the older you get, the healthier you have been

scientific article published in The Lancet

Characteristics of 32 supercentenarians

scientific article

Clustering by genetic ancestry using genome-wide SNP data

scientific article

Cognitive functional status of age-confirmed centenarians in a population-based study

scientific article published in May 2001

Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly

scientific article

Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity

scientific article published on 5 July 2016

Dementia-free centenarians

scientific article

Detection of Significant Groups in Hierarchical Clustering by Resampling

scientific article

Disease mongering of age-associated declines in testosterone and growth hormone levels.

scientific article

Disentangling the roles of disability and morbidity in survival to exceptional old age.

scientific article

Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits

scientific article

Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies.

scientific article

Exceptional memory performance in the Long Life Family Study

scientific article

Extended maternal age at birth of last child and women's longevity in the Long Life Family Study

scientific article

Familial Risk for Exceptional Longevity ⬇️

scientific article published on 7 October 2015

Families Enriched for Exceptional Longevity also have Increased Health-Span: Findings from the Long Life Family Study

scientific article published on 30 September 2013

First Autopsy Study of an Okinawan Centenarian: Absence of Many Age-Related Diseases

scientific article published on 01 November 2004

Four Genome-Wide Association Studies Identify New Extreme Longevity Variants

scientific article published on 15 March 2017

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

scientific article

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis

scientific article

Genetic and environmental influences on exceptional longevity and the AGE nomogram

scientific article

Genetic signatures of exceptional longevity in humans

scientific article (publication date: 2012)

Genetics of exceptional longevity

article

Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.

scientific article published on January 2013

Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index

scientific article published on 10 March 2015

Genome-wide association studies and the genetic dissection of complex traits

scientific article published on August 2009

Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).

scientific article published on 04 December 2013

Genome-wide association study of personality traits in the long life family study

scientific article published on 8 May 2013

Growth hormone and anabolic steroids: athletes are the tip of the iceberg

scientific article published in September 2009

Guest Editorial: Genetic and Phenotypic Markers Among Centenarians

scientific article published on 01 February 2001

Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan

scientific article

Health and function of participants in the Long Life Family Study: A comparison with other cohorts

scientific article

Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span

scientific article published on 4 January 2012

Heritability of and mortality prediction with a longevity phenotype: the healthy aging index

scientific article published on 02 August 2013

Heritability of telomere length in a study of long-lived families

scientific article

Heterogeneity of the Predictive Polygenic Risk Scores for Coronary Heart Disease Age-at-Onset in Three Different Coronary Heart Disease Family-Based Ascertainments

scientific article published in June 2021

Higher Respiratory Infection Rates on an Alzheimer's Special Care Unit and Successful Intervention

scientific article

Hope drives antiaging hype

scientific article

Human longevity and common variations in the LMNA gene: a meta-analysis

scientific article

ICC-dementia (International Centenarian Consortium - dementia): an international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups

scientific article

Imputation of missing genotypes: an empirical evaluation of IMPUTE.

scientific article

Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of "Aging," "Life Span," and "Longevity".

scientific article published on 26 March 2015

Is there an antiaging medicine?

scientific article

Learning Bayesian Networks from Correlated Data

scientific article

Life-long sustained mortality advantage of siblings of centenarians

scientific article

Limitations and risks of meta-analyses of longevity studies

scientific article

Longevity Genes: From Primitive Organisms to Humans

article

Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring

scientific article

Male Centenarians: How and Why Are They Different from Their Female Counterparts?

scientific article published on 6 June 2017

Manual and Automated Procedures for Compiling a Very Large Sample of Centenarian Pedigrees

scientific article published on 27 September 2018

Meta‐analysis of genetic variants associated with human exceptional longevity

scientific article

Middle-aged mothers live longer

scientific article published in Nature

Morbidity profiles of centenarians: survivors, delayers, and escapers

scientific article published on March 2003

New developments in the illegal provision of growth hormone for "anti-aging" and bodybuilding

scientific article

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel loci and pathways significantly associated with longevity

scientific article published on 25 February 2016

Personality factors in the Long Life Family Study

scientific article

Personality traits of centenarians' offspring

scientific article

Prediction models that include genetic data

scientific article published on February 2010

Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society

scientific article published on 29 September 2015

Provision or distribution of growth hormone for "antiaging": clinical and legal issues

scientific article

Purpose in Life Among Centenarian Offspring.

scientific article published on 7 March 2018

RETRACTED: Genetic signatures of exceptional longevity in humans

retracted scientific article

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans

scientific article

Reduced apolipoprotein epsilon 4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals

scientific article published in August 1994

Reply to Comment on COVID-19 deaths in long term care facilities - a critical piece of the puzzle

scientific article published on 24 August 2020

Retraction

scientific article published on 01 July 2011

Scanning the beta-globin gene for mutations in large populations by denaturing capillary and gel electrophoresis

scientific article published in June 2005

Science fact and the SENS agenda. What can we reasonably expect from ageing research?

scientific article

Sex Differences in Genetic Associations With Longevity

Siblings of centenarians live longer

scientific article published in The Lancet

Successful aging and its subtypes in centenarians: The Chinese experience

scientific article published in May 2023

SuperAger Initiative: unlocking the genetic potential of exceptional longevity

scientific article published on 18 May 2023

Survival of parents and siblings of supercentenarians

scientific article published on September 2007

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

Telomere length is longer in women with late maternal age.

scientific article published on 5 December 2016

The Reappearance of Procaine Hydrochloride (Gerovital H3) for Antiaging ⬇️

scientific article published on June 1, 2013

The Survival of Spouses Marrying Into Longevity-Enriched Families.

scientific article published on 18 August 2016

The different paths to 100.

scientific article

The different paths to age one hundred

scientific article

The evolution of menopause and human life span

scientific article

The genetics of aging

scientific article

The genetics of aging-- implications for pharmacogenomics

scientific article

The genetics of exceptional human longevity

scientific article

The genetics of exceptional human longevity

article

The genetics of extreme longevity: lessons from the new England centenarian study

scientific article

The hype and the reality--part I.

scientific article published on June 2004

The oldest old.

scientific article published on January 1995

The relationship between age, gender and cognitive performance in the very old: the effect of selective survival

scientific article published on 01 November 1993

Typologies of extreme longevity myths

scientific article

Understanding the determinants of exceptional longevity

scientific article

Unraveling the mystery of cognitive changes in old age: correlation of neuropsychological evaluation with neuropathological findings in the extreme old.

scientific article published in March 1998

Validity of reported age and centenarian prevalence in New England

article

What does it take to live to 100?

scientific article

Whole genome sequences of a male and female supercentenarian, ages greater than 114 years

scientific article published on January 2011

Within- and between-species study of extreme longevity--comments, commonalities, and goals

scientific article published on 14 March 2012

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