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List of works by Torbjörn C. Bäckström

3Beta-hydroxysteroids and pregnenolone sulfate inhibit recombinant rat GABA(A) receptor through different channel property

scientific article published on 12 December 2006

3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone

scientific article published in September 2004

A comparison of the pharmacological properties of recombinant human and rat alpha(1)beta(2)gamma(2L) GABA(A) receptors in Xenopus oocytes

scientific article published on 21 April 2008

Action by and sensitivity to neuroactive steroids in menstrual cycle related CNS disorders

scientific article

Acute intermittent porphyria symptoms during the menstrual cycle.

scientific article published in July 2015

Adverse mood effects during postmenopausal hormone treatment in relation to personality traits

scientific article published in August 2006

Agonist function of the recombinant alpha 4 beta 3 delta GABAA receptor is dependent on the human and rat variants of the alpha 4-subunit

scientific article published on 12 March 2010

Allopregnanolone and mood disorders

scientific article

Allopregnanolone and pregnanolone are produced by the human corpus luteum

scientific article published in July 2005

Allopregnanolone concentration and mood--a bimodal association in postmenopausal women treated with oral progesterone

scientific article (publication date: August 2006)

Allopregnanolone decrease with symptom improvement during placebo and gonadotropin-releasing hormone agonist treatment in women with severe premenstrual syndrome

scientific article published in May 2007

Allopregnanolone has no effect on startle response and prepulse inhibition of startle response in patients with premenstrual dysphoric disorder or healthy controls

scientific article published on 4 March 2009

Allopregnanolone impairs episodic memory in healthy women

scientific article

Allopregnanolone induces a diurnally dependent hyperphagic effect and alters feeding latency and duration in male Wistar rats

scientific article published on 17 April 2013

Allopregnanolone inhibits learning in the Morris water maze

scientific article published in May 2002

Allopregnanolone involvement in feeding regulation, overeating and obesity

scientific article

Allopregnanolone preferentially induces energy-rich food intake in male Wistar rats

scientific article

Allopregnanolone promotes success in food competition in subordinate male rats

scientific article published on 15 June 2013

Allopregnanolone serum concentrations and diurnal cortisol secretion in women with premenstrual dysphoric disorder

scientific article published on 18 January 2013

Allopregnanolone serum concentrations and neurosteroid sensitivity during withdrawal from postmenopausal hormone therapy

scientific article published in October 2007

Allopregnanolone, a GABAA receptor agonist, decreases gonadotropin levels in women. A preliminary study

scientific article

Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone).

scientific article published in August 2003

Altered sensitivity to alcohol in the late luteal phase among patients with premenstrual dysphoric disorder

scientific article published in July 2004

Anaesthetic effects of pregnanolone in combination with allopregnanolone, thiopental, hexobarbital and flurazepam: an EEG study in the rat.

scientific article published in May 1999

Androstenedione production by malignant epithelial ovarian tumors

scientific article published in October 1986

Anisomycin and verapamil influence the action of progesterone on regulation of term human myometrial contractile activity

scientific article published on 01 September 1997

Antitachyphylactic effects of progesterone and oxytocin on term human myometrial contractile activity in vitro

scientific article published on 01 October 1993

Apoptosis, proliferation, and hormone receptors in endometrial carcinoma: results depending on methods of analysis.

scientific article published in January 2003

Apoptosis, proliferation, and sex hormone receptors in superficial parts of human endometrium at the end of the secretory phase

scientific article published on 01 May 1999

Apoptosis, proliferation, and sex steroid receptors in postmenopausal endometrium before and during HRT.

scientific article published in October 2004

Binding of [3H]paroxetine to serotonin uptake sites and of [3H]lysergic acid diethylamide to 5-HT2A receptors in platelets from women with premenstrual dysphoric disorder during gonadotropin releasing hormone treatment

scientific article published in August 2001

Brief but Chronic Increase in Allopregnanolone Cause Accelerated AD Pathology Differently in Two Mouse Models ⬇️

scientific article published on January 1, 2013

Changes in functioning of mesolimbic incentive processing circuits during the premenstrual phase

scientific article

Chronic Allopregnanolone Treatment Accelerates Alzheimer's Disease Development in AβPPSwePSEN1ΔE9 Mice ⬇️

scientific article published on January 1, 2012

Citalopram increases pregnanolone sensitivity in patients with premenstrual syndrome: an open trial

scientific article published in January 1998

Cognitive function in association with sex hormones in postmenopausal women

scientific article published on 11 September 2012

Comparison between pre- and postovulatory distributions of oestradiol and progesterone in the brain of the PMSG-treated rat.

scientific article

Compartmentalization of human chorionic gonadotrophin sensitivity and luteinizing hormone receptor mRNA in different subtypes of the human corpus luteum.

scientific article published on May 1997

Continuous progesterone exposure associated with high contraction frequency in human term myometrial strips

scientific article published on 01 March 1994

Decrease in serum concentration of 5 alpha-pregnane-3,20-dione prior to spontaneous labor

scientific article published on 01 January 1988

Direct intracellular injections for studying human myometrial gap junctions prior to labor

scientific article published on 01 February 1994

EGF/TGF-alpha and progesterone in urine of ovarian cancer patients

scientific article published on 01 September 1994

Effects in vitro of progesterone and two 5α‐reduced progestins, 5α‐pregnane‐3,20‐dione and 5α‐pregnane‐3α‐ol‐20‐one, on contracting human myometrium at term ⬇️

scientific article published on January 1, 1992

Effects of GABA active steroids in the female brain with focus on the premenstrual dysphoric disorder

scientific article

Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor density

scientific article

Effects of allopregnanolone on sedation in men, and in women on oral contraceptives

scientific article published on 30 April 2007

Effects of continuous combined conjugated estrogen/medroxyprogesterone acetate and 17beta-estadiol/norethisterone acetate on lipids and lipoproteins

scientific article

Effects of estradiol and interaction with progesterone or oxytocin on term human myometrial contractile activity

scientific article published on 01 January 1996

Effects of progesterone and oxytocin on intracellular elemental composition of term human myometrium in vitro

scientific article published on September 1996

Endocrine response to pregnanolone

scientific article published in October 1999

Endocrinological aspects of the premenstrual syndrome

scientific article

Erratum to: Women with PTSD have a changed sensitivity to GABA-A receptor active substances

scientific article published on 25 November 2014

Estradiol and testosterone in specific regions of the human female brain in different endocrine states

scientific article published on 01 December 1995

Estradiol and the addition of progesterone increase the sensitivity to a neurosteroid in postmenopausal women

scientific article published in January 2005

Estrogen and progesterone receptors in ovarian epithelial tumors

scientific article

Evaluation of gonadotropin-releasing hormone agonist treatment for prevention of menstrual-related attacks in acute porphyria

scientific article published in January 2010

GABA(A) receptor changes in acute allopregnanolone tolerance

scientific article published on 2 March 2006

GABA-A receptor modulating steroids in acute and chronic stress; relevance for cognition and dementia?

scientific article published on 20 December 2019

GABAA Receptor-Modulating Steroids in Relation to Women's Behavioral Health

scientific article

GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo

scientific article

GR3027 antagonizes GABAA receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy

scientific article published on 2 July 2015

GR3027 reversal of neurosteroid-induced, GABA-A receptor-mediated inhibition of human brain function: an allopregnanolone challenge study

scientific article published on 28 February 2018

Gap junction density in human myometrium at term revealed by an anti-peptide antibody and laser scanning confocal microscopy.

scientific article published on January 1993

High progesterone is related to effective human labor. Study of serum progesterone and 5alpha-pregnane-3,20-dione in normal and abnormal deliveries

scientific article published on 01 May 1997

Human chorionic gonadotropin, follicle-stimulating hormone, and luteinizing hormone in patients with epithelial ovarian carcinoma

scientific article

In vitro effect of Hepes buffer on maintaining the number of gap junction plaques in human myometrium at term

scientific article published on January 1995

Increase of estrogen dose deteriorates mood during progestin phase in sequential hormonal therapy

scientific article published in May 2003

Increased neurosteroid sensitivity--an explanation to symptoms associated with chronic work related stress in women?

scientific article

Influence of postmenopausal hormone replacement therapy on platelet serotonin uptake site and serotonin 2A receptor binding

scientific article

Interaction between allopregnanolone and pregnenolone sulfate in modulating GABA-mediated synaptic currents in neurons from the rat medial preoptic nucleus

scientific article

Interaction of sex steroids and oxytocin on term human myometrial contractile activity in vitro

scientific article published on 01 August 1994

Intratumoral effects of medroxy-progesterone on proliferation, apoptosis, and sex steroid receptors in endometrioid endometrial adenocarcinoma

scientific article published in January 2004

Isoallopregnanolone antagonize allopregnanolone-induced effects on saccadic eye velocity and self-reported sedation in humans

scientific article

Isoallopregnanolone reduces tic-like behaviours in the D1CT-7 mouse model of Tourette syndrome

scientific article published on 07 June 2019

Isoallopregnanolone; an antagonist to the anaesthetic effect of allopregnanolone in male rats

scientific article

Isolation and culture of ovarian tumour cells, cytological and cell survival evaluation

scientific article published on 01 November 1999

Ki-67 immunostaining and DNA flow cytometry as prognostic factors in epithelial ovarian cancers

scientific article

Lack of influence of menstrual cycle and premenstrual syndrome diagnosis on pregnanolone pharmacokinetics

scientific article published in April 1999

Long-term continuous allopregnanolone elevation causes memory decline and hippocampus shrinkage, in female wild-type B6 mice

scientific article published on 21 October 2015

Long-term effects of two different continuous combined regimens of hormone replacement therapy on well-being

scientific article published in June 2004

Low serum allopregnanolone is associated with symptoms of depression in late pregnancy

scientific article published on 26 April 2014

Lower levels of prepulse inhibition of startle response in pregnant women compared to postpartum women

scientific article published on 26 November 2007

Luteal-Phase Estradiol Relates to Symptom Severity in Patients with Premenstrual Syndrome1 ⬇️

scientific article published on June 1, 1998

Menstrual cycle-related changes in amygdala morphology are associated with changes in stress sensitivity

scientific article published on 8 December 2011

Midbrain-medulla oblongata and hippocampus are the critical brain parts involving allopregnanolone and pregnanolone induced anaesthesia

scientific article published in October 1999

Morphometric analysis of gap junction density in human myometrium at term

scientific article published on 01 May 1994

Myometrial steroid concentration and oxytocin receptor density in parturient women at term

scientific article published on 01 June 1996

Negative mood changes during hormone replacement therapy: a comparison between two progestogens

scientific article published in December 2000

Negative mood induction by progestagen is related to a history of premenstrual syndrome

scientific article published on 01 October 1999

Neural mechanisms underlying changes in stress-sensitivity across the menstrual cycle

scientific article published in January 2010

Neuroactive steroid effects on cognitive functions with a focus on the serotonin and GABA systems

scientific article

Neuroactive steroids and central nervous system disorders.

scientific article

Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte

scientific article published on 27 July 2006

Neurosteroids 3beta, 20 (R/S)-pregnandiols decrease offset rate of the GABA-site activation at the recombinant GABA A receptor

scientific article published on 29 February 2008

No difference in responsiveness to a low dose of alcohol between healthy women and men.

scientific article published in July 2004

Ovarian hormone effects on 5-hydroxytryptamine(2A) and 5-hydroxytryptamine(2C) receptor mRNA expression in the ventral hippocampus and frontal cortex of female rats

scientific article (publication date: 22 February 2002)

Ovarian steroid hormones. Effects on mood, behaviour and brain excitability

scientific article

Pathogenesis in menstrual cycle-linked CNS disorders

scientific article (publication date: December 2003)

Patients with premenstrual dysphoric disorder have increased startle response across both cycle phases and lower levels of prepulse inhibition during the late luteal phase of the menstrual cycle

scientific article published on 17 October 2007

Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects

scientific article published in February 1998

Patients with premenstrual syndrome have decreased saccadic eye velocity compared to control subjects

scientific article published in October 1998

Patients with premenstrual syndrome have reduced sensitivity to midazolam compared to control subjects

scientific article published in December 1997

Patterns of injury and reported violence depending on relationship to assailant in female Swedish sexual assault victims

scientific article published on 14 May 2012

Peritoneal fluid and HCG influence on steroid production from ovarian tumor tissue, in vitro

scientific article published on 01 September 1994

Persistence of tolerance to the anaesthetic effect of allopregnanolone in male rats

scientific article published on 4 July 2008

Pharmacokinetic and behavioral effects of allopregnanolone in healthy women

scientific article published on 21 September 2005

Pharmacokinetics of progesterone and its metabolites allopregnanolone and pregnanolone after oral administration of low-dose progesterone

scientific article

Physical symptoms in premenstrual syndrome are related to plasma progesterone and desoxycorticosterone

scientific article published in June 2000

Plasma 20 alpha-OH-progesterone in women with malignant epithelial 'non-endocrine' ovarian tumors

scientific article published in January 1985

Plasma level of estradiol in patients with ovarian malignant tumors

scientific article published in July 1988

Plasma progesterone and androstenedione in relation to changes in tumor volume and recurrence in women with ovarian carcinoma

scientific article published in January 1986

Post-mortem stability of progesterone in rat brain

scientific article

Postural control in women with premenstrual symptoms during oral contraceptive treatment

scientific article published on 26 November 2010

Potency of lipid and protein formulation of 5 alpha-pregnanolone at induction of anaesthesia and the corresponding regional brain distribution

scientific article published in May 1995

Prefrontal activity during response inhibition decreases over time in the postpartum period

scientific article published on 10 December 2012

Pregnenolone sulphate and pregnenolone do not interact with 5 beta-pregnanolone- and hexobarbitone-induced anaesthesia in the rat.

scientific article

Premenstrual syndrome

scientific article published on 01 January 1982

Premenstrual syndrome, Comparison between different methods to diagnose cyclicity using daily symptom ratings ⬇️

scientific article published on 01 May 1998

Premenstrual syndrome, neuroactive steroids and the brain

scientific article

Premenstrual syndrome--psychiatric or gynaecological disorder?

scientific article

Progesterone Increases cAMP Release and Accumulation in Isolated Term Human Myometrium ⬇️

scientific article published on 01 January 1998

Progesterone and estradiol stimulate release of epidermal growth factor/transforming growth factor alpha by ovarian tumours in vitro

scientific article published on 01 November 1994

Progesterone as a possible tumor marker for "nonendocrine" ovarian malignant tumors

scientific article published in August 1983

Progesterone concentrations in maternal and fetal serum are lower during functional dystocia than in normal labor.

scientific article

Progesterone distribution in the brain of the PMSG treated female rat.

scientific article published in November 1984

Progesterone effects during sequential hormone replacement therapy

scientific article published in May 2003

Progesterone selectively increases amygdala reactivity in women

scientific article published on 19 June 2007

Progesterone withdrawal effects in the open field test can be predicted by elevated plus maze performance

scientific article published on 4 May 2006

Progesterone, 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-5alpha-pregnane-20-one in specific regions of the human female brain in different endocrine states

scientific article published in August 1997

Progesterone, oestradiol and oxytocin and their in vitro effect on maintaining the number of gap junction plaques in human myometrium at term

scientific article published on August 1996

Progestogen addition during oestrogen replacement therapy--effects on vasomotor symptoms and mood

scientific article

Quantitative immunoconfocal analysis of human myometrial gap junction connexin43 in relation to steroid hormone concentrations at term labour

scientific article

Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: a pilot study

scientific article published in January 1997

Regional distribution of progesterone and 5 alpha-pregnane-3,20-dione in rat brain during progesterone-induced "anesthesia".

scientific article published in January 1990

Relationship between allopregnanolone and negative mood in postmenopausal women taking sequential hormone replacement therapy with vaginal progesterone

scientific article published in February 2005

Relationship between ca 125 and progesterone production in women with ovarian carcinoma

article

Relationship between symptom severity and hormone changes in women with premenstrual syndrome

scientific article published on January 1989

Repeated allopregnanolone exposure induces weight gain in schedule fed rats on high fat diet

scientific article

Results of primary radiation treatment of endometrial carcinoma. 20 years' experience of an unselected material from the north of Sweden

scientific article published on 01 January 1989

Sensitivity to a neurosteroid is increased during addition of progestagen to postmenopausal hormone replacement therapy

scientific article published in June 2001

Serotonin 5-HT(1A) receptor mRNA expression in dorsal hippocampus and raphe nuclei after gonadal hormone manipulation in female rats

scientific article published in August 2001

Serum concentrations of progesterone and 5 alpha-pregnane-3,20-dione during labor and early post partum

scientific article published on 01 January 1990

Serum dehydroepiandrosterone sulfate in Alzheimer's disease and in multi-infarct dementia

scientific article published in October 1991

Sex steroid hormones and receptors in relation to S-phase fraction and ploidy level in endometrial carcinoma

scientific article published on 01 May 1995

Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABAA modulators

scientific article (publication date: September 2009)

Sex steroid receptors and human parturition

scientific article published in June 1997

Sex steroids in human brain tumors and breast cancer

scientific article

Sexuality and androgens in women with cyclical mood changes and pre-menstrual syndrome

scientific article

Significance of initial plasma steroid concentrations in the prognosis of 'nonendocrine' malignant ovarian tumors

scientific article published on 01 January 1989

Spontaneous anovulation causing disappearance of cyclical symptoms in women with the premenstrual syndrome

scientific article published on August 1991

Steroid hormone effects on intercellular communication between term pregnant human myometrial cells before labor

scientific article published on 01 August 1996

Steroid production in different parts of malignant and benign ovarian tumors in vitro

scientific article published on 01 May 1993

Steroid receptors and hormones in relation to cell proliferation and apoptosis in poorly differentiated epithelial ovarian tumors

scientific article published in July 2001

Structural and functional studies of gap junctions in human myometrium

scientific article published on 01 March 1993

Studies of pharmacokinetic and pharmacodynamic properties of isoallopregnanolone in healthy women

scientific article

Testosterone, SHBG and albumin in patients with ovarian carcinoma

scientific article published in January 1986

The author's reply: Blood allopregnanolone levels in women with polycystic ovary syndrome

scientific article published on 8 April 2016

The effect of a low dose of alcohol on allopregnanolone serum concentrations across the menstrual cycle in women with severe premenstrual syndrome and controls

scientific article published in October 2005

The effect of the neuroactive steroid 5beta-pregnane-3beta, 20(R)-diol on the time course of GABA evoked currents is different to that of pregnenolone sulphate

scientific article published on 10 January 2009

The impact of different doses of medroxyprogesterone acetate on mood symptoms in sequential hormonal therapy

scientific article published in February 2002

The influence of social subordinate housing on the withdrawal effects from progesterone and estradiol in male rats ⬇️

scientific article published on February 24, 2012

The interaction between ethanol and pregnanolone at induction of anaesthesia investigated with a threshold method in male rats

scientific article

The pattern of estradiol and progesterone differs in serum and tissue of benign and malignant ovarian tumors.

scientific article published in September 2002

The role of hormones and hormonal treatments in premenstrual syndrome.

scientific article

Tolerance to allopregnanolone with focus on the GABA-A receptor

scientific article

Treatment of premenstrual dysphoric disorder with the GABAA receptor modulating steroid antagonist Sepranolone (UC1010)-A randomized controlled trial

scientific article

Treatment of premenstrual syndrome by spironolactone: a double-blind, placebo-controlled study

scientific article published on 01 November 1995

Treatment of premenstrual syndrome with gonadotropin-releasing hormone agonist in a low dose regimen

scientific article published in October 1999

Unexpected stimulatory effect of progesterone on human myometrial contractile activity in vitro

scientific article published on 01 July 1993

Well-being at onset of hormone replacement therapy: comparison between two continuous combined regimens

scientific article published in March 2004

Withdrawal effects from progesterone and estradiol relate to individual risk-taking and explorative behavior in female rats

scientific article

Women with PTSD have a changed sensitivity to GABA-A receptor active substances

scientific article

Women with acute intermittent porphyria have a defect in 5α-steroid production during the menstrual cycle

scientific article published in November 2012

Women with polycystic ovary syndrome have elevated serum concentrations of and altered GABA(A) receptor sensitivity to allopregnanolone

scientific article

Women with premenstrual dysphoric disorder have altered sensitivity to allopregnanolone over the menstrual cycle compared to controls-a pilot study

scientific article published on 10 March 2016

X-ray microanalysis of myometrium in parturient women at term

scientific article published on 01 January 1996

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