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List of works by W. Martin Kast

A NOD/SCID tumor model for human ovarian cancer that allows tracking of tumor progression through the biomarker Sp17.

scientific article

A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression

scientific article

A major role for the minor capsid protein of human papillomavirus type 16 in immune escape

scientific article

A novel murine model for evaluating bovine papillomavirus prophylactics/therapeutics for equine sarcoid-like tumours

scientific article

A novel series of conferences tackling the hurdles confronting the translation of novel cancer immunotherapies.

scientific article published on 5 November 2012

A paradigm shift in therapeutic vaccination of cancer patients: the need to apply therapeutic vaccination strategies in the preventive setting

scientific article published on April 2008

A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia.

scientific article published on 12 July 2007

A rapid isolation procedure for dendritic cells from mouse spleen by centrifugal elutriation

scientific article published on 01 October 1992

AKAP-4: a novel cancer testis antigen for multiple myeloma

scientific article published on 01 February 2008

Abolition of specific immune response defect by immunization with dendritic cells

scientific article published in Nature

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

scientific article published on 19 August 2002

Activation or frustration of anti-tumor responses by T-cell-based immune modulation ⬇️

scientific article published on October 1, 1997

Advances in immunotherapy for prostate cancer

scientific article

Advances in immunotherapy of multiple myeloma: from the discovery of tumor-associated antigens to clinical trials.

scientific article published on May 2007

Advances in immunotherapyfor prostate cancer

scholarly article by Mary A. Markiewicz & W. Martin Kast published 2003 in Advances in Cancer Research

Advances in prophylactic cancer vaccine research

scientific article

Allograft tolerance induction in adult mice associated with functional deletion of specific CTL precursors

scientific article published on 01 November 1989

Alternative splicing in the mouse H-2Kd gene is not necessary for the classical Kd antigen function

scientific article published on 01 January 1986

An HLA class I peptide-binding assay based on competition for binding to class I molecules on intact human B cells. Identification of conserved HIV-1 polymerase peptides binding to HLA-A*0301

scientific article published on 01 December 1995

Androgen ablation augments prostate cancer vaccine immunogenicity only when applied after immunization

scientific article published on May 2009

Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro.

scientific article

Annexin A2 in Virus Infection

scientific article published on 05 December 2018

Antitumor efficacy of Venezuelan equine encephalitis virus replicon particles encoding mutated HPV16 E6 and E7 genes

scientific article published in January 2004

Autoantibodies to p53 in ovarian cancer patients and healthy women: a comparison between whole p53 protein and 18-mer peptides for screening purposes

scientific article published on 01 June 1997

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

scientific article published on 01 December 1995

Bovine papillomavirus DNA can be detected in keratinocytes of equine sarcoid tumors.

scientific article

CD4+ T cell matters in tumor immunity.

scientific article

Cancer immunotherapy: avoiding the road to perdition

scientific article

Cancer testes antigens in breast cancer: biological role, regulation, and therapeutic applicability.

scientific article published on October 2012

Cancer testis antigen Sperm Protein 17 as a new target for triple negative breast cancer immunotherapy

scientific article

Cancer testis antigen vaccination affords long-term protection in a murine model of ovarian cancer.

scientific article

Cancer testis antigen, ropporin, is a potential target for multiple myeloma immunotherapy

scientific article published in July 2011

Cancer testis antigens: novel biomarkers and targetable proteins for ovarian cancer.

scientific article published on April 2011

Cellular immunity against DNA tumour viruses: possibilities for peptide-based vaccines and immune escape.

scientific article published on August 1995

Cellular immunity against human papillomavirus associated cervical cancer

Cellular immunity and immunotherapy against deoxyribonucleic acid virus-induced tumors

scientific article published on April 1, 1998

Cervical cancer vaccines: recent advances in HPV research

scientific article

Cervico-vaginal self-collection in HIV-infected and uninfected women from Tapajós region, Amazon, Brazil: High acceptability, hrHPV diversity and risk factors

article

Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model

scientific article published in February 1998

Comparison of human papillomavirus type 16 L1 chimeric virus-like particles versus L1/L2 chimeric virus-like particles in tumor prevention.

scientific article published on January 2002

Competition inhibition of cytotoxic T-lymphocyte (CTL) lysis, a more sensitive method to identify candidate CTL epitopes than induction of antibody-detected MHC class I stabilization.

scientific article

Cure of glioma: a space not yet occupied for the lesion

scientific article published on 01 January 2004

Current therapeutic vaccination and immunotherapy strategies for HPV-related diseases.

scientific article published on 02 February 2016

Dendritic Cells as Carriers for a Cytotoxic T-Lymphocyte Epitope-Based Peptide Vaccine in Protection Against a Human Papillomavirus Type 16-Induced Tumor

Detailed motifs for peptide binding to HLA-A*0201 derived from large random sets of peptides using a cellular binding assay

scientific article published on 01 May 1995

Detection of T helper responses, but not of human papillomavirus-specific cytotoxic T lymphocyte responses, after peptide vaccination of patients with cervical carcinoma.

scientific article

Different requirements for the regulation of transplantation tolerance induction for allogeneic versus xenogeneic major histocompatibility complex antigens

scientific article published on 01 November 1990

Differential effect of transporter Tap 2 gene introduction into RMA-S cells on viral antigen processing

scientific article published on December 1993

Differential uptake and cross-presentation of human papillomavirus virus-like particles by dendritic cells and Langerhans cells

scientific article

Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro.

scientific article published on August 1990

Disease-stage variance in functional CD4(+) T-cell responses against novel pan-human leukocyte antigen-D region presented human papillomavirus-16 E7 epitopes.

scientific article published in May 2004

Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer.

scientific article published on 24 February 2009

Effects of TGF-beta on the immune system: implications for cancer immunotherapy.

scientific article

Efficient MHC class I-peptide binding is required but does not ensure MHC class I-restricted immunogenicity

scientific article published on 01 December 1994

Efficient tumor eradication by adoptively transferred cytotoxic T-cell clones in allogeneic hosts

scientific article published on 01 May 1996

Emerging strategies in tumor vaccines.

scientific article

Enhanced tumour growth after DNA vaccination against human papilloma virus E7 oncoprotein: evidence for tumour-induced immune deviation

scientific article published on June 2003

Eradication of established HPV 16-expressing tumors by a single administration of a vaccine composed of a liposome-encapsulated CTL-T helper fusion peptide in a water-in-oil emulsion

scientific article published on 18 April 2006

Establishment of an HLA-A*0201 human papillomavirus type 16 tumor model to determine the efficacy of vaccination strategies in HLA-A*0201 transgenic mice.

scientific article published on October 2002

Expression of LIGHT/TNFSF14 combined with vaccination against human papillomavirus Type 16 E7 induces significant tumor regression

scientific article

Forced LIGHT expression in prostate tumors overcomes Treg mediated immunosuppression and synergizes with a prostate tumor therapeutic vaccine by recruiting effector T lymphocytes

scientific article

Functional analysis of HPV-like particle-activated Langerhans cells in vitro.

scientific article

Functional and ultrastructural aspects of antigen processing by dendritic cells

scientific article published on January 1995

Gamma-radiation upregulates MHC class I/II and ICAM-I molecules in multiple myeloma cell lines and primary tumors.

scientific article published on March 2006

HPV protein/peptide vaccines: from animal models to clinical trials

scientific article

HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation.

scientific article published on March 2003

Head and neck squamous cell cancer and the human papillomavirus: summary of a National Cancer Institute State of the Science Meeting, November 9-10, 2008, Washington, D.C.

scientific article published in November 2009

Herpes simplex virus downregulation of secretory leukocyte protease inhibitor enhances human papillomavirus type 16 infection.

scientific article published on 10 November 2015

Heterologous boosting increases immunogenicity of chimeric papillomavirus virus-like particle vaccines

scientific article published on July 2003

Heterologous papillomavirus virus-like particles and human papillomavirus virus-like particle immune complexes activate human Langerhans cells.

scientific article

Heterotetrameric annexin A2/S100A10 (A2t) is essential for oncogenic human papillomavirus trafficking and capsid disassembly, and protects virions from lysosomal degradation

scientific article published in Scientific Reports

Human Immunodeficiency Virus Immune Cell Receptors, Coreceptors, and Cofactors: Implications for Prevention and Treatment.

scientific article published on July 2016

Human papillomavirus L1L2-E7 virus-like particles partially mature human dendritic cells and elicit E7-specific T-helper responses from patients with cervical intraepithelial neoplasia or cervical cancer in vitro.

scientific article published in July 2005

Human papillomavirus can escape immune recognition through Langerhans cell phosphoinositide 3-kinase activation

scientific article

Human papillomavirus infection in head and neck cancer: the role of the secretory leukocyte protease inhibitor

scientific article

Human papillomavirus virus-like particles do not activate Langerhans cells: a possible immune escape mechanism used by human papillomaviruses

scientific article

Human papillomavirus-exposed Langerhans cells are activated by stabilized Poly-I:C.

scientific article

Identification of AKAP-4 as a new cancer/testis antigen for detection and immunotherapy of prostate cancer

scientific article published on 25 April 2011

Identification of HLA-A*0201-restricted CTL epitopes encoded by the tumor-specific MAGE-2 gene product

scientific article published on 01 September 1997

Identification of peptide sequences that potentially trigger HLA‐A2.1‐restricted cytotoxic T lymphocytes ⬇️

scientific article published on June 1, 1993

Identification of peptides for immunotherapy of cancer. It is worth the effort.

scientific article published on January 1, 1998

Immune activation in patients with locally advanced cervical cancer treated with ipilimumab following definitive chemoradiation (GOG-9929)

scientific article published on 18 August 2020

Immunogenicity of an HPV-16 L2 DNA vaccine

scientific article published on 24 June 2009

Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy.

scientific article

Immunological consequences of using three different clinical/laboratory techniques of emulsifying peptide-based vaccines in incomplete Freund's adjuvant

scientific article

Immunological treatment options for locoregionally advanced head and neck squamous cell carcinoma

scientific article

Immunostimulatory Activity of the Cytokine-Based Biologic, IRX-2, on Human Papillomavirus-Exposed Langerhans Cells.

scientific article

Immunotherapy of cancer by peptide-based vaccines for the induction of tumor-specific T cell immunity ⬇️

scientific article published on November 1, 1996

In this issue: targeting Human Papilloma Virus-associated disease, from cervical to head and neck carcinoma…and more.

scientific article published in February 2012

In vivo detection of fluorescent tumor-specific cytotoxic T cell clones

scientific article published on 01 July 1993

In vivo effects of vaccination with six-transmembrane epithelial antigen of the prostate: a candidate antigen for treating prostate cancer.

scientific article

Induction and characterization of cytotoxic T-lymphocytes recognizing a mutated p21ras peptide presented by HLA-A*0201.

scientific article published on May 1995

Induction of HPV16 capsid protein-specific human T cell responses by virus-like particles

scientific article published on March 1999

Inhibition of Langerhans cell maturation by human papillomavirus type 16: a novel role for the annexin A2 heterotetramer in immune suppression

scientific article

Ins and outs of clinical trials with peptide-based vaccines

scientific article

Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cells

scientific article

Investigation of the Optimal Prime Boost Spacing Regimen for a Cancer Therapeutic Vaccine Targeting Human Papillomavirus

scientific article published in 2022

Is sperm protein 17 a useful target for tumor immunotherapy?

scientific article published on 01 September 2003

Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4.

scientific article

L1-specific protection from tumor challenge elicited by HPV16 virus-like particles

scientific article published in October 1998

Langerhans cells and dendritic cells are cytotoxic towards HPV16 E6 and E7 expressing target cells.

scientific article published on 15 November 2007

Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized Poly-I:C

scientific article

Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo

scientific article published on 11 September 2003

Lymph node-targeted immunotherapy mediates potent immunity resulting in regression of isolated or metastatic human papillomavirus-transformed tumors.

scientific article published on 29 September 2009

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences

scientific article published on February 1995

Mechanisms of induction of primary virus-specific cytotoxic T lymphocyte responses

scientific article published on November 1, 1992

Mechanisms used by human papillomaviruses to escape the host immune response.

scientific article published on February 2007

Molecular analysis of human papillomavirus virus-like particle activated Langerhans cells in vitro

scientific article

Molecular characterization of melanoma-derived antigens

scientific article published on 01 January 2001

Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate

scientific article (publication date: August 2001)

Nano-Pulse Stimulation induces immunogenic cell death in human papillomavirus-transformed tumors and initiates an adaptive immune response

scientific article published on 11 January 2018

Nanobody-Antigen Conjugates Elicit HPV-Specific Antitumor Immune Responses

scientific article published on 23 May 2018

Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.

scientific article

Notch-ing from T-cell to B-cell lymphoid malignancies.

scientific article published on September 2011

Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia

scientific article published on 09 December 2011

Past, present, and future of HPV research: highlights from the 19th International Papillomavirus Conference-HPV2001.

scientific article

Peptide selection by MHC class I molecules ⬇️

scientific article published on April 25, 1991

Peptide specificity of alloreactive CD4 positive T lymphocytes directed against a major histocompatibility complex class I disparity

scientific article published on 01 November 1996

Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction.

scientific article published on July 1996

Peptide vaccination with an anchor-replaced CTL epitope protects against human papillomavirus type 16-induced tumors expressing the wild-type epitope

scientific article published on November 1998

Peptide-based cancer vaccines

scientific article published on 01 October 1996

Peptide-based vaccines for cancer immunotherapy

scientific article published on February 2004

Peptide-based vaccines for cancer: realizing their potential

scientific article published on December 2008

Perspective for prophylaxis and treatment of cervical cancer: an immunological approach.

scientific article

Pharmacokinetic differences between a T cell-tolerizing and a T cell-activating peptide

scientific article published on 01 June 2001

Phase 2 trial of combination thalidomide plus temozolomide in patients with metastatic malignant melanoma: Southwest Oncology Group S0508.

scientific article

Prevention is better than cure: the case for clinical trials of therapeutic cancer vaccines in the prophylactic setting

scientific article

Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs.

scientific article published in October 2007

Progress in the development of immunotherapy of cancer using ex vivo-generated dendritic cells expressing multiple tumor antigen epitopes.

scientific article published in January 2004

Prostate cancer immunotherapy yields superior long-term survival in TRAMP mice when administered at an early stage of carcinogenesis prior to the establishment of tumor-associated immunosuppression at later stages

scientific article

Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity

scientific article published on 01 February 2008

Prostate stem cell antigen: a prospective therapeutic and diagnostic target

scientific article published on 05 October 2008

Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide ⬇️

scientific article published on March 15, 1991

Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cells

scientific article published on 05 October 2008

Quantitative MRI cell tracking of immune cell recruitment to tumors and draining lymph nodes in response to anti-PD-1 and a DPX-based immunotherapy

scientific article published on 29 November 2020

Recent advances in strategies for immunotherapy of human papillomavirus-induced lesions.

scientific article published on January 2008

Recent progress in tumour vaccine development

scientific article

Rejection of large HPV-16 expressing tumors in aged mice by a single immunization of VacciMax encapsulated CTL/T helper peptides.

scientific article published on 7 June 2007

Relationship between CD8-dependent antigen recognition, T cell functional avidity, and tumor cell recognition

scientific article published on 03 October 2008

Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI)

scientific article

Reversal of human papillomavirus-specific T cell immune suppression through TLR agonist treatment of Langerhans cells exposed to human papillomavirus type 16.

scientific article published on March 2009

Secretory Leukocyte Protease Inhibitor Expression and High-Risk HPV Infection in Anal Lesions of HIV-Positive Patients.

scientific article published on 4 May 2016

Serum cytokine profiling as a diagnostic and prognostic tool in ovarian cancer: a potential role for interleukin 7

scientific article published on 01 April 2007

Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor.

scientific article published on February 2005

Small molecule inhibitors of the annexin A2 heterotetramer prevent human papillomavirus type 16 infection

scientific article published on 23 February 2015

Sperm fibrous sheath proteins: a potential new class of target antigens for use in human therapeutic cancer vaccines.

scientific article

Sperm protein 17 expression defines 2 subsets of primary esthesioneuroblastoma.

scientific article published in December 2005

Sperm protein 17 is a suitable target for adoptive T-cell-based immunotherapy in human ovarian cancer

scientific article published on October 2008

Sperm protein 17 is expressed in human somatic ciliated epithelia.

scientific article published in April 2004

Sperm protein 17 is expressed in the sperm fibrous sheath

scientific article

Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors

scientific article

Suppression of Langerhans cell activation is conserved amongst human papillomavirus α and β genotypes, but not a µ genotype

scientific article

Syndemic synergy of HPV and other sexually transmitted pathogens in the development of high-grade anal squamous intraepithelial lesions.

scientific article published on 7 November 2017

Synopsis of the 4th Walker's Cay Meeting on Cancer Vaccines, 7-10 March 2002

scientific article published on 26 October 2002

Synopsis of the 5th annual Cancer Vaccines and Immunotherapy Colloquium at Walker's Cay.

scientific article published on 26 August 2003

Synopsis of the 6th Walker's Cay Colloquium on Cancer Vaccines and Immunotherapy

scientific article

T cell ignorance is bliss: T cells are not tolerized by Langerhans cells presenting human papillomavirus antigens in the absence of costimulation

scientific article published on December 2016

T cell infiltration of the prostate induced by androgen withdrawal in patients with prostate cancer

scientific article

T-cell immunotherapy of cancer

scientific article published on June 1991

T-cell receptor tetramer binding or the lack there of does not necessitate antigen reactivity in T-cell receptor transduced T cells.

scientific article published on 23 December 2005

TNFSF14: LIGHTing the Way for Effective Cancer Immunotherapy

scientific article published on 15 May 2020

The Cytoskeletal Adaptor Obscurin-Like 1 Interacts with the Human Papillomavirus 16 (HPV16) Capsid Protein L2 and Is Required for HPV16 Endocytosis.

scientific article published on 21 September 2016

The Essential Role of anxA2 in Langerhans Cell Birbeck Granules Formation

scientific article published on 15 April 2020

The MHC expression of dendritic cells from mouse spleen isolated by centrifugal elutriation is upregulated during short term culture

article

The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells

scientific article published on 01 October 2002

The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection

scientific article published on 22 August 2012

The biological activities of simian virus 40 large-T antigen and its possible oncogenic effects in humans

scientific article published on April 1, 1998

The cell-mediated immune response to human papillomavirus-induced cervical cancer: implications for immunotherapy.

scientific article

The current status of therapeutic HPV vaccine

scientific article

The detection of simian virus 40 in human tumors by polymerase chain reaction.

scientific article published in April 1998

The efficacy of a DNA vaccine containing inserted and replicated regions of the E7 gene for treatment of HPV-16 induced tumors.

scientific article published on 10 January 2007

The evolving field of human papillomavirus receptor research: a review of binding and entry.

scientific article published on 27 March 2013

The level of secretory leukocyte protease inhibitor is decreased in metastatic head and neck squamous cell carcinoma

scientific article

The peroxidation of thiocyanate catalysed by myeloperoxidase and lactoperoxidase

scientific article

Therapeutic efficacy of a human papillomavirus type 16 E7 bacterial exotoxin fusion protein adjuvanted with CpG or GPI-0100 in a preclinical mouse model for HPV-associated disease

scientific article published on 19 April 2019

Therapeutic vaccination for HPV induced cervical cancers

scientific article published on January 2007

Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax

scientific article published on 23 April 2007

Theta-Defensins Inhibit High-Risk Human Papillomavirus Infection Through Charge-Driven Capsid Clustering

scientific article published on 25 September 2020

Thymus dictates major histocompatibility complex (MHC) specificity and immune response gene phenotype of class II MHC-restricted T cells but not of class I MHC-restricted T cells ⬇️

scientific article published on December 1, 1984

Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.

scientific article

T‐Cell Immunotherapy of Tumors by Adoptive Transfer of Cytotoxic T Lymphocytes and by Vaccination with Minimal Essential Epitopes ⬇️

scientific article published on June 1, 1995

Understanding the cross-talk between ovarian tumors and immune cells: mechanisms for effective immunotherapies.

scientific article published on April 2011

Uptake of human papillomavirus virus-like particles by dendritic cells is mediated by Fcgamma receptors and contributes to acquisition of T cell immunity

scientific article

Vaccination against non-mutated neoantigens induced in recurrent and future tumors

scientific article published on 15 April 2020

Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a phase I-II trial

scientific article published on 01 June 1999

Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study

scientific article published on 11 October 2018

rAAV/Her-2/neu loading of dendritic cells for a potent cellular-mediated MHC class I restricted immune response against ovarian cancer.

scientific article

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